FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120852651> ?p ?o ?g. }

• W3120852651 endingPage "571" @default.
• W3120852651 startingPage "562" @default.
• W3120852651 abstract "Sarcoidosis is a systemic granulomatous disease that in most patients affects the lung. Pulmonary fibrotic sarcoidosis is clinically, radiologically, and pathologically a heterogeneous condition. Although substantial indirect evidence suggests small airways involvement, direct evidence currently is lacking.What is the role of the (small) airways in fibrotic sarcoidosis?Airway morphologic features were investigated in seven explant lungs with end-stage fibrotic sarcoidosis using a combination of CT scanning (large airways), micro-CT scanning (small airways), and histologic examination and compared with seven unused donor lungs as controls with specific attention focused on different radiologically defined sarcoidosis subtypes.Patients with central bronchial distortion (n = 3), diffuse bronchiectasis (n = 3), and usual interstitial pneumonia pattern (n = 1) were identified based on CT scan, showing a decrease and narrowing of large airways, a similar airway number and increased airway diameter of more distal airways, or an increase in airway number and airway diameter, respectively, compared with control participants. The number of terminal bronchioles per milliliter and the total number of terminal bronchioles were decreased in all forms of fibrotic sarcoidosis. Interestingly, the number of terminal bronchioles was inversely correlated with the degree of fibrosis. Furthermore, we identified granulomatous remodeling as a cause of small airways loss using serial micro-CT scanning and histologic examination.The large airways are involved differentially in subtypes of sarcoidosis, but the terminal bronchioles universally are lost. This suggests that small airways loss forms an important aspect in the pathophysiologic features of fibrotic pulmonary sarcoidosis." @default.
• W3120852651 created "2021-01-18" @default.
• W3120852651 creator A5002276916 @default.
• W3120852651 creator A5005955868 @default.
• W3120852651 creator A5009982067 @default.
• W3120852651 creator A5033618310 @default.
• W3120852651 creator A5034996987 @default.
• W3120852651 creator A5036906731 @default.
• W3120852651 creator A5038120191 @default.
• W3120852651 creator A5038207515 @default.
• W3120852651 creator A5052357595 @default.
• W3120852651 creator A5055245374 @default.
• W3120852651 creator A5057394108 @default.
• W3120852651 creator A5069455180 @default.
• W3120852651 creator A5071970006 @default.
• W3120852651 creator A5072866280 @default.
• W3120852651 creator A5079519206 @default.
• W3120852651 creator A5086331193 @default.
• W3120852651 date "2021-08-01" @default.
• W3120852651 modified "2023-10-14" @default.
• W3120852651 title "Distinct Airway Involvement in Subtypes of End-Stage Fibrotic Pulmonary Sarcoidosis" @default.
• W3120852651 cites W1986614167 @default.
• W3120852651 cites W1997073223 @default.
• W3120852651 cites W2001227409 @default.
• W3120852651 cites W2003493421 @default.
• W3120852651 cites W2015963867 @default.
• W3120852651 cites W2042144005 @default.
• W3120852651 cites W2062231972 @default.
• W3120852651 cites W2074372507 @default.
• W3120852651 cites W2088229788 @default.
• W3120852651 cites W2089418479 @default.
• W3120852651 cites W2094338449 @default.
• W3120852651 cites W2102634410 @default.
• W3120852651 cites W2127890285 @default.
• W3120852651 cites W2150899860 @default.
• W3120852651 cites W2163825747 @default.
• W3120852651 cites W2170412345 @default.
• W3120852651 cites W2469573556 @default.
• W3120852651 cites W2967129829 @default.
• W3120852651 cites W3005995130 @default.
• W3120852651 cites W3007861568 @default.
• W3120852651 cites W4211032738 @default.
• W3120852651 cites W772708467 @default.
• W3120852651 doi "https://doi.org/10.1016/j.chest.2021.01.003" @default.
• W3120852651 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33440183" @default.
• W3120852651 hasPublicationYear "2021" @default.
• W3120852651 type Work @default.
• W3120852651 sameAs 3120852651 @default.
• W3120852651 citedByCount "8" @default.
• W3120852651 countsByYear W31208526512021 @default.
• W3120852651 countsByYear W31208526512022 @default.
• W3120852651 countsByYear W31208526512023 @default.
• W3120852651 crossrefType "journal-article" @default.
• W3120852651 hasAuthorship W3120852651A5002276916 @default.
• W3120852651 hasAuthorship W3120852651A5005955868 @default.
• W3120852651 hasAuthorship W3120852651A5009982067 @default.
• W3120852651 hasAuthorship W3120852651A5033618310 @default.
• W3120852651 hasAuthorship W3120852651A5034996987 @default.
• W3120852651 hasAuthorship W3120852651A5036906731 @default.
• W3120852651 hasAuthorship W3120852651A5038120191 @default.
• W3120852651 hasAuthorship W3120852651A5038207515 @default.
• W3120852651 hasAuthorship W3120852651A5052357595 @default.
• W3120852651 hasAuthorship W3120852651A5055245374 @default.
• W3120852651 hasAuthorship W3120852651A5057394108 @default.
• W3120852651 hasAuthorship W3120852651A5069455180 @default.
• W3120852651 hasAuthorship W3120852651A5071970006 @default.
• W3120852651 hasAuthorship W3120852651A5072866280 @default.
• W3120852651 hasAuthorship W3120852651A5079519206 @default.
• W3120852651 hasAuthorship W3120852651A5086331193 @default.
• W3120852651 hasBestOaLocation W31208526511 @default.
• W3120852651 hasConcept C105922876 @default.
• W3120852651 hasConcept C126322002 @default.
• W3120852651 hasConcept C141071460 @default.
• W3120852651 hasConcept C142724271 @default.
• W3120852651 hasConcept C2777714996 @default.
• W3120852651 hasConcept C2778341716 @default.
• W3120852651 hasConcept C2779379686 @default.
• W3120852651 hasConcept C2780559512 @default.
• W3120852651 hasConcept C2781301800 @default.
• W3120852651 hasConcept C2909011058 @default.
• W3120852651 hasConcept C71924100 @default.
• W3120852651 hasConceptScore W3120852651C105922876 @default.
• W3120852651 hasConceptScore W3120852651C126322002 @default.
• W3120852651 hasConceptScore W3120852651C141071460 @default.
• W3120852651 hasConceptScore W3120852651C142724271 @default.
• W3120852651 hasConceptScore W3120852651C2777714996 @default.
• W3120852651 hasConceptScore W3120852651C2778341716 @default.
• W3120852651 hasConceptScore W3120852651C2779379686 @default.
• W3120852651 hasConceptScore W3120852651C2780559512 @default.
• W3120852651 hasConceptScore W3120852651C2781301800 @default.
• W3120852651 hasConceptScore W3120852651C2909011058 @default.
• W3120852651 hasConceptScore W3120852651C71924100 @default.
• W3120852651 hasFunder F4320321730 @default.
• W3120852651 hasFunder F4320322308 @default.
• W3120852651 hasIssue "2" @default.
• W3120852651 hasLocation W31208526511 @default.
• W3120852651 hasLocation W31208526512 @default.
• W3120852651 hasLocation W31208526513 @default.

• next