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• W3123029086 abstract "Abstract Introduction Children with Down syndrome (DS) who have Laryngomalacia represent a specific management challenge due to their inherent multiple levels of airway obstruction and hypotonia. Therefore, the purpose of this study is to determine the outcome of supraglottoplasty (SGP) in children with DS. Data source A systematic review was performed following the PRISMA guideline. Data were collected from online medical databases– CINAHL, Cochrane Library, Google Scholar, Ovid MEDLINE, Ovid MEDLINE in process, PubMed, and Scopus. Review methods all publications that address the outcome of supraglottoplasty in children who are less than 18 years old with Down syndrome prior to December 2018 were collected. The data were collected on different phases: Screening review using search words and controlled vocabularies during the period of November–December 2018, followed by a detailed review of screened articles based on inclusion and exclusion criteria, then a full review that included screening the references of selected articles. Results Nine articles were included in the qualitative analysis. These articles included 231 subjects, out of which 32 children with DS met the inclusion criteria. Twenty patients (62.5%) were considered successfully treated and 12/32 failed including 1/32 (3.1%) mortality in the postoperative period. The duration of follow-up was 12–102 days. All of the patients whose treatment failed had significant comorbidities. Conclusion Although the success of SPG in children with DS is less than in otherwise healthy children, it remains an option especially in patients without comorbidities. Preoperative counseling of the families and thorough assessment are necessary to determine candidacy for SPG in children with DS." @default.
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• W3123029086 date "2021-03-01" @default.
• W3123029086 modified "2023-10-16" @default.
• W3123029086 title "Supraglottoplasty in the management of laryngomalacia in children with down syndrome: A systematic review" @default.
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• W3123029086 doi "https://doi.org/10.1016/j.ijporl.2021.110630" @default.
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