FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120819982> ?p ?o ?g. }

• W3120819982 endingPage "116480" @default.
• W3120819982 startingPage "116480" @default.
• W3120819982 abstract "Four most concerned heavy metal pollutants, arsenic, cadmium, lead, and mercury may share common mechanisms to induce metabolic syndrome (MetS). However, recent studies exploring the relationships between MetS and metal exposure presented inconsistent findings. We aimed to clarify the relationship between heavy metal exposure biomarkers and MetS using a meta-analysis and systematic review approach. Literature search was conducted in international and the Chinese national databases up to June 2020. Of selected studies, we extracted the relevant data and evaluated the quality of each study’s methodology. We then calculated the pooled effect sizes (ESs), standardized mean differences (SMDs), and their 95% confidence intervals (CIs) using a random-effect meta-analysis approach followed by stratification analyses for control of potential confounders. Involving 55,536 participants, the included 22 articles covered 52 observational studies reporting ESs and/or metal concentrations on specific metal and gender. Our results show that participants with MetS had significantly higher levels of heavy metal exposure [pooled ES = 1.16, 95% CI: 1.09, 1.23; n = 42, heterogeneity I 2 = 75.6%; and SMD = 0.22, 95% CI: 0.15, 0.29; n = 32, I 2 = 94.2%] than those without MetS. Pooled ESs in the subgroups stratified by arsenic, cadmium, lead, and mercury were 1.04 (95% CI: 0.97, 1.10; n = 8, I 2 = 61.0%), 1.10 (0.95, 1.27; 11, 45.0%), 1.21 (1.00, 1.48; 12, 82.9%), and 1.26 (1.06, 1.48; 11, 67.7%), respectively. Pooled ESs in the subgroups stratified by blood, urine, and the other specimen were 1.22 (95% CI: 1.08, 1.38; n = 26, I 2 = 75.8%), 1.06 (1.00, 1.13; 14, 58.1%), and 2.41 (1.30, 4.43; 2, 0.0%), respectively. In conclusion, heavy metal exposure was positively associated with MetS. Further studies are warranted to examine the effects of individual metals and their interaction on the relationship between MetS and heavy metals. • Metabolic syndrome (MetS) is threatening human health globally at a high prevalence. • Heavy metals (arsenic, cadmium, lead, and mercury) share mechanisms inducing MetS. • Heavy metal exposure to MetS risk was meta-analyzed by including 55,536 subjects. • Studies meeting the inclusion criteria for meta-analysis were of observational design. • Lead and mercury but not arsenic and cadmium were prominently correlated with MetS. The exposure to heavy metals was positively associated with the prevalence of metabolic syndrome. Exposures to lead and mercury had a stronger association with the risk of metabolic syndrome." @default.
• W3120819982 created "2021-01-18" @default.
• W3120819982 creator A5011416614 @default.
• W3120819982 creator A5014116362 @default.
• W3120819982 creator A5052399364 @default.
• W3120819982 creator A5075801002 @default.
• W3120819982 creator A5077155065 @default.
• W3120819982 creator A5084874107 @default.
• W3120819982 date "2021-03-01" @default.
• W3120819982 modified "2023-10-16" @default.
• W3120819982 title "Associations between metabolic syndrome and four heavy metals: A systematic review and meta-analysis" @default.
• W3120819982 cites W1057688359 @default.
• W3120819982 cites W1574029579 @default.
• W3120819982 cites W1579491283 @default.
• W3120819982 cites W1830275345 @default.
• W3120819982 cites W1837193075 @default.
• W3120819982 cites W1880250511 @default.
• W3120819982 cites W1963739832 @default.
• W3120819982 cites W1966521314 @default.
• W3120819982 cites W1973842058 @default.
• W3120819982 cites W1976161197 @default.
• W3120819982 cites W1979423827 @default.
• W3120819982 cites W1980167516 @default.
• W3120819982 cites W1987319584 @default.
• W3120819982 cites W1992404935 @default.
• W3120819982 cites W1995478356 @default.
• W3120819982 cites W1996270665 @default.
• W3120819982 cites W1997843365 @default.
• W3120819982 cites W1998697859 @default.
• W3120819982 cites W2001184683 @default.
• W3120819982 cites W2007431652 @default.
• W3120819982 cites W2008841390 @default.
• W3120819982 cites W2013158398 @default.
• W3120819982 cites W2013816446 @default.
• W3120819982 cites W2013862634 @default.
• W3120819982 cites W2027823140 @default.
• W3120819982 cites W2028514363 @default.
• W3120819982 cites W2036664270 @default.
• W3120819982 cites W2041182355 @default.
• W3120819982 cites W2042063368 @default.
• W3120819982 cites W2045204738 @default.
• W3120819982 cites W2049638137 @default.
• W3120819982 cites W2061459507 @default.
• W3120819982 cites W2065258985 @default.
• W3120819982 cites W2071470452 @default.
• W3120819982 cites W2081486807 @default.
• W3120819982 cites W2081851012 @default.
• W3120819982 cites W2087144845 @default.
• W3120819982 cites W2087999767 @default.
• W3120819982 cites W2091154592 @default.
• W3120819982 cites W2100229266 @default.
• W3120819982 cites W2116475791 @default.
• W3120819982 cites W2122139131 @default.
• W3120819982 cites W2123142754 @default.
• W3120819982 cites W2125435699 @default.
• W3120819982 cites W2128099976 @default.
• W3120819982 cites W2131052423 @default.
• W3120819982 cites W2139424930 @default.
• W3120819982 cites W2143104968 @default.
• W3120819982 cites W2151701113 @default.
• W3120819982 cites W2158411703 @default.
• W3120819982 cites W2159727241 @default.
• W3120819982 cites W2161552991 @default.
• W3120819982 cites W2165771849 @default.
• W3120819982 cites W2165999869 @default.
• W3120819982 cites W2192900559 @default.
• W3120819982 cites W2195785268 @default.
• W3120819982 cites W2201045159 @default.
• W3120819982 cites W2233531330 @default.
• W3120819982 cites W2329222943 @default.
• W3120819982 cites W2341072750 @default.
• W3120819982 cites W2389444749 @default.
• W3120819982 cites W2413919881 @default.
• W3120819982 cites W2419587660 @default.
• W3120819982 cites W2436046942 @default.
• W3120819982 cites W2463086325 @default.
• W3120819982 cites W2475056155 @default.
• W3120819982 cites W2492282451 @default.
• W3120819982 cites W2509476325 @default.
• W3120819982 cites W2513245087 @default.
• W3120819982 cites W2522031181 @default.
• W3120819982 cites W2533693668 @default.
• W3120819982 cites W2535762306 @default.
• W3120819982 cites W2564017101 @default.
• W3120819982 cites W2564896212 @default.
• W3120819982 cites W2564935797 @default.
• W3120819982 cites W2571450722 @default.
• W3120819982 cites W2589631934 @default.
• W3120819982 cites W2599844136 @default.
• W3120819982 cites W2610582730 @default.
• W3120819982 cites W2743751242 @default.
• W3120819982 cites W2763629860 @default.
• W3120819982 cites W2765524414 @default.
• W3120819982 cites W2765818725 @default.
• W3120819982 cites W2769451956 @default.
• W3120819982 cites W2772546906 @default.
• W3120819982 cites W2781782292 @default.
• W3120819982 cites W2789424402 @default.

• next