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• W3123494408 abstract "More than a century after Richard Semon's theoretical proposal of the memory engram, technological advancements have finally enabled experimental access to engram cells and their functional contents. In this review, we summarize theories and their experimental support regarding hippocampal memory engram formation and function. Specifically, we discuss recent advances in the engram field which help to reconcile two main theories for how the hippocampus supports memory formation: The Memory Indexing and Cognitive Map theories. We also highlight the latest evidence for engram allocation mechanisms through which memories can be linked or separately encoded. Finally, we identify unanswered questions for future investigations, through which a more comprehensive understanding of memory formation and retrieval may be achieved." @default.
• W3123494408 created "2021-02-01" @default.
• W3123494408 creator A5019571024 @default.
• W3123494408 creator A5037917072 @default.
• W3123494408 creator A5068252474 @default.
• W3123494408 date "2021-01-15" @default.
• W3123494408 modified "2023-10-17" @default.
• W3123494408 title "The Quest for the Hippocampal Memory Engram: From Theories to Experimental Evidence" @default.
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