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- W3120908040 endingPage "107701" @default.
- W3120908040 startingPage "107701" @default.
- W3120908040 abstract "Epilepsy is a devastating neurological disorder characterized by the repeated occurrence of epileptic seizures. Epilepsy stands as a global health concern affecting around 70 million people worldwide. The mainstream antiepileptic drugs (AEDs) only exert symptomatic relief and drug-resistant epilepsy occurs in up to 33 percent of patients. Hence, the investigation of novel therapeutic strategies against epileptic seizures that could exert disease modifying effects is of paramount importance. In this context, compounds of natural origin with potential antiepileptic properties have recently gained increasing attention. Quercetin is a plant-derived flavonoid with several pharmacological activities. Emerging evidence has demonstrated the antiepileptic potential of quercetin as well. Herein, based on the available evidence, we discuss the neuroprotective effects of quercetin against epileptic seizures and further analyze the plausible underlying molecular mechanisms. Our review suggests that quercetin might be a potential therapeutic candidate against epilepsy that deserves further investigation, and paves the way for the development of plant-derived antiepileptic treatment approaches." @default.
- W3120908040 created "2021-01-18" @default.
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- W3120908040 creator A5083162439 @default.
- W3120908040 creator A5085643475 @default.
- W3120908040 date "2021-02-01" @default.
- W3120908040 modified "2023-09-27" @default.
- W3120908040 title "Enlightening the neuroprotective effect of quercetin in epilepsy: From mechanism to therapeutic opportunities" @default.
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- W3120908040 doi "https://doi.org/10.1016/j.yebeh.2020.107701" @default.
- W3120908040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33412369" @default.
- W3120908040 hasPublicationYear "2021" @default.
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