FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3122022366> ?p ?o ?g. }

• W3122022366 endingPage "1022" @default.
• W3122022366 startingPage "1012" @default.
• W3122022366 abstract "Impairments in inhibitory control and its underlying brain networks (control/salience areas) are associated with substance misuse. Research often assumes a causal substance exposure effect on brain structure. This assumption remains largely untested, and other factors (e.g., familial risk) may confound exposure effects. We leveraged a genetically informative sample of twins aged 24 years and a quasi-experimental co-twin control design to separate alcohol or cannabis exposure effects during emerging adulthood from familial risk on control/salience network cortical thickness.In a population-based sample of 436 twins aged 24 years, dimensional measures of alcohol and cannabis use (e.g., frequency, density, quantity, intoxications) across emerging adulthood were assessed. Cortical thickness of control/salience network areas were assessed using magnetic resonance imaging and defined by a fine-grained cortical atlas.Greater alcohol, but not cannabis, misuse was associated with reduced thickness of prefrontal (e.g., dorso/ventrolateral, right frontal operculum) and frontal medial cortices, as well as temporal lobe, intraparietal sulcus, insula, parietal operculum, precuneus, and parietal medial areas. Effects were predominately (pre)frontal and right lateralized. Co-twin control analyses suggested that the effects likely reflect both the familial predisposition to misuse alcohol and, specifically for lateral prefrontal, frontal/parietal medial, and right frontal operculum, an alcohol exposure effect.This study provides novel evidence that alcohol-related reductions in cortical thickness of control/salience brain networks likely represent the effects of alcohol exposure and premorbid characteristics of the genetic predisposition to misuse alcohol. The dual effects of these two alcohol-related causal influences have important and complementary implications regarding public health and prevention efforts to curb youth drinking." @default.
• W3122022366 created "2021-02-01" @default.
• W3122022366 creator A5012933125 @default.
• W3122022366 creator A5024802867 @default.
• W3122022366 creator A5026726602 @default.
• W3122022366 creator A5027078385 @default.
• W3122022366 creator A5039999379 @default.
• W3122022366 creator A5080679639 @default.
• W3122022366 date "2021-05-01" @default.
• W3122022366 modified "2023-10-18" @default.
• W3122022366 title "The Effects of Alcohol and Cannabis Use on the Cortical Thickness of Cognitive Control and Salience Brain Networks in Emerging Adulthood: A Co-twin Control Study" @default.
• W3122022366 cites W1042512276 @default.
• W3122022366 cites W1489882924 @default.
• W3122022366 cites W1515859801 @default.
• W3122022366 cites W1561567566 @default.
• W3122022366 cites W1922885165 @default.
• W3122022366 cites W1936785944 @default.
• W3122022366 cites W1964895626 @default.
• W3122022366 cites W1969100427 @default.
• W3122022366 cites W1972039452 @default.
• W3122022366 cites W1982910299 @default.
• W3122022366 cites W1991911667 @default.
• W3122022366 cites W1998733518 @default.
• W3122022366 cites W2000998192 @default.
• W3122022366 cites W2002256171 @default.
• W3122022366 cites W2004293194 @default.
• W3122022366 cites W2004639043 @default.
• W3122022366 cites W2005476331 @default.
• W3122022366 cites W2012801579 @default.
• W3122022366 cites W2013859768 @default.
• W3122022366 cites W2021852270 @default.
• W3122022366 cites W2024702358 @default.
• W3122022366 cites W2030055333 @default.
• W3122022366 cites W2037689983 @default.
• W3122022366 cites W2039169553 @default.
• W3122022366 cites W2047903753 @default.
• W3122022366 cites W2066848874 @default.
• W3122022366 cites W2067456724 @default.
• W3122022366 cites W2078530990 @default.
• W3122022366 cites W2093438567 @default.
• W3122022366 cites W2095491799 @default.
• W3122022366 cites W2101135654 @default.
• W3122022366 cites W2106923624 @default.
• W3122022366 cites W2113758413 @default.
• W3122022366 cites W2125905177 @default.
• W3122022366 cites W2144177438 @default.
• W3122022366 cites W2146738944 @default.
• W3122022366 cites W2148398483 @default.
• W3122022366 cites W2149331480 @default.
• W3122022366 cites W2151130155 @default.
• W3122022366 cites W2156430527 @default.
• W3122022366 cites W2156539308 @default.
• W3122022366 cites W2158197715 @default.
• W3122022366 cites W2159594385 @default.
• W3122022366 cites W2160694463 @default.
• W3122022366 cites W2166756161 @default.
• W3122022366 cites W2167785125 @default.
• W3122022366 cites W2169351667 @default.
• W3122022366 cites W2172297581 @default.
• W3122022366 cites W2286968510 @default.
• W3122022366 cites W2295982294 @default.
• W3122022366 cites W2412496260 @default.
• W3122022366 cites W2495861132 @default.
• W3122022366 cites W2500239696 @default.
• W3122022366 cites W2551283762 @default.
• W3122022366 cites W2620631827 @default.
• W3122022366 cites W2649063040 @default.
• W3122022366 cites W2744192774 @default.
• W3122022366 cites W2756017281 @default.
• W3122022366 cites W2765624956 @default.
• W3122022366 cites W2765939349 @default.
• W3122022366 cites W2766873368 @default.
• W3122022366 cites W2767301703 @default.
• W3122022366 cites W2806175929 @default.
• W3122022366 cites W2806922534 @default.
• W3122022366 cites W2895503081 @default.
• W3122022366 cites W2895898846 @default.
• W3122022366 cites W2897774008 @default.
• W3122022366 cites W2907530472 @default.
• W3122022366 cites W2928966425 @default.
• W3122022366 cites W2929067594 @default.
• W3122022366 cites W2951617899 @default.
• W3122022366 cites W2973172566 @default.
• W3122022366 cites W2976732385 @default.
• W3122022366 cites W2986756902 @default.
• W3122022366 cites W3102070981 @default.
• W3122022366 cites W4295750005 @default.
• W3122022366 doi "https://doi.org/10.1016/j.biopsych.2021.01.006" @default.
• W3122022366 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8106644" @default.
• W3122022366 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33726938" @default.
• W3122022366 hasPublicationYear "2021" @default.
• W3122022366 type Work @default.
• W3122022366 sameAs 3122022366 @default.
• W3122022366 citedByCount "14" @default.
• W3122022366 countsByYear W31220223662021 @default.
• W3122022366 countsByYear W31220223662022 @default.
• W3122022366 countsByYear W31220223662023 @default.
• W3122022366 crossrefType "journal-article" @default.

• next