FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3124210149> ?p ?o ?g. }

• W3124210149 endingPage "32" @default.
• W3124210149 startingPage "26" @default.
• W3124210149 abstract "To explore the influence factors of anterior bone loss (ABL) after cervical disc arthroplasty (CDA) and effects of ABL on the clinical and radiographic outcomes.One hundred and fifty-five patients who underwent single-level Prestige-LP CDA between January 2008 and December 2017 and met the inclusive criteria were enrolled in the study. Perioperative data of patients were collected. The Japanese Orthopaedic Association (JOA) score, Neck Disability Index (NDI), and the visual analogue scale (VAS) score were used for clinical outcomes evaluation. Radiographic parameters including cervical lordosis, C 2-7 range of motion (ROM), disc angle, segmental ROM, and the lengths of the upper and lower endplates were assessed on the X-ray films. Device-related complications, including ABL, subsidence, radiographic adjacent segment pathology, and heterotopic ossification, were recorded. Univariate analysis was used to analyze the related factors, and logistic regression analysis was used to screen the influence factors. Patients were grouped according to whether ABL occurred after operation, and the differences in clinical and imaging evaluation parameters were compared.There were 94 cases (60.6%) in the ABL group and 61 cases (39.4%) in the non-ABL group. Univariate analysis showed the significant differences in age, body mass index (BMI), and intraoperative blood loss between the two groups ( P<0.05). However, there was no significant difference in gender, bone mineral density (T value), preoperative blood calcium level, preoperative blood phosphorus level, preoperative alkaline phosphatase level, operative segment, operative time, and follow-up time between the two groups ( P>0.05). Multivariate analysis showed that the age and BMI were influence factors for ABL after CDA ( P<0.05). The JOA score, NDI, and VAS score significantly improved in both groups at 3 months after operation ( P<0.05), and the scores were further improved at last follow-up ( P<0.05). There was no significant difference in JOA score, NDI, and VAS score between the two groups before and after operation ( P>0.05). The preoperative cervical lordosis was significantly smaller in the ABL group than in the non-ABL group ( t=-2.402, P=0.018). At last follow-up, the segmental ROM was significantly greater in the ABL group than in the non-ABL group ( P<0.05), and the lengths of the upper and lower endplates were less in the ABL group than in the non-ABL group ( P<0.05). No significant difference in the other radiographic parameters between the two groups were found ( P>0.05). Prosthesis subsidence occurred in 5 cases (3.2%), including 3 cases in the ABL group and 2 cases in the non-ABL group; the difference between the two groups was not significant ( P=1.000). Heterotopic ossification occurred in 67 cases (43.2%), including 32 cases in the ABL group and 35 cases in the non-ABL group; the difference between the two groups was significant ( χ2=8.208, P=0.004). High-grade heterotopic ossification was detected in 26 cases (13 