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- W3121059830 endingPage "611" @default.
- W3121059830 startingPage "594" @default.
- W3121059830 abstract "The onset of scleral necrosis after ocular surgery may have catastrophic ocular and systemic consequences. The two most frequent surgeries causing surgically-induced scleral necrosis (SISN) are pterygium excision and cataract extraction. Several pathogenic mechanisms are involved in surgically induced scleral necrosis. All of them are poorly understood. Ocular trauma increasing lytic action of collagenases with subsequent collagen degradation, vascular disruption leading to local ischemia, and immune complex deposition activating the complement system represents some of the events that lead to scleral necrosis. The complex cascade of events involving different pathogenic mechanisms and the patient's abnormal immune response frequently leads to delayed wound healing that predisposes the development of scleral necrosis. The management of SISN ranges from short-term systemic anti-inflammatory drugs to aggressive immunosuppressive therapy and surgical repair. Therefore, before performing any ocular surgery involving the sclera, a thorough ophthalmic and systemic evaluation must be done to identify high-risk patients that may develop SISN." @default.
- W3121059830 created "2021-01-18" @default.
- W3121059830 creator A5040930560 @default.
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- W3121059830 creator A5061847571 @default.
- W3121059830 creator A5073077641 @default.
- W3121059830 creator A5084174611 @default.
- W3121059830 date "2021-07-01" @default.
- W3121059830 modified "2023-10-16" @default.
- W3121059830 title "The clinical and pathogenic spectrum of surgically-induced scleral necrosis: A review" @default.
- W3121059830 cites W121917239 @default.
- W3121059830 cites W1490991609 @default.
- W3121059830 cites W161078118 @default.
- W3121059830 cites W1849615466 @default.
- W3121059830 cites W1939839245 @default.
- W3121059830 cites W1966305764 @default.
- W3121059830 cites W1966693846 @default.
- W3121059830 cites W1968778318 @default.
- W3121059830 cites W1969531043 @default.
- W3121059830 cites W1973684188 @default.
- W3121059830 cites W1974796018 @default.
- W3121059830 cites W1975168703 @default.
- W3121059830 cites W1975337041 @default.
- W3121059830 cites W1976111395 @default.
- W3121059830 cites W1978064599 @default.
- W3121059830 cites W1979271071 @default.
- W3121059830 cites W1980645903 @default.
- W3121059830 cites W1983422848 @default.
- W3121059830 cites W1987863203 @default.
- W3121059830 cites W1990496086 @default.
- W3121059830 cites W1998182490 @default.
- W3121059830 cites W1999737340 @default.
- W3121059830 cites W2000737513 @default.
- W3121059830 cites W2001968948 @default.
- W3121059830 cites W2003092321 @default.
- W3121059830 cites W2006563192 @default.
- W3121059830 cites W2009615388 @default.
- W3121059830 cites W2011826792 @default.
- W3121059830 cites W2012073036 @default.
- W3121059830 cites W2012305931 @default.
- W3121059830 cites W2012370414 @default.
- W3121059830 cites W2012915138 @default.
- W3121059830 cites W2013068590 @default.
- W3121059830 cites W2014025848 @default.
- W3121059830 cites W2015410642 @default.
- W3121059830 cites W2015435076 @default.
- W3121059830 cites W2016936614 @default.
- W3121059830 cites W2018670792 @default.
- W3121059830 cites W2023233621 @default.
- W3121059830 cites W2024742943 @default.
- W3121059830 cites W2025493724 @default.
- W3121059830 cites W2028221126 @default.
- W3121059830 cites W2031263609 @default.
- W3121059830 cites W2032195391 @default.
- W3121059830 cites W2034197332 @default.
- W3121059830 cites W2041797419 @default.
- W3121059830 cites W2042307303 @default.
- W3121059830 cites W2042776134 @default.
- W3121059830 cites W2044160465 @default.
- W3121059830 cites W2044399080 @default.
- W3121059830 cites W2045473485 @default.
- W3121059830 cites W2046856408 @default.
- W3121059830 cites W2047239264 @default.
- W3121059830 cites W2047291020 @default.
- W3121059830 cites W2048964714 @default.
- W3121059830 cites W2054331078 @default.
- W3121059830 cites W2054996729 @default.
- W3121059830 cites W2055642130 @default.
- W3121059830 cites W2055741851 @default.
- W3121059830 cites W2058917552 @default.
- W3121059830 cites W2059270746 @default.
- W3121059830 cites W2062928015 @default.
- W3121059830 cites W2063237293 @default.
- W3121059830 cites W2063762582 @default.
- W3121059830 cites W2065142041 @default.
- W3121059830 cites W2065146657 @default.
- W3121059830 cites W2067260112 @default.
- W3121059830 cites W2070798536 @default.
- W3121059830 cites W2072756556 @default.
- W3121059830 cites W2081891572 @default.
- W3121059830 cites W2082462540 @default.
- W3121059830 cites W2082791884 @default.
- W3121059830 cites W2086944159 @default.
- W3121059830 cites W2091701340 @default.
- W3121059830 cites W2091727730 @default.
- W3121059830 cites W2093295969 @default.
- W3121059830 cites W2093908955 @default.
- W3121059830 cites W2094864414 @default.
- W3121059830 cites W2100834477 @default.
- W3121059830 cites W2102941627 @default.
- W3121059830 cites W2104201068 @default.
- W3121059830 cites W2108156699 @default.
- W3121059830 cites W2110673801 @default.
- W3121059830 cites W2112176900 @default.
- W3121059830 cites W2112356750 @default.
- W3121059830 cites W2112901522 @default.
- W3121059830 cites W2117915381 @default.
- W3121059830 cites W2118101243 @default.