Matches in SemOpenAlex for { <https://semopenalex.org/work/W3124202938> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W3124202938 abstract "Background Objectives To compare efficiency and safety of 4-week treatment by nimesulid, diclophenac and diclophenac in a combination with lansoprazole in osteoarthritis patients. Methods We observed 167 patients (130 women and 37 men, mean age 54 years). During 4 weeks in the first group 74 patients received diclophenac 100 mg per day, in the second group 31 patients – diclophenac in a combination with lansoprazole 30 mg per day and in the third group 62 patients received nimesulid 200 mg per day. Before and after 4-weeks treatment were estimated of a clinical symptomatology, upper GI endoscopy, 24 h Oi-metry (Digitrapper MkIII, Synectics, Sweden), histological research of biopsy of a mucosa from antral part of a stomach. For a estimate of clinical effi-ciency was used a questionnaire of a quality of life SF-36. Results The clinical efficiency of therapy by diclophenac or nimesulid in osteoarthritis patients was comparable. The frequency of development of erosions and ulcers of a stomach was higher at diclophenac group (41%), than at nimesulid group (24%). The combination of diclophenac and lansoprazole has allowed to lower frequency of development of erosions and ulcers of a stomach mucosa to 16%. Positive dynamics of morpho-functional of parameters of a stomach mucosa in lansoprazole group was found. Conclusion Our results prove gastroprotective effect of lansoprazole. The application lansoprazole for osteoarthritis patients long-time receiving diclophenac is accompanied by positive dynamics morphofunctional parameters of a mucosa of a stomach, lowering of frequency of development of erosions and ulcers of a stomach." @default.
- W3124202938 created "2021-02-01" @default.
- W3124202938 creator A5052001967 @default.
- W3124202938 creator A5078667596 @default.
- W3124202938 creator A5079891886 @default.
- W3124202938 date "2001-06-01" @default.
- W3124202938 modified "2023-09-23" @default.
- W3124202938 title "AB0143 Gastroprotective effect of lansoprazole in osteoarthritis pa-tients long-time receiving diclophenac" @default.
- W3124202938 doi "https://doi.org/10.1136/annrheumdis-2001.405" @default.
- W3124202938 hasPublicationYear "2001" @default.
- W3124202938 type Work @default.
- W3124202938 sameAs 3124202938 @default.
- W3124202938 citedByCount "0" @default.
- W3124202938 crossrefType "proceedings-article" @default.
- W3124202938 hasAuthorship W3124202938A5052001967 @default.
- W3124202938 hasAuthorship W3124202938A5078667596 @default.
- W3124202938 hasAuthorship W3124202938A5079891886 @default.
- W3124202938 hasBestOaLocation W31242029381 @default.
- W3124202938 hasConcept C126322002 @default.
- W3124202938 hasConcept C131253125 @default.
- W3124202938 hasConcept C142724271 @default.
- W3124202938 hasConcept C204787440 @default.
- W3124202938 hasConcept C2776164576 @default.
- W3124202938 hasConcept C2776409635 @default.
- W3124202938 hasConcept C2778715759 @default.
- W3124202938 hasConcept C2779422922 @default.
- W3124202938 hasConcept C2781443798 @default.
- W3124202938 hasConcept C71924100 @default.
- W3124202938 hasConcept C90924648 @default.
- W3124202938 hasConceptScore W3124202938C126322002 @default.
- W3124202938 hasConceptScore W3124202938C131253125 @default.
- W3124202938 hasConceptScore W3124202938C142724271 @default.
- W3124202938 hasConceptScore W3124202938C204787440 @default.
- W3124202938 hasConceptScore W3124202938C2776164576 @default.
- W3124202938 hasConceptScore W3124202938C2776409635 @default.
- W3124202938 hasConceptScore W3124202938C2778715759 @default.
- W3124202938 hasConceptScore W3124202938C2779422922 @default.
- W3124202938 hasConceptScore W3124202938C2781443798 @default.
- W3124202938 hasConceptScore W3124202938C71924100 @default.
- W3124202938 hasConceptScore W3124202938C90924648 @default.
- W3124202938 hasLocation W31242029381 @default.
- W3124202938 hasOpenAccess W3124202938 @default.
- W3124202938 hasPrimaryLocation W31242029381 @default.
- W3124202938 hasRelatedWork W1516694597 @default.
- W3124202938 hasRelatedWork W178710661 @default.
- W3124202938 hasRelatedWork W1805648369 @default.
- W3124202938 hasRelatedWork W1963960033 @default.
- W3124202938 hasRelatedWork W1964302600 @default.
- W3124202938 hasRelatedWork W1981499783 @default.
- W3124202938 hasRelatedWork W2070501998 @default.
- W3124202938 hasRelatedWork W2328892908 @default.
- W3124202938 hasRelatedWork W2366197822 @default.
- W3124202938 hasRelatedWork W2366826019 @default.
- W3124202938 hasRelatedWork W2369024320 @default.
- W3124202938 hasRelatedWork W2370234364 @default.
- W3124202938 hasRelatedWork W2378318047 @default.
- W3124202938 hasRelatedWork W2389642931 @default.
- W3124202938 hasRelatedWork W2393078415 @default.
- W3124202938 hasRelatedWork W2393480142 @default.
- W3124202938 hasRelatedWork W2407201152 @default.
- W3124202938 hasRelatedWork W2440633103 @default.
- W3124202938 hasRelatedWork W3148976270 @default.
- W3124202938 hasRelatedWork W3190274774 @default.
- W3124202938 isParatext "false" @default.
- W3124202938 isRetracted "false" @default.
- W3124202938 magId "3124202938" @default.
- W3124202938 workType "article" @default.