FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120643555> ?p ?o ?g. }

• W3120643555 abstract "Abstract Background Guidelines do not recommend surgery for patients with oligometastatic disease from esophagogastric adenocarcinoma (EGAC), although some studies suggest a more favorable survival. We analyzed the outcome of oligometastatic EGAC receiving FLOT chemotherapy followed by surgery. Methods The data of patients with either pre-therapeutic, post-neoadjuvant or intraoperative clinical diagnosis of oligometastatic EGAC were extracted from a prospective database of the 2009–2018 treatment period. 48 consecutive patients were identified with oligometastatic disease, who underwent perioperative chemotherapy plus surgery. We retrospectively analyzed surgical outcome and overall survival. Results The overall 5-year survival was 18%. 12 patients (25%) with pre-therapeutic oligometastatic EGAC, who had no histologic vital tumor evidence of metastases after surgery had a survival rate of 48% compared to an 11% 5-year survival rate of 36 patients (75%), who had histologic vital tumor metastatic evidence after FLOT chemotherapy and surgical resection (p = 0.012). The survival rates after R0, R1 and R2 (non-resected metastases) resection were 21% (n = 33), 0% (n = 4) and 17% (n = 11), respectively (p = 0.273). Conclusion Oligometastatic EGAC is associated with poor overall survival even after complete resection of all tumor manifestations. The subgroup of patients with a complete histologic response of metastatic lesions to neoadjuvant FLOT shows 5-year survival rates similar to non-metastatic EGAC. Trial registration Not applicable." @default.
• W3120643555 created "2021-01-18" @default.
• W3120643555 creator A5013287548 @default.
• W3120643555 creator A5017432068 @default.
• W3120643555 creator A5032586823 @default.
• W3120643555 creator A5035153025 @default.
• W3120643555 creator A5037965175 @default.
• W3120643555 creator A5080709924 @default.
• W3120643555 date "2021-01-13" @default.
• W3120643555 modified "2023-09-27" @default.
• W3120643555 title "Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival" @default.
• W3120643555 cites W1857963415 @default.
• W3120643555 cites W1977079175 @default.
• W3120643555 cites W2007900522 @default.
• W3120643555 cites W2037132328 @default.
• W3120643555 cites W2064289791 @default.
• W3120643555 cites W2070555748 @default.
• W3120643555 cites W2096998881 @default.
• W3120643555 cites W2101815035 @default.
• W3120643555 cites W2107382352 @default.
• W3120643555 cites W2113236094 @default.
• W3120643555 cites W2115072149 @default.
• W3120643555 cites W2128998354 @default.
• W3120643555 cites W2157769714 @default.
• W3120643555 cites W2251541509 @default.
• W3120643555 cites W2318163227 @default.
• W3120643555 cites W2563453438 @default.
• W3120643555 cites W2587773288 @default.
• W3120643555 cites W2597821533 @default.
• W3120643555 cites W2609897303 @default.
• W3120643555 cites W2777030709 @default.
• W3120643555 cites W2791356926 @default.
• W3120643555 cites W2794787607 @default.
• W3120643555 cites W2803498509 @default.
• W3120643555 cites W2937968791 @default.
• W3120643555 cites W2938774982 @default.
• W3120643555 cites W2942843443 @default.
• W3120643555 cites W2942860188 @default.
• W3120643555 cites W2944758447 @default.
• W3120643555 cites W2946783258 @default.
• W3120643555 cites W2949206562 @default.
• W3120643555 cites W2951091238 @default.
• W3120643555 doi "https://doi.org/10.1186/s12893-020-01035-9" @default.
• W3120643555 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7805136" @default.
• W3120643555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33435947" @default.
• W3120643555 hasPublicationYear "2021" @default.
• W3120643555 type Work @default.
• W3120643555 sameAs 3120643555 @default.
• W3120643555 citedByCount "2" @default.
• W3120643555 countsByYear W31206435552023 @default.
• W3120643555 crossrefType "journal-article" @default.
• W3120643555 hasAuthorship W3120643555A5013287548 @default.
• W3120643555 hasAuthorship W3120643555A5017432068 @default.
• W3120643555 hasAuthorship W3120643555A5032586823 @default.
• W3120643555 hasAuthorship W3120643555A5035153025 @default.
• W3120643555 hasAuthorship W3120643555A5037965175 @default.
• W3120643555 hasAuthorship W3120643555A5080709924 @default.
• W3120643555 hasBestOaLocation W31206435551 @default.
• W3120643555 hasConcept C121608353 @default.
• W3120643555 hasConcept C126322002 @default.
• W3120643555 hasConcept C141071460 @default.
• W3120643555 hasConcept C143998085 @default.
• W3120643555 hasConcept C2776283816 @default.
• W3120643555 hasConcept C2776694085 @default.
• W3120643555 hasConcept C2778292576 @default.
• W3120643555 hasConcept C2781182431 @default.
• W3120643555 hasConcept C31174226 @default.
• W3120643555 hasConcept C530470458 @default.
• W3120643555 hasConcept C71924100 @default.
• W3120643555 hasConceptScore W3120643555C121608353 @default.
• W3120643555 hasConceptScore W3120643555C126322002 @default.
• W3120643555 hasConceptScore W3120643555C141071460 @default.
• W3120643555 hasConceptScore W3120643555C143998085 @default.
• W3120643555 hasConceptScore W3120643555C2776283816 @default.
• W3120643555 hasConceptScore W3120643555C2776694085 @default.
• W3120643555 hasConceptScore W3120643555C2778292576 @default.
• W3120643555 hasConceptScore W3120643555C2781182431 @default.
• W3120643555 hasConceptScore W3120643555C31174226 @default.
• W3120643555 hasConceptScore W3120643555C530470458 @default.
• W3120643555 hasConceptScore W3120643555C71924100 @default.
• W3120643555 hasIssue "1" @default.
• W3120643555 hasLocation W31206435551 @default.
• W3120643555 hasLocation W31206435552 @default.
• W3120643555 hasLocation W31206435553 @default.
• W3120643555 hasOpenAccess W3120643555 @default.
• W3120643555 hasPrimaryLocation W31206435551 @default.
• W3120643555 hasRelatedWork W1255356622 @default.
• W3120643555 hasRelatedWork W2105895425 @default.
• W3120643555 hasRelatedWork W2358701816 @default.
• W3120643555 hasRelatedWork W2367105124 @default.
• W3120643555 hasRelatedWork W2368979736 @default.
• W3120643555 hasRelatedWork W2390548009 @default.
• W3120643555 hasRelatedWork W2404042595 @default.
• W3120643555 hasRelatedWork W3089077900 @default.
• W3120643555 hasRelatedWork W3092055942 @default.
• W3120643555 hasRelatedWork W3205916391 @default.
• W3120643555 hasVolume "21" @default.
• W3120643555 isParatext "false" @default.
• W3120643555 isRetracted "false" @default.
• W3120643555 magId "3120643555" @default.

• next