Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120768635> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3120768635 abstract "Background: Carotid atherosclerotic disease is associated with aortic stenosis and reduced cardiac function. The causality between carotid and cardiac pathologies is unknown. We aim to explore the effects of carotid stenosis or occlusion on cardiac pathology and function. Methods and Results: We produced carotid obstruction or stenosis in 36 atherogenic mice with 150- or 300-μm tandem surgery or sham surgery. The structure and function of the heart were assessed by histology and animal ultrasound. The 150-μm group had larger plaque burden and thicker valve leaflets in the aortic root than did the control group. Also, the two surgery groups had a thicker left ventricular posterior wall and smaller internal diameter compared with controls. Increased myocardial fibrosis was also found in the 150-μm group compared with controls, although the surgery groups had preserved systolic function compared with that of controls. Conclusions: In a mouse model, carotid occlusion accentuated the formation of aortic stenosis and promoted ventricular remodeling without impairing systolic function. Carotid atherosclerotic plaque may be a pathogenic factor for aortic stenosis and ventricular remodeling." @default.
- W3120768635 created "2021-01-18" @default.
- W3120768635 creator A5014061343 @default.
- W3120768635 creator A5022201710 @default.
- W3120768635 creator A5054042816 @default.
- W3120768635 date "2021-01-11" @default.
- W3120768635 modified "2023-10-12" @default.
- W3120768635 title "Carotid Occlusion Accentuates Aortic Stenosis and Cardiac Remodeling With Preserved Systolic Function in LDL Receptor-Deficient Mice" @default.
- W3120768635 cites W1125121739 @default.
- W3120768635 cites W1488531495 @default.
- W3120768635 cites W1866765074 @default.
- W3120768635 cites W2081201714 @default.
- W3120768635 cites W2100194095 @default.
- W3120768635 cites W2111876763 @default.
- W3120768635 cites W2124232762 @default.
- W3120768635 cites W2147390389 @default.
- W3120768635 cites W2151247869 @default.
- W3120768635 cites W2154073422 @default.
- W3120768635 cites W2297469630 @default.
- W3120768635 cites W2804403488 @default.
- W3120768635 cites W3018519772 @default.
- W3120768635 cites W3070114542 @default.
- W3120768635 doi "https://doi.org/10.3389/fphys.2020.578722" @default.
- W3120768635 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7873957" @default.
- W3120768635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33584325" @default.
- W3120768635 hasPublicationYear "2021" @default.
- W3120768635 type Work @default.
- W3120768635 sameAs 3120768635 @default.
- W3120768635 citedByCount "1" @default.
- W3120768635 countsByYear W31207686352023 @default.
- W3120768635 crossrefType "journal-article" @default.
- W3120768635 hasAuthorship W3120768635A5014061343 @default.
- W3120768635 hasAuthorship W3120768635A5022201710 @default.
- W3120768635 hasAuthorship W3120768635A5054042816 @default.
- W3120768635 hasBestOaLocation W31207686351 @default.
- W3120768635 hasConcept C111566952 @default.
- W3120768635 hasConcept C126322002 @default.
- W3120768635 hasConcept C164705383 @default.
- W3120768635 hasConcept C2776268601 @default.
- W3120768635 hasConcept C2778198053 @default.
- W3120768635 hasConcept C2780007028 @default.
- W3120768635 hasConcept C2780559512 @default.
- W3120768635 hasConcept C2781414266 @default.
- W3120768635 hasConcept C71924100 @default.
- W3120768635 hasConceptScore W3120768635C111566952 @default.
- W3120768635 hasConceptScore W3120768635C126322002 @default.
- W3120768635 hasConceptScore W3120768635C164705383 @default.
- W3120768635 hasConceptScore W3120768635C2776268601 @default.
- W3120768635 hasConceptScore W3120768635C2778198053 @default.
- W3120768635 hasConceptScore W3120768635C2780007028 @default.
- W3120768635 hasConceptScore W3120768635C2780559512 @default.
- W3120768635 hasConceptScore W3120768635C2781414266 @default.
- W3120768635 hasConceptScore W3120768635C71924100 @default.
- W3120768635 hasFunder F4320321001 @default.
- W3120768635 hasLocation W31207686351 @default.
- W3120768635 hasLocation W31207686352 @default.
- W3120768635 hasLocation W31207686353 @default.
- W3120768635 hasOpenAccess W3120768635 @default.
- W3120768635 hasPrimaryLocation W31207686351 @default.
- W3120768635 hasRelatedWork W12761856 @default.
- W3120768635 hasRelatedWork W14202666 @default.
- W3120768635 hasRelatedWork W1476038 @default.
- W3120768635 hasRelatedWork W16534786 @default.
- W3120768635 hasRelatedWork W17011612 @default.
- W3120768635 hasRelatedWork W3337612 @default.
- W3120768635 hasRelatedWork W3483587 @default.
- W3120768635 hasRelatedWork W9156717 @default.
- W3120768635 hasRelatedWork W9688522 @default.
- W3120768635 hasRelatedWork W11817617 @default.
- W3120768635 hasVolume "11" @default.
- W3120768635 isParatext "false" @default.
- W3120768635 isRetracted "false" @default.
- W3120768635 magId "3120768635" @default.
- W3120768635 workType "article" @default.