Matches in SemOpenAlex for { <https://semopenalex.org/work/W3121948960> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W3121948960 abstract "Background: Capillaria hepatica is a nematode, zoonotic, with worldwide distribution. The main hosts are rodents, nevertheless other mammals can be affected. Although the parasite has high affinity for the liver, it rarely causes a hepatic disease in domestic animals and humans. The diagnosis is difficult and usually a biopsy is required. The treatment is difficult and is based in anti-helminthic and corticoid, but prevention is the best strategy against the disease. The aim of the present report is to describe a case of hepatic capillariosis in a dog approaching the clinical signs, diagnosis and therapeutic. Case: A 12-year-old Brazilian Terrier bitch, with a history of visit to the farm and regular hunting of rats, frogs, birds and other wild animals, was attended with hyporexia and apathy. At the physical exam the dog presented elevation of rectal temperature, intense jaundice and abdominal pain. In the biochemical exams was noticed a slight increase in globulins and a sharp increase in alkaline phosphatase (AP), total, direct and indirect bilirubin, suggesting a liver injury. In the ultrasonographic exam, hepatomegaly with dispersed hyperechoic areas were observed, suggesting hepatic steatosis. The patient was treated with ursodesoxicolic acid and S-adenosil metionin for 30 consecutive days, showing a clinic improvement. Two months after the end of the treatment the animal worsened, showing jaundice, ascites, motor incoordination, weakness, difficulty in food and water ingestion and changes in the mental state. In the complete blood count was observed a macrocytic hypochromic regenerative anemia, leukocytosis with neutrophilia and monocytosis and thrombocytopenia. In biochemical exams was detected decrease in creatinine and albumin and increase in alanine aminotransferase and AP, suggesting hepatopathy by biliary obstruction. There were performed exams for leishmania and ehrlichiosis that tested negative. In the ultrasonographic exam it was noticed that the liver had the same alterations and the presence of free fluid in the abdominal cavity. Due to the deterioration of the clinical picture a blood transfusion was necessary, however the patient worsened and presented respiratory difficulty for a bilateral pleural effusion. Then, the fluid was drained and a treatment with S-adenosil metionin, silymarin, ursodesoxicolic acid, doxycycline and prednisolone was started. After 17 days, a hepatic biopsy was performed, but the patient died at the surgery desk. Samples from the liver were collected for histopathologic exam. The diagnosis was confirmed in hepatic capillariosis and periportal chronic hepatitis, with the visualization of numerous parasites structures with bioperculated barrel shape. Discussion: Due to the nonspecific clinical alterations observed in the patient and the low prevalence of C. hepatica in domestic animals, there was a difficulty in the diagnosis which lead to a symptomatic, nonspecific and inefficient treatment that culminate with the death of the patient. The histopathologic exam of the liver is the best manner to find the correct diagnosis of C. hepatica infection, once the parasites eggs remains in the liver parenchyma wrapped by fibrosis and aren´t eliminate in the feces. The eggs elimination in the environment just occur after the death of the animal. Although there didn't exist a consensus about hepatic capillariosis treatment yet, if the diagnosis were done earlier, a specific treatment with better chances of a good result could be performed. We concluded that hepatic capillariosis should be included in differential diagnosis for patients with hepatic syndrome, mainly if the animal had a hunting habit and if it had access to surroundings with high rats’ infestation." @default.
- W3121948960 created "2021-02-01" @default.
- W3121948960 creator A5001212410 @default.
- W3121948960 creator A5006252567 @default.
- W3121948960 creator A5030830656 @default.
- W3121948960 creator A5035728973 @default.
- W3121948960 creator A5038126785 @default.
- W3121948960 creator A5068811073 @default.
- W3121948960 creator A5088371622 @default.
- W3121948960 date "2021-02-05" @default.
- W3121948960 modified "2023-10-15" @default.
- W3121948960 title "True Infection by Capillaria hepatica in a Dog" @default.
- W3121948960 cites W1525955553 @default.
- W3121948960 cites W1966980963 @default.
- W3121948960 cites W1978564550 @default.
- W3121948960 cites W1983635914 @default.
- W3121948960 cites W1991155198 @default.
