Matches in SemOpenAlex for { <https://semopenalex.org/work/W3123047185> ?p ?o ?g. }
- W3123047185 endingPage "1130" @default.
- W3123047185 startingPage "1122" @default.
- W3123047185 abstract "Limited data are available regarding the immunogenicity of high-dose influenza vaccine among persons with chronic lymphocytic leukemia (CLL) and monoclonal B cell lymphocytosis (MBL).A prospective pilot study of humoral immune responses to 2013-2014 and 2014-2015 high-dose trivalent influenza vaccine (HD IIV; Fluzone® High-Dose; Sanofi Pasteur) was conducted among individuals with MBL and previously untreated CLL. Serum hemagglutination inhibition (HAI) antibody titers were measured at baseline and Day 28 after vaccination; seroprotection and seroconversion rates were determined. Memory B cell responses were assessed by B-cell enzyme-linked immune absorbent spotassays.Thirty subjects (17 CLL and 13 MBL) were included. Median age was 69.5 years. Day 28 seroprotection rates for the cohort were 19/30 (63.3%) for A/H1N1; 21/23 (91.3%) for A/H3N2; and 13/30 (43.3%) for influenza B. Those with MBL achieved higher day 28 HAI geometric mean titers (54.1 [4.9, 600.1] vs. 12.1 [1.3, 110.1]; p = 0.01) and higher Day 28 seroprotection rates (76.9% vs. 17.6%; p = 0.002) against the influenza B-vaccine strain virus than those with CLL.Immunogenicity of the HD IIV3 in patients with CLL and MBL is lower than reported in healthy adults. Immunogenicity to influenza B was greater in those with MBL than CLL." @default.
- W3123047185 created "2021-02-01" @default.
- W3123047185 creator A5002515721 @default.
- W3123047185 creator A5009747339 @default.
- W3123047185 creator A5019279653 @default.
- W3123047185 creator A5033728545 @default.
- W3123047185 creator A5033825180 @default.
- W3123047185 creator A5045012942 @default.
- W3123047185 creator A5051752737 @default.
- W3123047185 creator A5057546038 @default.
- W3123047185 creator A5075005037 @default.
- W3123047185 creator A5087258737 @default.
- W3123047185 creator A5091799325 @default.
- W3123047185 date "2021-02-01" @default.
- W3123047185 modified "2023-10-10" @default.
- W3123047185 title "The humoral immune response to high-dose influenza vaccine in persons with monoclonal B-cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL)" @default.
- W3123047185 cites W1569582295 @default.
- W3123047185 cites W1603564299 @default.
- W3123047185 cites W179283128 @default.
- W3123047185 cites W1966623111 @default.
- W3123047185 cites W1973128338 @default.
- W3123047185 cites W1975835664 @default.
- W3123047185 cites W1980075357 @default.
- W3123047185 cites W1988580322 @default.
- W3123047185 cites W2002112016 @default.
- W3123047185 cites W2005680325 @default.
- W3123047185 cites W2020995266 @default.
- W3123047185 cites W2024360770 @default.
- W3123047185 cites W2034597154 @default.
- W3123047185 cites W2036586160 @default.
- W3123047185 cites W2038592860 @default.
- W3123047185 cites W2043247840 @default.
- W3123047185 cites W2046560304 @default.
- W3123047185 cites W2049552447 @default.
- W3123047185 cites W2057686471 @default.
- W3123047185 cites W2065435755 @default.
- W3123047185 cites W2085561435 @default.
- W3123047185 cites W2089344948 @default.
- W3123047185 cites W2099127292 @default.
- W3123047185 cites W2105395255 @default.
- W3123047185 cites W2106787323 @default.
- W3123047185 cites W2139400179 @default.
- W3123047185 cites W2150044749 @default.
- W3123047185 cites W2151093863 @default.
- W3123047185 cites W2154553633 @default.
- W3123047185 cites W2155915503 @default.
- W3123047185 cites W2156804837 @default.
- W3123047185 cites W2158313081 @default.
- W3123047185 cites W2168805652 @default.
- W3123047185 cites W2245415865 @default.
- W3123047185 cites W2509761270 @default.
- W3123047185 cites W2512575699 @default.
- W3123047185 cites W253835257 @default.
- W3123047185 cites W2594157024 @default.
- W3123047185 cites W2730462468 @default.
- W3123047185 cites W2735193038 @default.
- W3123047185 cites W2759599398 @default.
- W3123047185 cites W3005578003 @default.
- W3123047185 cites W3011607847 @default.
- W3123047185 cites W4230226206 @default.
- W3123047185 cites W55529990 @default.
- W3123047185 doi "https://doi.org/10.1016/j.vaccine.2021.01.001" @default.
- W3123047185 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8189080" @default.
- W3123047185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33461835" @default.
- W3123047185 hasPublicationYear "2021" @default.
- W3123047185 type Work @default.
- W3123047185 sameAs 3123047185 @default.
- W3123047185 citedByCount "25" @default.
- W3123047185 countsByYear W31230471852021 @default.
- W3123047185 countsByYear W31230471852022 @default.
- W3123047185 countsByYear W31230471852023 @default.
- W3123047185 crossrefType "journal-article" @default.
- W3123047185 hasAuthorship W3123047185A5002515721 @default.
- W3123047185 hasAuthorship W3123047185A5009747339 @default.
- W3123047185 hasAuthorship W3123047185A5019279653 @default.
- W3123047185 hasAuthorship W3123047185A5033728545 @default.
- W3123047185 hasAuthorship W3123047185A5033825180 @default.
- W3123047185 hasAuthorship W3123047185A5045012942 @default.
- W3123047185 hasAuthorship W3123047185A5051752737 @default.
- W3123047185 hasAuthorship W3123047185A5057546038 @default.
- W3123047185 hasAuthorship W3123047185A5075005037 @default.
- W3123047185 hasAuthorship W3123047185A5087258737 @default.
- W3123047185 hasAuthorship W3123047185A5091799325 @default.
- W3123047185 hasBestOaLocation W31230471852 @default.
- W3123047185 hasConcept C159047783 @default.
- W3123047185 hasConcept C159654299 @default.
- W3123047185 hasConcept C203014093 @default.
- W3123047185 hasConcept C22070199 @default.
- W3123047185 hasConcept C2777451964 @default.
- W3123047185 hasConcept C2777938653 @default.
- W3123047185 hasConcept C2778461978 @default.
- W3123047185 hasConcept C2780126324 @default.
- W3123047185 hasConcept C2780689484 @default.
- W3123047185 hasConcept C2780868878 @default.
- W3123047185 hasConcept C71924100 @default.
- W3123047185 hasConcept C8891405 @default.
- W3123047185 hasConceptScore W3123047185C159047783 @default.
- W3123047185 hasConceptScore W3123047185C159654299 @default.