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- W3121230503 abstract "Furin is a protease that is ubiquitous in mammalian metabolism. One of the innovations that make SARS-CoV-2 more infectious than its ancestor viruses is addition of a furin cleavage site. Conditions associated with elevated furin, including diabetes, obesity and hypertension, overlap significantly with vulnerability to the severe form of COVID-19. We suggest that diet and lifestyle modifications that reduce the associated comorbidities may prevent the development of severe COVID-19 by, in part, lowering circulating furin. Likewise, natural and pharmaceutical inhibitors of furin may be candidate prophylactic interventions, or if used early in the COVID-19, may prevent the development of critical symptoms." @default.
- W3121230503 created "2021-02-01" @default.
- W3121230503 creator A5085968488 @default.
- W3121230503 date "2020-01-01" @default.
- W3121230503 modified "2023-10-02" @default.
- W3121230503 title "Furin Protease: From SARS CoV‐2 to Anthrax, Diabetes and Hypertension" @default.
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- W3121230503 doi "https://doi.org/10.2139/ssrn.3612934" @default.
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