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- W3121120147 abstract "Aim: We investigated the prevalence of anti-hepatitis E virus (HEV) antibodies in patients with chronic hepatitis C and the relationship with liver injury stage. Materials & methods: In total, 451 patients were included and the presence of anti-HEV antibodies was evaluated by ELISA. Results: Anti-HEV IgG antibodies were detected in 45 (10.0%) patients and anti-HEV IgM were detected in two IgG-positive patients (4.4%). The distributions of liver fibrosis, steatosis, inflammatory activity, homeostasis model assessment of insulin resistance and liver enzyme levels were similar between HEV-positive and HEV-negative patients. However, HEV-positive patients had a higher mean age (p = 0.030). The seroprevalence by age group increased from 2.2 (18–30 years) to 53.3% (>60 years). HEV infection was not related to advanced fibrosis. Conclusion: This investigation showed that the seroprevalence of HEV among patients with chronic hepatitis C is similar to that of blood donors in the same region." @default.
- W3121120147 created "2021-01-18" @default.
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- W3121120147 date "2020-12-01" @default.
- W3121120147 modified "2023-09-27" @default.
- W3121120147 title "Hepatitis E virus seroprevalence in patients with chronic hepatitis C at a university hospital in Brazil" @default.
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- W3121120147 doi "https://doi.org/10.2217/fvl-2020-0042" @default.
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