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• W3121330255 abstract "Abstract BACKGROUND Kidney transplantation is an expensive procedure, and it is an alternative treatment of end-stage renal disease other than dialysis. Cost-Effectiveness and the cost-utility study was undertaken at Sanglah Hospital Bali Indonesia, aiming to assess whether living-related kidney transplantation is more cost-effective and cost-utility than hemodialysis in the treatment of end-stage renal disease. METHODS A health technology assessment was done in living-related kidney transplant and hemodialysis during 2018. Data search from internet resources using the electronic library and critically appraised the best evidence of the data of the best data of five-year mortality and survival of kidney transplant and hemodialysis. A preliminary study about quality of life was also done among kidney transplant and hemodialysis patients. Data about kidney transplant costs and hemodialysis for five years was taken from the Sanglah General Hospital database. RESULTS During the study, Fourteen living-related kidney transplant patients at Sanglah Public Hospital Denpasar Bali Indonesia consisted of 14 recipients, 12 males, and 2 females aged 27 -55 years, and 14 donors, three males and 11 females aged 24-63 years were included. Thirty HEMODIALYSIS patients at the same hospital were recruited. They consisted of 20 males and ten females, with an average age of 50.9 years. The average five-year cost of kidney transplant was 741,078 M IDR. In comparison, hemodialysis's five-year cost was 581,514 M IDR, leading to a cost difference was 159,564 M IDR. Five-year mortality of kidney transplant was 55% (survival 45%), five years survival rate was 18.9%. Five years of survival difference between kidney transplant and hemodialysis was 26.1 %. Meanwhile, QOL for a kidney transplant was 0,7063, and QOL for hemodialysis was 0,5596, leading to a QOL difference of 0.15. Kidney transplantation will spend 6.11 M IDR for every 1% increase of survival for five years with 15% better QOL. In five years, kidney transplantation produces 67% ICER. From cost-utility perspective, kidney transplantation yields 31.04 M IDR per QALY or 2,217 USD per QALY. CONCLUSION Living-related kidney transplantation is more cost-effective and cost-utility than hemodialysis in the treatment of end-stage renal disease." @default.
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• W3121330255 date "2020-11-03" @default.
• W3121330255 modified "2023-10-17" @default.
• W3121330255 title "Health Technology Assessment of Kidney Transplantation and Hemodialysis for the Treatment of End-Stage Kidney Disease" @default.
• W3121330255 doi "https://doi.org/10.21203/rs.3.rs-77471/v1" @default.
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