Matches in SemOpenAlex for { <https://semopenalex.org/work/W3122281310> ?p ?o ?g. }
- W3122281310 endingPage "e06033" @default.
- W3122281310 startingPage "e06033" @default.
- W3122281310 abstract "A ubiquitous component of cell membrane, phosphatidylserine (PS), is likely to play a major, but as yet unrecognized, role in the thromboinflammation of COVID-19 and other critical illnesses. PS is present in all plasma membranes but is “hidden” on the inner surface by the action of an ATP-requiring enzyme. Failure of PS to be sequestered on the inner surface of cell membranes, release of PS-containing microparticles from cells, or shedding of enveloped viruses allows it to interact with extracellular proteins, including those of the coagulation and complement systems. Detection and quantification of circulating PS is not standardized, and current methodologies have either focused on circulating cellular elements or subcellular plasma components, but not both. PS may also promote thromboinflammation without circulating if expressed on the surface of endothelial cells, a condition that might only be documented if novel imaging techniques are developed. Research into the role of PS in inflammation and coagulation, called here a “procoagulant phospholipidopathy” may provide novel insights and therapeutic approaches for patients with a variety of illnesses." @default.
- W3122281310 created "2021-02-01" @default.
- W3122281310 creator A5001123822 @default.
- W3122281310 date "2021-01-01" @default.
- W3122281310 modified "2023-10-10" @default.
- W3122281310 title "Phosphatidylserine is an overlooked mediator of COVID-19 thromboinflammation" @default.
- W3122281310 cites W1493824599 @default.
- W3122281310 cites W1549348777 @default.
- W3122281310 cites W1963522651 @default.
- W3122281310 cites W1964061344 @default.
- W3122281310 cites W1977538788 @default.
- W3122281310 cites W1981955271 @default.
- W3122281310 cites W1982205775 @default.
- W3122281310 cites W1988034658 @default.
- W3122281310 cites W1995472148 @default.
- W3122281310 cites W1996192057 @default.
- W3122281310 cites W2006328610 @default.
- W3122281310 cites W2008483588 @default.
- W3122281310 cites W2011839942 @default.
- W3122281310 cites W2021637137 @default.
- W3122281310 cites W2022177860 @default.
- W3122281310 cites W2030383998 @default.
- W3122281310 cites W2037550744 @default.
- W3122281310 cites W2046351754 @default.
- W3122281310 cites W2048741161 @default.
- W3122281310 cites W2058172582 @default.
- W3122281310 cites W2058501337 @default.
- W3122281310 cites W2062828619 @default.
- W3122281310 cites W2065089988 @default.
- W3122281310 cites W2069501274 @default.
- W3122281310 cites W2072592047 @default.
- W3122281310 cites W2078541138 @default.
- W3122281310 cites W2099133435 @default.
- W3122281310 cites W2127911548 @default.
- W3122281310 cites W2147698308 @default.
- W3122281310 cites W2160056300 @default.
- W3122281310 cites W2171199984 @default.
- W3122281310 cites W2227516281 @default.
- W3122281310 cites W2265596957 @default.
- W3122281310 cites W2301508931 @default.
- W3122281310 cites W2324183272 @default.
- W3122281310 cites W2516370793 @default.
- W3122281310 cites W2521450141 @default.
- W3122281310 cites W2552356858 @default.
- W3122281310 cites W2562235028 @default.
- W3122281310 cites W2725377209 @default.
- W3122281310 cites W2770735953 @default.
- W3122281310 cites W2801375169 @default.
- W3122281310 cites W2911093128 @default.
- W3122281310 cites W2954661041 @default.
- W3122281310 cites W2972169641 @default.
- W3122281310 cites W2982420668 @default.
- W3122281310 cites W2982506976 @default.
- W3122281310 cites W3009747115 @default.
- W3122281310 cites W3016123694 @default.
- W3122281310 cites W3017125154 @default.
- W3122281310 cites W3018794620 @default.
- W3122281310 cites W3027918021 @default.
- W3122281310 cites W3028615142 @default.
- W3122281310 cites W3028989873 @default.
- W3122281310 cites W3030604488 @default.
- W3122281310 cites W3033382435 @default.
- W3122281310 cites W3038529733 @default.
- W3122281310 cites W3041608326 @default.
- W3122281310 cites W3048032171 @default.
- W3122281310 cites W3092241378 @default.
- W3122281310 cites W3111602251 @default.
- W3122281310 doi "https://doi.org/10.1016/j.heliyon.2021.e06033" @default.
- W3122281310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7817455" @default.
- W3122281310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33495740" @default.
- W3122281310 hasPublicationYear "2021" @default.
- W3122281310 type Work @default.
- W3122281310 sameAs 3122281310 @default.
- W3122281310 citedByCount "13" @default.
- W3122281310 countsByYear W31222813102021 @default.
- W3122281310 countsByYear W31222813102022 @default.
- W3122281310 countsByYear W31222813102023 @default.
- W3122281310 crossrefType "journal-article" @default.
- W3122281310 hasAuthorship W3122281310A5001123822 @default.
- W3122281310 hasBestOaLocation W31222813101 @default.
- W3122281310 hasConcept C118552586 @default.
- W3122281310 hasConcept C12554922 @default.
- W3122281310 hasConcept C1491633281 @default.
- W3122281310 hasConcept C185592680 @default.
- W3122281310 hasConcept C203014093 @default.
- W3122281310 hasConcept C2107291 @default.
- W3122281310 hasConcept C2776914184 @default.
- W3122281310 hasConcept C2778106830 @default.
- W3122281310 hasConcept C2778382381 @default.
- W3122281310 hasConcept C2778918659 @default.
- W3122281310 hasConcept C2779637612 @default.
- W3122281310 hasConcept C28406088 @default.
- W3122281310 hasConcept C41625074 @default.
- W3122281310 hasConcept C55493867 @default.
- W3122281310 hasConcept C71924100 @default.
- W3122281310 hasConcept C86803240 @default.
- W3122281310 hasConcept C95444343 @default.
- W3122281310 hasConceptScore W3122281310C118552586 @default.