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- W3121951569 abstract "Oral route is one of the most extensively used routes for drug administration for several advantages. In conventional oral drug delivery system, the release rate of drug cannot be controlled and effective concentration at the target site achieved is low. Bioavailability of drugs from the oral drug delivery may vary significantly, depending on factors such as physicochemical properties of the drug, presence of excipients, various physiological factors such as the presence or absence of food, pH of GIT, GI motility. OROS is an advanced drug delivery system that uses osmotic pressure as a driving force to deliver drug in a controlled manner for a longer period of time. In this review article, historical aspects related to osmotic pump, various types of osmotically controlled pumps like EOP, PPOS, CPOP, etc. have been studied. The basic components which are required for developing an oral osmotically controlled release formulations and factors affecting on release characteristics drug from an osmotic system have been discussed briefly." @default.
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- W3121951569 date "2020-10-01" @default.
- W3121951569 modified "2023-09-22" @default.
- W3121951569 title "A Comprehensive Review On Osmotically Controlled Oral Drug Delivery System" @default.
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