Matches in SemOpenAlex for { <https://semopenalex.org/work/W3122631623> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W3122631623 abstract "Major depressive disorder (MDD) is a debilitating mental health condition that affects people of all ages, leading to significant negative impact on functional status, quality of life, productivity, risk of suicide and health care costs. Based on data from a 2012 survey of the Canadian Community Health Study-Mental Health, the prevalence of MDD in Canada was 3.9%, with two-thirds of which sought treatment. Patients with MDD are first treated with various antidepressants. However, less than 50% of patients with MDD do not achieve adequate response or remission under first line antidepressant therapy.Second-generation antipsychotics or atypical antipsychotics, including quetiapine, aripiprazole, brexpiprazole and olanzapine have been approved as add-on treatment to antidepressant therapy. In Canada, quetiapine extended release (XR) under the brand name of Seroquel XR by AstraZeneca received the approval for treatment of MDD in patients who have failed previous antidepressant treatment due to a lack of efficacy and/or lack of tolerability. Adverse events associated with quetiapine use includes somnolence, sedation, weight gain, extrapyramidal symptoms, and abnormal laboratory results related to glucose, thyroid and cholesterol metabolism. It remains uncertain whether the benefits outweigh the risks of adjunctive treatment with quetiapine for MDD.The aim of this report is to review the comparative clinical effectiveness and cost-effectiveness of quetiapine versus other competing interventions such as typical antipsychotics, other atypical antipsychotics, lithium, lamotrigine, and antidepressants for the treatment of adults with MDD. This report also aims to identify evidence-based guidelines regarding the use of quetiapine for MDD." @default.
- W3122631623 created "2021-02-01" @default.
- W3122631623 creator A5034366374 @default.
- W3122631623 creator A5035012421 @default.
- W3122631623 date "2020-01-30" @default.
- W3122631623 modified "2023-09-27" @default.
- W3122631623 title "Quetiapine for Major Depressive Disorder: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet]" @default.
- W3122631623 hasPublicationYear "2020" @default.
- W3122631623 type Work @default.
- W3122631623 sameAs 3122631623 @default.
- W3122631623 citedByCount "0" @default.
- W3122631623 crossrefType "journal-article" @default.
- W3122631623 hasAuthorship W3122631623A5034366374 @default.
- W3122631623 hasAuthorship W3122631623A5035012421 @default.
- W3122631623 hasConcept C118552586 @default.
- W3122631623 hasConcept C126322002 @default.
- W3122631623 hasConcept C197934379 @default.
- W3122631623 hasConcept C2776412080 @default.
- W3122631623 hasConcept C2776619155 @default.
- W3122631623 hasConcept C2776921671 @default.
- W3122631623 hasConcept C2778375690 @default.
- W3122631623 hasConcept C2779177272 @default.
- W3122631623 hasConcept C2780051608 @default.
- W3122631623 hasConcept C2780211496 @default.
- W3122631623 hasConcept C2780494398 @default.
- W3122631623 hasConcept C2780634440 @default.
- W3122631623 hasConcept C2780733359 @default.
- W3122631623 hasConcept C2911140283 @default.
- W3122631623 hasConcept C558461103 @default.
- W3122631623 hasConcept C71924100 @default.
- W3122631623 hasConceptScore W3122631623C118552586 @default.
- W3122631623 hasConceptScore W3122631623C126322002 @default.
- W3122631623 hasConceptScore W3122631623C197934379 @default.
- W3122631623 hasConceptScore W3122631623C2776412080 @default.
- W3122631623 hasConceptScore W3122631623C2776619155 @default.
- W3122631623 hasConceptScore W3122631623C2776921671 @default.
- W3122631623 hasConceptScore W3122631623C2778375690 @default.
- W3122631623 hasConceptScore W3122631623C2779177272 @default.
- W3122631623 hasConceptScore W3122631623C2780051608 @default.
- W3122631623 hasConceptScore W3122631623C2780211496 @default.
- W3122631623 hasConceptScore W3122631623C2780494398 @default.
- W3122631623 hasConceptScore W3122631623C2780634440 @default.
- W3122631623 hasConceptScore W3122631623C2780733359 @default.
- W3122631623 hasConceptScore W3122631623C2911140283 @default.
- W3122631623 hasConceptScore W3122631623C558461103 @default.
- W3122631623 hasConceptScore W3122631623C71924100 @default.
- W3122631623 hasLocation W31226316231 @default.
- W3122631623 hasOpenAccess W3122631623 @default.
- W3122631623 hasPrimaryLocation W31226316231 @default.
- W3122631623 hasRelatedWork W1575205547 @default.
- W3122631623 hasRelatedWork W159401344 @default.
- W3122631623 hasRelatedWork W2015918717 @default.
- W3122631623 hasRelatedWork W2022024713 @default.
- W3122631623 hasRelatedWork W2030345783 @default.
- W3122631623 hasRelatedWork W2051431297 @default.
- W3122631623 hasRelatedWork W2054589128 @default.
- W3122631623 hasRelatedWork W2064346475 @default.
- W3122631623 hasRelatedWork W2077311215 @default.
- W3122631623 hasRelatedWork W2100162047 @default.
- W3122631623 hasRelatedWork W2128433422 @default.
- W3122631623 hasRelatedWork W2146527338 @default.
- W3122631623 hasRelatedWork W2154926205 @default.
- W3122631623 hasRelatedWork W2526466306 @default.
- W3122631623 hasRelatedWork W3004470393 @default.
- W3122631623 hasRelatedWork W3033447508 @default.
- W3122631623 hasRelatedWork W3121460041 @default.
- W3122631623 hasRelatedWork W313488173 @default.
- W3122631623 hasRelatedWork W3210521464 @default.
- W3122631623 hasRelatedWork W2071410273 @default.
- W3122631623 isParatext "false" @default.
- W3122631623 isRetracted "false" @default.
- W3122631623 magId "3122631623" @default.
- W3122631623 workType "article" @default.