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- W3122912123 abstract "A 52-year-old woman with a BMI of 31.2 kg/m2 was treated with the glucagon-like peptide 1 (GLP-1) agonist liraglutide as part of her weight-reduction program. Following this, she developed an idiosyncratic drug-related liver injury (IDILI). Advances in noninvasive techniques enabled this diagnosis to be established. By employing easily quantifiable methods based on serum biomarkers, we could explore a wide variety of endpoints in assessing personalized DILI. In addition, we can test endpoints that are associated with the drug’s mechanism of action. Personalized medicine and therapeutic pharmacovigilance of incretin-based hypoglycemic agents are needed to ensure the safety of patients." @default.
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- W3122912123 date "2021-01-22" @default.
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- W3122912123 title "Liraglutide-Induced Hepatotoxicity" @default.
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- W3122912123 doi "https://doi.org/10.3390/biomedicines9020106" @default.
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