Matches in SemOpenAlex for { <https://semopenalex.org/work/W3124584989> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3124584989 abstract "In this study, we tried to estimate the economic potential benefit of the use of fluoxetine (PROZACR 20 mg, Lilly) versus tricyclic antidepressants (TCAs) in depression of mild to moderate intensity. Fluoxetine has demonstrated, in controlled studies, significantly lower rates of side-effects and treatment dropout than TCAs while showing similar efficacy. Treatment dropout, especially at an early stage of the therapy, can have profound consequences, including excessive lengthening of the depressive episode, symptomatic relapse, increase of repeated days out of work, even suicides or suicide attempts. We estimated the expected cost of treatment dropout using a Delphi expert panel. We then computed the economic benefit of fluoxetine by combining the dropout cost and the differential rate of total treatment dropout between fluoxetine and TCAs, as found in clinical trials. We thus showed that a 8 week fluoxetine could be beneficial to society provided society values a year of human life above a threshold varying from French Francs 23.800 to FF8.600 (respectively, about US$4500 and 1600) depending on the type of depression. As these values are extremely low compared to those found in the literature, we concluded that an apparently costly innovation such as fluoxetine may induce short-term financial savings for society." @default.
- W3124584989 created "2021-02-01" @default.
- W3124584989 creator A5033082386 @default.
- W3124584989 creator A5035961186 @default.
- W3124584989 creator A5041169452 @default.
- W3124584989 creator A5068512939 @default.
- W3124584989 creator A5084187605 @default.
- W3124584989 date "1994-01-01" @default.
- W3124584989 modified "2023-09-26" @default.
- W3124584989 title "The cost of treatment dropout in depression A cost-benefit analysis of fluoxetine vs. tricyclics" @default.
- W3124584989 hasPublicationYear "1994" @default.
- W3124584989 type Work @default.
- W3124584989 sameAs 3124584989 @default.
- W3124584989 citedByCount "0" @default.
- W3124584989 crossrefType "posted-content" @default.
- W3124584989 hasAuthorship W3124584989A5033082386 @default.
- W3124584989 hasAuthorship W3124584989A5035961186 @default.
- W3124584989 hasAuthorship W3124584989A5041169452 @default.
- W3124584989 hasAuthorship W3124584989A5068512939 @default.
- W3124584989 hasAuthorship W3124584989A5084187605 @default.
- W3124584989 hasConcept C118552586 @default.
- W3124584989 hasConcept C119857082 @default.
- W3124584989 hasConcept C126322002 @default.
- W3124584989 hasConcept C15744967 @default.
- W3124584989 hasConcept C162324750 @default.
- W3124584989 hasConcept C165556158 @default.
- W3124584989 hasConcept C170493617 @default.
- W3124584989 hasConcept C2775864247 @default.
- W3124584989 hasConcept C2776134451 @default.
- W3124584989 hasConcept C2776145597 @default.
- W3124584989 hasConcept C2776867660 @default.
- W3124584989 hasConcept C2781081902 @default.
- W3124584989 hasConcept C41008148 @default.
- W3124584989 hasConcept C71924100 @default.
- W3124584989 hasConcept C98274493 @default.
- W3124584989 hasConceptScore W3124584989C118552586 @default.
- W3124584989 hasConceptScore W3124584989C119857082 @default.
- W3124584989 hasConceptScore W3124584989C126322002 @default.
- W3124584989 hasConceptScore W3124584989C15744967 @default.
- W3124584989 hasConceptScore W3124584989C162324750 @default.
- W3124584989 hasConceptScore W3124584989C165556158 @default.
- W3124584989 hasConceptScore W3124584989C170493617 @default.
- W3124584989 hasConceptScore W3124584989C2775864247 @default.
- W3124584989 hasConceptScore W3124584989C2776134451 @default.
- W3124584989 hasConceptScore W3124584989C2776145597 @default.
- W3124584989 hasConceptScore W3124584989C2776867660 @default.
- W3124584989 hasConceptScore W3124584989C2781081902 @default.
- W3124584989 hasConceptScore W3124584989C41008148 @default.
- W3124584989 hasConceptScore W3124584989C71924100 @default.
- W3124584989 hasConceptScore W3124584989C98274493 @default.
- W3124584989 hasLocation W31245849891 @default.
- W3124584989 hasOpenAccess W3124584989 @default.
- W3124584989 hasPrimaryLocation W31245849891 @default.
- W3124584989 hasRelatedWork W1968782091 @default.
- W3124584989 hasRelatedWork W1970280822 @default.
- W3124584989 hasRelatedWork W1983669226 @default.
- W3124584989 hasRelatedWork W1983700460 @default.
- W3124584989 hasRelatedWork W2032091897 @default.
- W3124584989 hasRelatedWork W2067711950 @default.
- W3124584989 hasRelatedWork W2108993005 @default.
- W3124584989 hasRelatedWork W2140788810 @default.
- W3124584989 hasRelatedWork W2146307286 @default.
- W3124584989 hasRelatedWork W2166580424 @default.
- W3124584989 hasRelatedWork W2339027782 @default.
- W3124584989 hasRelatedWork W2346968617 @default.
- W3124584989 hasRelatedWork W2400143336 @default.
- W3124584989 hasRelatedWork W2510749442 @default.
- W3124584989 hasRelatedWork W2606466050 @default.
- W3124584989 hasRelatedWork W2795882974 @default.
- W3124584989 hasRelatedWork W2924582339 @default.
- W3124584989 hasRelatedWork W2993391635 @default.
- W3124584989 hasRelatedWork W3163280979 @default.
- W3124584989 hasRelatedWork W3205507803 @default.
- W3124584989 isParatext "false" @default.
- W3124584989 isRetracted "false" @default.
- W3124584989 magId "3124584989" @default.
- W3124584989 workType "article" @default.