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• W3122741300 abstract "Crossover events along chromosomes do not occur independently, but influence the probably of other nearby events. The most common interaction between nearby crossover events is inhibitory:enskip a crossover event tends to reduce the probability of other such events nearby, and this is called positive interference. Although it occurs rarely, a crossover event may increase the probability of events nearby, and this is called negative interference. In this paper, we use numerical methods to investigate how interference among three loci would evolve if it were under the genetic control of a fourth, selectively neutral locus. We first discuss the effect of interference on the overall rate of recombination among the three loci, and then show that, under a variety of conditions, interference evolves in the same way as would be predicted based upon its effect on the overall rate of recombination. That is, the overall rate evolves in the same direction as would the rate at a locus that controls recombination between two loci directly. We then check for the existence of viability analogous Hardy-Weinberg equilibria in the four-locus model of interference modification." @default.
• W3122741300 created "2021-02-01" @default.
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• W3122741300 date "1993-03-01" @default.
• W3122741300 modified "2023-09-27" @default.
• W3122741300 title "The Evolution of Interface: Reduction of Recombination Among Three Loci" @default.
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• W3122741300 hasPublicationYear "1993" @default.
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