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• W3123022905 abstract "<h2>Abstract</h2><h3>Background</h3> Recent publications have increasingly demonstrated a link between superficial-vein thrombosis (SVT) and deep-vein thrombosis (DVT) in the adult population and have led to changes in SVT treatment considerations. A similar relationship between SVT and DVT in pediatric populations, however, is not currently well established. <h3>Objectives</h3> We sought to evaluate the temporal and anatomic relationship between SVT and DVT among pediatric inpatients in order to determine to what degree SVT is associated with DVT. <h3>Methods</h3> We first retrospectively reviewed our institution's local prospective hospital-acquired VTE (HA-VTE) registry to identify all children (age 0–21 years, inclusive) admitted to Children's Hospital Colorado for more than 48 h between January 2012 and September 2017 who developed a DVT while hospitalized. We then reviewed each patient's electronic health record for evidence of SVT to identify SVT + DVT cases. Afterwards, we utilized a list of ICD codes to identify all patients during this time frame who developed an SVT and removed patients whom we previously identified as SVT + DVT cases to obtain the number of patients with isolated SVT. <h3>Results</h3> Of 59,910 patients admitted during the study period, 438 (0.7%) developed a thrombosis while hospitalized - 197 (0.3%) with isolated SVT, 161 (0.3%) with isolated DVT, and 80 (0.1%) with both SVT + DVT. These 80 SVT + DVT patients represent 33% of the 241 total DVT patients and 29% of the 277 total SVT patients. Of the 12 SVT + DVT patients in whom the SVT was diagnosed before the DVT, the subsequent DVT occurred within a mean of 6.4 (range 1–22) days and at the same anatomic site in 6 (50%). The age breakdown for this cohort was: 0 (0%) 0–1 months, 2 (17%) 1 month-2 years, 3 (25%) 2–12 years, 3 (25%) 12–16 years, and 4 (33%) 16–21 years. <h3>Conclusions</h3> Our results indicate a temporal and anatomic relationship between SVT and DVT in hospitalized children, particularly those with central venous catheters." @default.
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• W3123022905 date "2021-04-01" @default.
• W3123022905 modified "2023-09-26" @default.
• W3123022905 title "Temporal and anatomic relationship between superficial and deep vein thromboses in hospitalized children" @default.
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• W3123022905 doi "https://doi.org/10.1016/j.thromres.2021.01.010" @default.
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