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- W3121799650 abstract "The literature data indicate that propolis is distinguished by anti-mutagenic and anti-genotoxic activity. Mutagenicity is characterized by the formation of permanent and hereditary changes in the structure of the genetic material of a cell or organism. However, genotoxicity is associated with the harmful effects of substances on genetic material. To determine the anti-mutagenic and anti-genotoxic effect, a microbiological test using the histidine-dependent Salmonella typhimurium strains (Ames Test) is applied, and in pharmacological studies mutations in mammalian cells and recess mutations in the fruit fly Drosophila melanogaster are determined. A review of the literature indicates that ethanol and aqueous extracts from propolis have got a significant anti-mutagenic and anti-genotoxic influence on many substances that cause mutagenic changes and that damage genetic material. Research indicates that propolis extracts used in therapeutic doses are safe for the human body. Mutagenic and genotoxic effects may only be induced by doses that are many times higher than therapeutic doses, i.e. above 1 g/kg body weight daily." @default.
- W3121799650 created "2021-02-01" @default.
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- W3121799650 date "2020-06-01" @default.
- W3121799650 modified "2023-09-26" @default.
- W3121799650 title "Działanie przeciwmutagenne i przeciwgenotoksyczne propolisu" @default.
- W3121799650 doi "https://doi.org/10.25121/pf.2020.21.2.93" @default.
- W3121799650 hasPublicationYear "2020" @default.
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