cases in the ABL group and 13 cases in the non-ABL group). Twenty-nine cases (18.7%) had radiographic adjacent segment pathology, including 15 cases in the ABL group and 14 cases in non-ABL group; the difference between the two groups was not significant ( χ2=1.190, P=0.276).The incidence of ABL after CDA was relatively high, which mainly occurred within 3 months after operation, and no longer progressing with stable radiographic features after the first 12 months. Age and BMI were independent influence factors for ABL. ABL does not affect the clinical outcomes but may preserve more ROM of prostheses.探讨人工颈椎间盘置换术（cervical disc arthroplasty，CDA）后发生椎体前缘骨吸收（anterior bone loss，ABL）的影响因素以及 ABL 对 CDA 疗效的影响。.以 2008 年 1 月—2017 年 12 月接受单节段 Prestige-LP 人工颈椎间盘 CDA 治疗且符合选择标准的 155 例患者作为研究对象。收集患者围术期资料，临床疗效评价指标包括日本骨科协会（JOA）评分、颈椎功能障碍指数（NDI）以及疼痛视觉模拟评分（VAS）；影像学评价指标包括颈椎曲度、C 2～7 活动度（range of motion，ROM）、椎间角度、节段 ROM 以及上、下终板长度；记录假体相关并发症发生情况，包括 ABL、假体下沉、邻近节段影像学退变以及异位骨化。采用单因素分析 ABL 相关影响因素，进一步以 logistic 回归分析筛选 ABL 独立影响因素。将患者按照术后是否发生 ABL 进行分组，比较临床及影像学评价指标差异。.155 例患者中，术后发生 ABL 94 例（60.6%，ABL 组）、未发生 ABL 61 例（39.4%，无 ABL 组）。单因素分析显示，两组患者年龄、体质量指数（body mass index，BMI）、术中出血量比较差异有统计学意义（ P<0.05），性别、骨密度（T 值）、术前血钙、术前血磷、术前 ALP、手术节段、手术时间及随访时间比较，差异均无统计学意义（ P>0.05）。多因素分析显示年龄和 BMI 是 CDA 术后发生 ABL 的影响因素（ P<0.05）。临床疗效评价显示，两组术后 JOA 评分、NDI、VAS 评分均较术前明显改善，末次随访时较术后 3 个月进一步改善，差异有统计学意义（ P<0.05）。两组术前及术后 3 个月、末次随访时 JOA 评分、NDI、VAS 评分比较，差异均无统计学意义（ P>0.05）。影像学评价显示，术前无 ABL 组颈椎曲度明显大于 ABL 组（ t=−2.402， P=0.018）；末次随访时 ABL 组节段 ROM 大于无 ABL 组，上、下终板长度小于无 ABL 组，差异均有统计学意义（ P<0.05）；其余各时间点影像学指标比较差异均无统计学意义（ P>0.05）。随访期间 5 例（3.2%）发生假体下沉，ABL 组 3 例、无 ABL 组 2 例，差异无统计学意义（ P=1.000）。67 例（43.2%）发生异位骨化，ABL 组 32 例、无 ABL 组 35 例，差异有统计学意义（ χ2=8.208， P=0.004）；其中，高等级异位骨化 26 例（ABL 组 13 例、无 ABL 组 13 例）。29 例（18.7%）发生邻近节段影像学退变，ABL 组 15 例、无 ABL 组 14 例，差异无统计学意义（ χ2=1.190， P=0.276）。.CDA 术后 ABL 发生率较高，主要发生在术后 3 个月内，术后 12 个月内达稳定且不再进展，年龄和 BMI 是 ABL 发生的独立影响因素。ABL 对临床疗效无明显影响，可能对手术节段假体活动功能的保留有积极作用。." @default.
• W3124210149 created "2021-02-01" @default.
• W3124210149 creator A5007257498 @default.
• W3124210149 creator A5008636823 @default.
• W3124210149 creator A5014869234 @default.
• W3124210149 creator A5022985898 @default.
• W3124210149 creator A5027071448 @default.
• W3124210149 creator A5032751866 @default.
• W3124210149 creator A5038798689 @default.
• W3124210149 creator A5050755783 @default.
• W3124210149 creator A5067750942 @default.
• W3124210149 creator A5082413907 @default.
• W3124210149 creator A5086216176 @default.
• W3124210149 date "2021-01-15" @default.
• W3124210149 modified "2023-10-18" @default.
• W3124210149 title "[Analysis of infuence factors of anterior bone loss after cervical disc arthroplasty and its effect on effectiveness]." @default.
• W3124210149 cites W1979367920 @default.
• W3124210149 cites W2012950568 @default.
• W3124210149 cites W2032435618 @default.
• W3124210149 cites W2043226009 @default.
• W3124210149 cites W2052854874 @default.
• W3124210149 cites W2066694927 @default.
• W3124210149 cites W2103360140 @default.
• W3124210149 cites W2127585686 @default.
• W3124210149 cites W2128690996 @default.
• W3124210149 cites W2157981582 @default.
• W3124210149 cites W2253909102 @default.
• W3124210149 cites W2563488620 @default.
