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- W3120543732 abstract "We thank Gioia and associates for their interest in our article and the American Journal of Ophthalmology for the opportunity to further clarify our findings. First, it is possible that visual acuity (VA) measurements may be less reliable in individuals with Alzheimer disease (AD), because patients may have limited executive capacity to follow commands. There has been limited research regarding the optimal process for the measurement of VA in individuals with cognitive impairment; however, alternative methods may prove useful. 1 Froiman P.C. Dantas P.E.C. Assessment of visual acuity in patients with dementia using teller acuity cards. Strabismus. 2013; 21: 93-97 Crossref PubMed Scopus (12) Google Scholar Given the need for standardized measurements of VA across all groups, we elected to use Snellen distance corrected VA measurement. Eyes with worse than 20/40 vision were excluded from our study; despite this, individuals with AD had worse VA on average than those with mild cognitive impairment or healthy control subjects. This could be due, in part, as Gioia and associates suggest, to the challenge of measuring VA in individuals with AD. It is also important to recognize that individuals with cognitive impairment and their families may choose to defer or delay cataract surgery or may have visual impairment associated with underlying AD pathophysiology. 2 Marquié M. Castilla-Martí M. Valero S. et al. Visual impairment in aging and cognitive decline: Experience in a Memory Clinic. Sci Rep. 2019; 9: 8698 Crossref PubMed Scopus (13) Google Scholar Given these concerns, we controlled for VA as a covariate in our multivariable analysis in order to minimize confounding. Comment on: Choroidal Structural Analysis in Alzheimer Disease, Mild Cognitive Impairment, and Cognitively Healthy ControlsAmerican Journal of OphthalmologyVol. 225PreviewWe read with great interest the article by Robbins and associates1 titled “Choroidal structural analysis in Alzheimer disease, mild cognitive impairment, and cognitively healthy controls.” Full-Text PDF" @default.
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- W3120543732 date "2021-05-01" @default.
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- W3120543732 title "Reply to: “Comment on Choroidal Structural Analysis in Alzheimer Disease, Mild Cognitive Impairment, and Cognitively Healthy Controls”" @default.
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- W3120543732 doi "https://doi.org/10.1016/j.ajo.2021.01.003" @default.
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