Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120947223> ?p ?o ?g. }
- W3120947223 endingPage "e0244320" @default.
- W3120947223 startingPage "e0244320" @default.
- W3120947223 abstract "In some patients, migraine attacks are associated with symptoms of allodynia which can be localized (cephalic) or generalized (extracephalic). Using functional neuroimaging and cutaneous thermal stimulation, we aimed to investigate the differences in brain activation of patients with episodic migraine (n = 19) based on their allodynic status defined by changes between ictal and interictal pain tolerance threshold for each subject at the time of imaging. In this prospective imaging study, differences were found in brain activity between the ictal and interictal visits in the brainstem/pons, thalamus, insula, cerebellum and cingulate cortex. Significant differences were also observed in the pattern of activation along the trigeminal pathway to noxious heat stimuli in no allodynia vs. generalized allodynia in the thalamus and the trigeminal nucleus but there were no activation differences in the trigeminal ganglion. The functional magnetic resonance imaging (fMRI) findings provide direct evidence for the view that in migraine patients who are allodynic during the ictal phase of their attacks, the spinal trigeminal nucleus and posterior thalamus become hyper-responsive (sensitized)–to the extent that they mediate cephalic and extracephalic allodynia, respectively. In addition, descending analgesic systems seem as “switched off” in generalized allodynia." @default.
- W3120947223 created "2021-01-18" @default.
- W3120947223 creator A5016966448 @default.
- W3120947223 creator A5037889351 @default.
- W3120947223 creator A5045272723 @default.
- W3120947223 creator A5062546791 @default.
- W3120947223 creator A5064996702 @default.
- W3120947223 creator A5069846932 @default.
- W3120947223 creator A5091764355 @default.
- W3120947223 date "2021-01-04" @default.
- W3120947223 modified "2023-10-15" @default.
- W3120947223 title "Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia" @default.
- W3120947223 cites W1849480202 @default.
- W3120947223 cites W1966041812 @default.
- W3120947223 cites W1987978162 @default.
- W3120947223 cites W1992462403 @default.
- W3120947223 cites W1995411317 @default.
- W3120947223 cites W1995772795 @default.
- W3120947223 cites W2019927207 @default.
- W3120947223 cites W2028850601 @default.
- W3120947223 cites W2030849930 @default.
- W3120947223 cites W2039046404 @default.
- W3120947223 cites W2040792219 @default.
- W3120947223 cites W2042624620 @default.
- W3120947223 cites W2055769861 @default.
- W3120947223 cites W2057904785 @default.
- W3120947223 cites W2058582924 @default.
- W3120947223 cites W2060223399 @default.
- W3120947223 cites W2061370395 @default.
- W3120947223 cites W2070949043 @default.
- W3120947223 cites W2080646080 @default.
- W3120947223 cites W2082984131 @default.
- W3120947223 cites W2084013618 @default.
- W3120947223 cites W2086327013 @default.
- W3120947223 cites W2094846485 @default.
- W3120947223 cites W2096198144 @default.
- W3120947223 cites W2096980067 @default.
- W3120947223 cites W2103649969 @default.
- W3120947223 cites W2113226190 @default.
- W3120947223 cites W2116136260 @default.
- W3120947223 cites W2124163204 @default.
- W3120947223 cites W2125868297 @default.
- W3120947223 cites W2127347157 @default.
- W3120947223 cites W2142552184 @default.
- W3120947223 cites W2143895814 @default.
- W3120947223 cites W2150027687 @default.
- W3120947223 cites W2157163008 @default.
- W3120947223 cites W2287403089 @default.
- W3120947223 cites W2301669941 @default.
- W3120947223 cites W2337586818 @default.
- W3120947223 cites W2493390132 @default.
- W3120947223 cites W2547137906 @default.
- W3120947223 cites W2663247404 @default.
- W3120947223 cites W2738134472 @default.
- W3120947223 cites W2803889346 @default.
- W3120947223 cites W2885400104 @default.
- W3120947223 cites W2900267857 @default.
- W3120947223 cites W2905279275 @default.
- W3120947223 cites W2912373930 @default.
- W3120947223 cites W2925087378 @default.
- W3120947223 cites W2959767426 @default.
- W3120947223 cites W4251914094 @default.
- W3120947223 cites W46438429 @default.
- W3120947223 doi "https://doi.org/10.1371/journal.pone.0244320" @default.
- W3120947223 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7781392" @default.
- W3120947223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33395413" @default.
- W3120947223 hasPublicationYear "2021" @default.
- W3120947223 type Work @default.
- W3120947223 sameAs 3120947223 @default.
- W3120947223 citedByCount "24" @default.
- W3120947223 countsByYear W31209472232021 @default.
- W3120947223 countsByYear W31209472232022 @default.
- W3120947223 countsByYear W31209472232023 @default.
- W3120947223 crossrefType "journal-article" @default.
- W3120947223 hasAuthorship W3120947223A5016966448 @default.
- W3120947223 hasAuthorship W3120947223A5037889351 @default.
- W3120947223 hasAuthorship W3120947223A5045272723 @default.
- W3120947223 hasAuthorship W3120947223A5062546791 @default.
- W3120947223 hasAuthorship W3120947223A5064996702 @default.
- W3120947223 hasAuthorship W3120947223A5069846932 @default.
- W3120947223 hasAuthorship W3120947223A5091764355 @default.
- W3120947223 hasBestOaLocation W31209472231 @default.
- W3120947223 hasConcept C126322002 @default.
- W3120947223 hasConcept C15490471 @default.
- W3120947223 hasConcept C15744967 @default.
- W3120947223 hasConcept C169760540 @default.
- W3120947223 hasConcept C170493617 @default.
- W3120947223 hasConcept C17755696 @default.
- W3120947223 hasConcept C2776700747 @default.
- W3120947223 hasConcept C2777883359 @default.
- W3120947223 hasConcept C2778186239 @default.
- W3120947223 hasConcept C2778541695 @default.
- W3120947223 hasConcept C2779226451 @default.
- W3120947223 hasConcept C2779245659 @default.
- W3120947223 hasConcept C2779246727 @default.
- W3120947223 hasConcept C42219234 @default.
- W3120947223 hasConcept C551621295 @default.
- W3120947223 hasConcept C71924100 @default.