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• W3124064516 abstract "B lymphocytes produce antibodies under the stimulation of specific antigens, thereby exerting an immune effect. B cells identify antigens by their surface B cell receptor (BCR), which upon stimulation, directs the cell to activate and differentiate into antibody generating plasma cells. Activation of B cells via their BCRs involves signaling pathways that are tightly controlled by various regulators. In this review, we will discuss three major BCR mediated signaling pathways (the PLC-γ2 pathway, PI3K pathway and MAPK pathway) and related regulators, which were roughly divided into positive, negative and mutual-balanced regulators, and the specific regulators of the specific signaling pathway based on regulatory effects." @default.
• W3124064516 created "2021-02-01" @default.
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• W3124064516 creator A5088310329 @default.
• W3124064516 date "2019-10-01" @default.
• W3124064516 modified "2023-10-14" @default.
• W3124064516 title "The regulators of BCR signaling during B cell activation" @default.
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