Matches in SemOpenAlex for { <https://semopenalex.org/work/W3123465251> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W3123465251 abstract "Damage to regional cerebrovascular network and neuronal tissues occurs during acute cerebrovascular diseases, such as ischemic stroke. The promotion of vascular regeneration is the most promising therapeutic approach. To understand cellular and molecular mechanisms underlying brain vascular regeneration, we developed two zebrafish cerebrovascular injury models using genetic ablation and photochemical thrombosis. Although brain parenchyma is physiologically devoid of lymphatic vasculature, we found that cerebrovascular injuries induce rapid ingrowth of meningeal lymphatics into the injured parenchyma. The ingrown lymphatics on one hand become lumenized drain interstitial fluid to resolve brain edema, on the other hand act as growing tracks for nascent blood vessels. The ingrown lymphatic vessels undergo apoptosis and clearance after cerebrovascular regeneration. This study reveals a pathological function of meningeal lymphatics, through previously unexpected ingrowth into brain parenchyma and a newly identified lymphatic function as vascular growing tracks." @default.
- W3123465251 created "2021-02-01" @default.
- W3123465251 creator A5001864927 @default.
- W3123465251 creator A5039722157 @default.
- W3123465251 creator A5050451918 @default.
- W3123465251 creator A5061945904 @default.
- W3123465251 creator A5078052506 @default.
- W3123465251 date "2018-01-01" @default.
- W3123465251 modified "2023-09-28" @default.
- W3123465251 title "Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish" @default.
- W3123465251 doi "https://doi.org/10.2139/ssrn.3239667" @default.
- W3123465251 hasPublicationYear "2018" @default.
- W3123465251 type Work @default.
- W3123465251 sameAs 3123465251 @default.
- W3123465251 citedByCount "0" @default.
- W3123465251 crossrefType "journal-article" @default.
- W3123465251 hasAuthorship W3123465251A5001864927 @default.
- W3123465251 hasAuthorship W3123465251A5039722157 @default.
- W3123465251 hasAuthorship W3123465251A5050451918 @default.
- W3123465251 hasAuthorship W3123465251A5061945904 @default.
- W3123465251 hasAuthorship W3123465251A5078052506 @default.
- W3123465251 hasBestOaLocation W31234652512 @default.
- W3123465251 hasConcept C104317684 @default.
- W3123465251 hasConcept C105702510 @default.
- W3123465251 hasConcept C141071460 @default.
- W3123465251 hasConcept C142724271 @default.
- W3123465251 hasConcept C171056886 @default.
- W3123465251 hasConcept C181152851 @default.
- W3123465251 hasConcept C196822366 @default.
- W3123465251 hasConcept C2776878037 @default.
- W3123465251 hasConcept C2779822359 @default.
- W3123465251 hasConcept C2780868729 @default.
- W3123465251 hasConcept C2780886150 @default.
- W3123465251 hasConcept C55493867 @default.
- W3123465251 hasConcept C71924100 @default.
- W3123465251 hasConcept C86803240 @default.
- W3123465251 hasConcept C95444343 @default.
- W3123465251 hasConceptScore W3123465251C104317684 @default.
- W3123465251 hasConceptScore W3123465251C105702510 @default.
- W3123465251 hasConceptScore W3123465251C141071460 @default.
- W3123465251 hasConceptScore W3123465251C142724271 @default.
- W3123465251 hasConceptScore W3123465251C171056886 @default.
- W3123465251 hasConceptScore W3123465251C181152851 @default.
- W3123465251 hasConceptScore W3123465251C196822366 @default.
- W3123465251 hasConceptScore W3123465251C2776878037 @default.
- W3123465251 hasConceptScore W3123465251C2779822359 @default.
- W3123465251 hasConceptScore W3123465251C2780868729 @default.
- W3123465251 hasConceptScore W3123465251C2780886150 @default.
- W3123465251 hasConceptScore W3123465251C55493867 @default.
- W3123465251 hasConceptScore W3123465251C71924100 @default.
- W3123465251 hasConceptScore W3123465251C86803240 @default.
- W3123465251 hasConceptScore W3123465251C95444343 @default.
- W3123465251 hasLocation W31234652511 @default.
- W3123465251 hasLocation W31234652512 @default.
- W3123465251 hasOpenAccess W3123465251 @default.
- W3123465251 hasPrimaryLocation W31234652511 @default.
- W3123465251 hasRelatedWork W156718405 @default.
- W3123465251 hasRelatedWork W1746934092 @default.
- W3123465251 hasRelatedWork W2120614448 @default.
- W3123465251 hasRelatedWork W2131398028 @default.
- W3123465251 hasRelatedWork W2154262476 @default.
- W3123465251 hasRelatedWork W2162598382 @default.
- W3123465251 hasRelatedWork W2298163613 @default.
- W3123465251 hasRelatedWork W2491469714 @default.
- W3123465251 hasRelatedWork W2747441624 @default.
- W3123465251 hasRelatedWork W2808431855 @default.
- W3123465251 hasRelatedWork W2883628966 @default.
- W3123465251 hasRelatedWork W2883916734 @default.
- W3123465251 hasRelatedWork W2899187097 @default.
- W3123465251 hasRelatedWork W2914645061 @default.
- W3123465251 hasRelatedWork W2948169674 @default.
- W3123465251 hasRelatedWork W2950471695 @default.
- W3123465251 hasRelatedWork W2970656496 @default.
- W3123465251 hasRelatedWork W3044089250 @default.
- W3123465251 hasRelatedWork W72867930 @default.
- W3123465251 isParatext "false" @default.
- W3123465251 isRetracted "false" @default.
- W3123465251 magId "3123465251" @default.
- W3123465251 workType "article" @default.