• W3124210149 cites W2584705177 @default.
• W3124210149 cites W2890591177 @default.
• W3124210149 cites W2896250657 @default.
• W3124210149 cites W2931486674 @default.
• W3124210149 cites W2944759241 @default.
• W3124210149 cites W3021986819 @default.
• W3124210149 cites W3034567556 @default.
• W3124210149 doi "https://doi.org/10.7507/1002-1892.202008126" @default.
• W3124210149 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8171609" @default.
• W3124210149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33448195" @default.
• W3124210149 hasPublicationYear "2021" @default.
• W3124210149 type Work @default.
• W3124210149 sameAs 3124210149 @default.
• W3124210149 citedByCount "0" @default.
• W3124210149 crossrefType "journal-article" @default.
• W3124210149 hasAuthorship W3124210149A5007257498 @default.
• W3124210149 hasAuthorship W3124210149A5008636823 @default.
• W3124210149 hasAuthorship W3124210149A5014869234 @default.
• W3124210149 hasAuthorship W3124210149A5022985898 @default.
• W3124210149 hasAuthorship W3124210149A5027071448 @default.
• W3124210149 hasAuthorship W3124210149A5032751866 @default.
• W3124210149 hasAuthorship W3124210149A5038798689 @default.
• W3124210149 hasAuthorship W3124210149A5050755783 @default.
• W3124210149 hasAuthorship W3124210149A5067750942 @default.
• W3124210149 hasAuthorship W3124210149A5082413907 @default.
• W3124210149 hasAuthorship W3124210149A5086216176 @default.
• W3124210149 hasConcept C126322002 @default.
• W3124210149 hasConcept C141071460 @default.
• W3124210149 hasConcept C14184104 @default.
• W3124210149 hasConcept C144301174 @default.
• W3124210149 hasConcept C2780221984 @default.
• W3124210149 hasConcept C2780650075 @default.
• W3124210149 hasConcept C31174226 @default.
• W3124210149 hasConcept C36454342 @default.
• W3124210149 hasConcept C38180746 @default.
• W3124210149 hasConcept C60465272 @default.
• W3124210149 hasConcept C71924100 @default.
• W3124210149 hasConceptScore W3124210149C126322002 @default.
• W3124210149 hasConceptScore W3124210149C141071460 @default.
• W3124210149 hasConceptScore W3124210149C14184104 @default.
• W3124210149 hasConceptScore W3124210149C144301174 @default.
• W3124210149 hasConceptScore W3124210149C2780221984 @default.
• W3124210149 hasConceptScore W3124210149C2780650075 @default.
• W3124210149 hasConceptScore W3124210149C31174226 @default.
• W3124210149 hasConceptScore W3124210149C36454342 @default.
• W3124210149 hasConceptScore W3124210149C38180746 @default.
• W3124210149 hasConceptScore W3124210149C60465272 @default.
• W3124210149 hasConceptScore W3124210149C71924100 @default.
• W3124210149 hasIssue "1" @default.
• W3124210149 hasLocation W31242101491 @default.
• W3124210149 hasOpenAccess W3124210149 @default.
• W3124210149 hasPrimaryLocation W31242101491 @default.
• W3124210149 hasRelatedWork W10669233 @default.
• W3124210149 hasRelatedWork W11818958 @default.
• W3124210149 hasRelatedWork W15462673 @default.
• W3124210149 hasRelatedWork W15991227 @default.
• W3124210149 hasRelatedWork W18679344 @default.
• W3124210149 hasRelatedWork W19940195 @default.
• W3124210149 hasRelatedWork W21250264 @default.
• W3124210149 hasRelatedWork W373436 @default.
• W3124210149 hasRelatedWork W5184025 @default.
• W3124210149 hasRelatedWork W5270506 @default.
• W3124210149 hasVolume "35" @default.
• W3124210149 isParatext "false" @default.
• W3124210149 isRetracted "false" @default.
• W3124210149 magId "3124210149" @default.
• W3124210149 workType "article" @default.