FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3122246237> ?p ?o ?g. }

• W3122246237 endingPage "129" @default.
• W3122246237 startingPage "129" @default.
• W3122246237 abstract "The assembly of a hexameric lattice of retroviral immature particles requires the involvement of cell factors such as proteins and small molecules. A small, negatively charged polyanionic molecule, myo-inositol hexaphosphate (IP6), was identified to stimulate the assembly of immature particles of HIV-1 and other lentiviruses. Interestingly, cryo-electron tomography analysis of the immature particles of two lentiviruses, HIV-1 and equine infectious anemia virus (EIAV), revealed that the IP6 binding site is similar. Based on this amino acid conservation of the IP6 interacting site, it is presumed that the assembly of immature particles of all lentiviruses is stimulated by IP6. Although this specific region for IP6 binding may be unique for lentiviruses, it is plausible that other retroviral species also recruit some small polyanion to facilitate the assembly of their immature particles. To study whether the assembly of retroviruses other than lentiviruses can be stimulated by polyanionic molecules, we measured the effect of various polyanions on the assembly of immature virus-like particles of Rous sarcoma virus (RSV), a member of alpharetroviruses, Mason-Pfizer monkey virus (M-PMV) representative of betaretroviruses, and murine leukemia virus (MLV), a member of gammaretroviruses. RSV, M-PMV and MLV immature virus-like particles were assembled in vitro from truncated Gag molecules and the effect of selected polyanions, myo-inostol hexaphosphate, myo-inositol, glucose-1,6-bisphosphate, myo-inositol hexasulphate, and mellitic acid, on the particles assembly was quantified. Our results suggest that the assembly of immature particles of RSV and MLV was indeed stimulated by the presence of myo-inostol hexaphosphate and myo-inositol, respectively. In contrast, no effect on the assembly of M-PMV as a betaretrovirus member was observed." @default.
• W3122246237 created "2021-02-01" @default.
• W3122246237 creator A5018966052 @default.
• W3122246237 creator A5054068890 @default.
• W3122246237 creator A5057667007 @default.
• W3122246237 creator A5066258131 @default.
• W3122246237 creator A5082313921 @default.
• W3122246237 creator A5087932955 @default.
• W3122246237 date "2021-01-18" @default.
• W3122246237 modified "2023-09-27" @default.
• W3122246237 title "Effect of Small Polyanions on In Vitro Assembly of Selected Members of Alpha-, Beta- and Gammaretroviruses" @default.
• W3122246237 cites W1562103219 @default.
• W3122246237 cites W1574899039 @default.
• W3122246237 cites W1575815180 @default.
• W3122246237 cites W1579191879 @default.
• W3122246237 cites W1924577704 @default.
• W3122246237 cites W1933776452 @default.
• W3122246237 cites W1964052712 @default.
• W3122246237 cites W1989767992 @default.
• W3122246237 cites W1994410560 @default.
• W3122246237 cites W1995334678 @default.
• W3122246237 cites W1997860232 @default.
• W3122246237 cites W1997940831 @default.
• W3122246237 cites W2001070158 @default.
• W3122246237 cites W2021837455 @default.
• W3122246237 cites W2028156315 @default.
• W3122246237 cites W2033236966 @default.
• W3122246237 cites W2038737274 @default.
• W3122246237 cites W2041950326 @default.
• W3122246237 cites W2042938599 @default.
• W3122246237 cites W2045028231 @default.
• W3122246237 cites W2057712924 @default.
• W3122246237 cites W2057723413 @default.
• W3122246237 cites W2062334646 @default.
• W3122246237 cites W2068446921 @default.
• W3122246237 cites W2072980373 @default.
• W3122246237 cites W2074560169 @default.
• W3122246237 cites W2077087259 @default.
• W3122246237 cites W2077697876 @default.
• W3122246237 cites W2087978946 @default.
• W3122246237 cites W2105093369 @default.
• W3122246237 cites W2106298056 @default.
• W3122246237 cites W2107120241 @default.
• W3122246237 cites W2112535691 @default.
• W3122246237 cites W2115382947 @default.
• W3122246237 cites W2131122524 @default.
• W3122246237 cites W2132913838 @default.
• W3122246237 cites W2137401529 @default.
• W3122246237 cites W2146024897 @default.
• W3122246237 cites W2147792469 @default.
• W3122246237 cites W2151131547 @default.
• W3122246237 cites W2152539875 @default.
• W3122246237 cites W2277875601 @default.
• W3122246237 cites W2466725324 @default.
• W3122246237 cites W2515757111 @default.
• W3122246237 cites W27696673 @default.
• W3122246237 cites W2886259097 @default.
• W3122246237 cites W3000717531 @default.
• W3122246237 cites W3045584868 @default.
• W3122246237 cites W4248668370 @default.
• W3122246237 cites W4249774679 @default.
• W3122246237 doi "https://doi.org/10.3390/v13010129" @default.
• W3122246237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7831069" @default.
• W3122246237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33477490" @default.
• W3122246237 hasPublicationYear "2021" @default.
• W3122246237 type Work @default.
• W3122246237 sameAs 3122246237 @default.
• W3122246237 citedByCount "4" @default.
• W3122246237 countsByYear W31222462372021 @default.
• W3122246237 countsByYear W31222462372023 @default.
• W3122246237 crossrefType "journal-article" @default.
• W3122246237 hasAuthorship W3122246237A5018966052 @default.
• W3122246237 hasAuthorship W3122246237A5054068890 @default.
• W3122246237 hasAuthorship W3122246237A5057667007 @default.
• W3122246237 hasAuthorship W3122246237A5066258131 @default.
• W3122246237 hasAuthorship W3122246237A5082313921 @default.
• W3122246237 hasAuthorship W3122246237A5087932955 @default.
• W3122246237 hasBestOaLocation W31222462371 @default.
• W3122246237 hasConcept C104317684 @default.
• W3122246237 hasConcept C153911025 @default.
• W3122246237 hasConcept C159047783 @default.
• W3122246237 hasConcept C185592680 @default.
• W3122246237 hasConcept C202751555 @default.
• W3122246237 hasConcept C2522874641 @default.
• W3122246237 hasConcept C2776387124 @default.
• W3122246237 hasConcept C2777441520 @default.
• W3122246237 hasConcept C2779562191 @default.
• W3122246237 hasConcept C2779690655 @default.
• W3122246237 hasConcept C2780727368 @default.
• W3122246237 hasConcept C2781053568 @default.
• W3122246237 hasConcept C40767141 @default.
• W3122246237 hasConcept C55493867 @default.
• W3122246237 hasConcept C86803240 @default.
• W3122246237 hasConcept C95444343 @default.
• W3122246237 hasConceptScore W3122246237C104317684 @default.
• W3122246237 hasConceptScore W3122246237C153911025 @default.
• W3122246237 hasConceptScore W3122246237C159047783 @default.
• W3122246237 hasConceptScore W3122246237C185592680 @default.

• next