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- W3121764592 abstract "In the present study, 2-(E)-(N-(4′-alkylazobenzyl)-4-iminoethan-1-yl)-10H-phenothiazine compounds (azobenzyliminophenothiazine), 5–7 have been synthesized and were characterized by FT-IR, 1H&13C NMR, LC-Mass spectral studies. The stable conformer was dug out by DFT calculation using Gaussian-03 W at B3LYP/6-31G(d,p) level. Molecular docking was also performed in order to illustrate the over expression of estrogen receptor in 70% of breast cancers because the azobenzyl could be a scaffold for the exploration of anticancer agents. The compounds 5–7 indicated significant anticancer activity during cytotoxicity study against MCF-7 (Breast cancer) cell line. Further, the evaluated novel series of azobenzyliminophenothiazine compounds 5–7 were exhibited good antioxidant ability in DPPH & ABTS tests." @default.
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- W3121764592 date "2021-01-01" @default.
- W3121764592 modified "2023-09-23" @default.
- W3121764592 title "Design, synthesis, characterization and biological evaluation of some 2-(E)-(N-(azobenzyl)-4-iminoethan-1-yl)-10H-phenothiazines" @default.
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- W3121764592 doi "https://doi.org/10.1016/j.matpr.2020.11.979" @default.
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