- W3121948960 cites W2011252978 @default.
- W3121948960 cites W2037219286 @default.
- W3121948960 cites W2053581179 @default.
- W3121948960 cites W2107925526 @default.
- W3121948960 cites W2126961401 @default.
- W3121948960 cites W2135334191 @default.
- W3121948960 cites W2136650760 @default.
- W3121948960 cites W2336930617 @default.
- W3121948960 cites W2397379961 @default.
- W3121948960 cites W2581299916 @default.
- W3121948960 doi "https://doi.org/10.22456/1679-9216.106696" @default.
- W3121948960 hasPublicationYear "2021" @default.
- W3121948960 type Work @default.
- W3121948960 sameAs 3121948960 @default.
- W3121948960 citedByCount "1" @default.
- W3121948960 countsByYear W31219489602022 @default.
- W3121948960 crossrefType "journal-article" @default.
- W3121948960 hasAuthorship W3121948960A5001212410 @default.
- W3121948960 hasAuthorship W3121948960A5006252567 @default.
- W3121948960 hasAuthorship W3121948960A5030830656 @default.
- W3121948960 hasAuthorship W3121948960A5035728973 @default.
- W3121948960 hasAuthorship W3121948960A5038126785 @default.
- W3121948960 hasAuthorship W3121948960A5068811073 @default.
- W3121948960 hasAuthorship W3121948960A5088371622 @default.
- W3121948960 hasBestOaLocation W31219489601 @default.
- W3121948960 hasConcept C126322002 @default.
- W3121948960 hasConcept C142724271 @default.
- W3121948960 hasConcept C165901193 @default.
- W3121948960 hasConcept C203014093 @default.
- W3121948960 hasConcept C2777119230 @default.
- W3121948960 hasConcept C2777802486 @default.
- W3121948960 hasConcept C2778456037 @default.
- W3121948960 hasConcept C2778923028 @default.
- W3121948960 hasConcept C2780007613 @default.
- W3121948960 hasConcept C2781087989 @default.
- W3121948960 hasConcept C42407357 @default.
- W3121948960 hasConcept C71924100 @default.
- W3121948960 hasConcept C86803240 @default.
- W3121948960 hasConcept C90924648 @default.
- W3121948960 hasConceptScore W3121948960C126322002 @default.
- W3121948960 hasConceptScore W3121948960C142724271 @default.
- W3121948960 hasConceptScore W3121948960C165901193 @default.
- W3121948960 hasConceptScore W3121948960C203014093 @default.
- W3121948960 hasConceptScore W3121948960C2777119230 @default.
- W3121948960 hasConceptScore W3121948960C2777802486 @default.
- W3121948960 hasConceptScore W3121948960C2778456037 @default.
- W3121948960 hasConceptScore W3121948960C2778923028 @default.
- W3121948960 hasConceptScore W3121948960C2780007613 @default.
- W3121948960 hasConceptScore W3121948960C2781087989 @default.
- W3121948960 hasConceptScore W3121948960C42407357 @default.
- W3121948960 hasConceptScore W3121948960C71924100 @default.
- W3121948960 hasConceptScore W3121948960C86803240 @default.
- W3121948960 hasConceptScore W3121948960C90924648 @default.
- W3121948960 hasLocation W31219489601 @default.
- W3121948960 hasOpenAccess W3121948960 @default.
- W3121948960 hasPrimaryLocation W31219489601 @default.
- W3121948960 hasRelatedWork W10715090 @default.
- W3121948960 hasRelatedWork W11809007 @default.
- W3121948960 hasRelatedWork W12081155 @default.
- W3121948960 hasRelatedWork W12296056 @default.
- W3121948960 hasRelatedWork W13500216 @default.
- W3121948960 hasRelatedWork W13925891 @default.
- W3121948960 hasRelatedWork W4909274 @default.
- W3121948960 hasRelatedWork W6173846 @default.
- W3121948960 hasRelatedWork W9436669 @default.
- W3121948960 hasRelatedWork W3927098 @default.
- W3121948960 isParatext "false" @default.
- W3121948960 isRetracted "false" @default.
- W3121948960 magId "3121948960" @default.
- W3121948960 workType "article" @default.