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• W3122912182 abstract "Essential hypertension (EH) is one of the most common cardiovascular diseases worldwide, entailing a high level of morbidity. EH is a multifactorial disease influenced by both genetic and environmental factors, including mitochondrial DNA (mtDNA) genotype. Previous studies identified mtDNA mutations that are associated with maternally inherited hypertension, including tRNAIle m.4263A>G, m.4291T>C, m.4295A>G, tRNAMet m.4435A>G, tRNAAla m.5655A>G, and tRNAMet/tRNAGln m.4401A>G, et al. These mtDNA mutations alter tRNA structure, thereby leading to metabolic disorders. Metabolic defects associated with mitochondrial tRNAs affect protein synthesis, cause oxidative phosphorylation defects, reduced ATP synthesis, and increase production of reactive oxygen species. In this review we discuss known mutations of tRNA genes encoded by mtDNA and the potential mechanisms by which these mutations may contribute to hypertension." @default.
• W3122912182 created "2021-02-01" @default.
• W3122912182 creator A5051858597 @default.
• W3122912182 creator A5084136821 @default.
• W3122912182 date "2021-01-22" @default.
• W3122912182 modified "2023-09-27" @default.
• W3122912182 title "Mitochondrial tRNA Mutations Associated With Essential Hypertension: From Molecular Genetics to Function" @default.
• W3122912182 cites W1593732853 @default.
• W3122912182 cites W1617208156 @default.
• W3122912182 cites W1744896556 @default.
• W3122912182 cites W1761933721 @default.
• W3122912182 cites W1781872636 @default.
• W3122912182 cites W1968197570 @default.
• W3122912182 cites W1970078691 @default.
• W3122912182 cites W1971723295 @default.
• W3122912182 cites W1972925152 @default.
• W3122912182 cites W1973880725 @default.
• W3122912182 cites W1978490949 @default.
• W3122912182 cites W1979111973 @default.
• W3122912182 cites W1987127105 @default.
• W3122912182 cites W1990936904 @default.
• W3122912182 cites W1995362888 @default.
• W3122912182 cites W1996067374 @default.
• W3122912182 cites W1998262675 @default.
• W3122912182 cites W2007122274 @default.
• W3122912182 cites W2007761300 @default.
• W3122912182 cites W2008224500 @default.
• W3122912182 cites W2011493287 @default.
• W3122912182 cites W2013310162 @default.
• W3122912182 cites W2014901923 @default.
• W3122912182 cites W2021674095 @default.
• W3122912182 cites W2029395446 @default.
• W3122912182 cites W2033645952 @default.
• W3122912182 cites W2034862605 @default.
• W3122912182 cites W2036951068 @default.
• W3122912182 cites W2039307902 @default.
• W3122912182 cites W2042002091 @default.
• W3122912182 cites W2042120426 @default.
• W3122912182 cites W2042965442 @default.
• W3122912182 cites W2044221417 @default.
• W3122912182 cites W2044494908 @default.
• W3122912182 cites W2047102154 @default.
• W3122912182 cites W2048286421 @default.
• W3122912182 cites W2049424828 @default.
• W3122912182 cites W2050502424 @default.
• W3122912182 cites W2050808400 @default.
• W3122912182 cites W2052738911 @default.
• W3122912182 cites W2057423581 @default.
• W3122912182 cites W2058133763 @default.
• W3122912182 cites W2059645409 @default.
• W3122912182 cites W2068687308 @default.
• W3122912182 cites W2086601588 @default.
• W3122912182 cites W2086659372 @default.
• W3122912182 cites W2086675887 @default.
• W3122912182 cites W2092221199 @default.
• W3122912182 cites W2094232655 @default.
• W3122912182 cites W2095242498 @default.
• W3122912182 cites W2095782856 @default.
• W3122912182 cites W2099903719 @default.
• W3122912182 cites W2103759705 @default.
• W3122912182 cites W2108544487 @default.
• W3122912182 cites W2109291482 @default.
• W3122912182 cites W2113935262 @default.
• W3122912182 cites W2114814810 @default.
• W3122912182 cites W2117205119 @default.
• W3122912182 cites W2120215319 @default.
• W3122912182 cites W2120840290 @default.
• W3122912182 cites W2125289211 @default.
• W3122912182 cites W2125518431 @default.
• W3122912182 cites W2131668197 @default.
• W3122912182 cites W2152294158 @default.
• W3122912182 cites W2155786005 @default.
• W3122912182 cites W2159438211 @default.
• W3122912182 cites W2160275357 @default.
• W3122912182 cites W2163170761 @default.
• W3122912182 cites W2167673850 @default.
• W3122912182 cites W2168975002 @default.
• W3122912182 cites W2169685512 @default.
• W3122912182 cites W2257096114 @default.
• W3122912182 cites W2271077068 @default.
• W3122912182 cites W2279699986 @default.
• W3122912182 cites W2281100215 @default.
• W3122912182 cites W2321783071 @default.
• W3122912182 cites W2343167842 @default.
• W3122912182 cites W2346077058 @default.
• W3122912182 cites W2346508844 @default.
• W3122912182 cites W2400086340 @default.
• W3122912182 cites W2409292868 @default.
• W3122912182 cites W2409532017 @default.
• W3122912182 cites W2491079799 @default.
• W3122912182 cites W2512126480 @default.
• W3122912182 cites W2546746451 @default.
• W3122912182 cites W2602710454 @default.
• W3122912182 cites W2730369721 @default.
• W3122912182 cites W2766721694 @default.
• W3122912182 cites W2774342205 @default.
• W3122912182 cites W2783873885 @default.
• W3122912182 cites W2800969669 @default.
• W3122912182 cites W2894724600 @default.
• W3122912182 cites W3021993348 @default.

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