FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3124756847> ?p ?o ?g. }

• W3124756847 abstract "Background Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives This study examined the effects of bee venom (BV) stimulation on scalding burn injury-induced nociception in mice as a new treatment for burn pain. Methods To develop a burn injury model, the right hind paw was immersed temporarily in hot water (65°C, 3 seconds). Immediately after the burn, BV (0.01, 0.02, or 0.1 mg/kg) was injected subcutaneously into the ipsilateral knee area once daily for 14 days. A von Frey test was performed to assess the nociceptive response, and the altered walking parameters were evaluated using an automated gait analysis system. In addition, the peripheral and central expression changes in substance P (Sub P) were measured in the dorsal root ganglion and spinal cord by immunofluorescence. Results Repeated BV treatment at the 2 higher doses used in this study (0.02 and 0.1 mg/kg) alleviated the pain responses remarkably and recovered the gait performances to the level of acetaminophen (200 mg/kg, intraperitoneal, once daily), which used as the positive control group. Moreover, BV stimulation had an inhibitory effect on the increased expression of Sub P in the peripheral and central nervous systems by a burn injury. Conclusions These results suggest that a peripheral BV treatment may have positive potency in treating burn-induced pain." @default.
• W3124756847 created "2021-02-01" @default.
• W3124756847 creator A5008383067 @default.
• W3124756847 creator A5013172635 @default.
• W3124756847 creator A5034565068 @default.
• W3124756847 creator A5037051977 @default.
• W3124756847 creator A5038375061 @default.
• W3124756847 creator A5048660041 @default.
• W3124756847 date "2021-01-01" @default.
• W3124756847 modified "2023-09-23" @default.
• W3124756847 title "Bee venom reduces burn-induced pain via the suppression of peripheral and central substance P expression in mice" @default.
• W3124756847 cites W1506423973 @default.
• W3124756847 cites W1584689658 @default.
• W3124756847 cites W1587886687 @default.
• W3124756847 cites W1650183152 @default.
• W3124756847 cites W1652577435 @default.
• W3124756847 cites W1989745698 @default.
• W3124756847 cites W2020581752 @default.
• W3124756847 cites W2038686083 @default.
• W3124756847 cites W2045462753 @default.
• W3124756847 cites W2072264089 @default.
• W3124756847 cites W2080386965 @default.
• W3124756847 cites W2090998770 @default.
• W3124756847 cites W2091337398 @default.
• W3124756847 cites W2092208076 @default.
• W3124756847 cites W2101457198 @default.
• W3124756847 cites W2123080797 @default.
• W3124756847 cites W2125186579 @default.
• W3124756847 cites W2154069662 @default.
• W3124756847 cites W2279130728 @default.
• W3124756847 cites W2315819085 @default.
• W3124756847 cites W2508876487 @default.
• W3124756847 cites W2766138609 @default.
• W3124756847 cites W2792799451 @default.
• W3124756847 cites W2940465260 @default.
• W3124756847 cites W2970482736 @default.
• W3124756847 cites W3012531502 @default.
• W3124756847 doi "https://doi.org/10.4142/jvs.2021.22.e9" @default.
• W3124756847 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7850793" @default.
• W3124756847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33522161" @default.
• W3124756847 hasPublicationYear "2021" @default.
• W3124756847 type Work @default.
• W3124756847 sameAs 3124756847 @default.
• W3124756847 citedByCount "2" @default.
• W3124756847 countsByYear W31247568472022 @default.
• W3124756847 countsByYear W31247568472023 @default.
• W3124756847 crossrefType "journal-article" @default.
• W3124756847 hasAuthorship W3124756847A5008383067 @default.
• W3124756847 hasAuthorship W3124756847A5013172635 @default.
• W3124756847 hasAuthorship W3124756847A5034565068 @default.
• W3124756847 hasAuthorship W3124756847A5037051977 @default.
• W3124756847 hasAuthorship W3124756847A5038375061 @default.
• W3124756847 hasAuthorship W3124756847A5048660041 @default.
• W3124756847 hasBestOaLocation W31247568471 @default.
• W3124756847 hasConcept C118303440 @default.
• W3124756847 hasConcept C126322002 @default.
• W3124756847 hasConcept C127413603 @default.
• W3124756847 hasConcept C146978453 @default.
• W3124756847 hasConcept C170493617 @default.
• W3124756847 hasConcept C2776533618 @default.
• W3124756847 hasConcept C2779300339 @default.
• W3124756847 hasConcept C2779448229 @default.
• W3124756847 hasConcept C3020806191 @default.
• W3124756847 hasConcept C42219234 @default.
• W3124756847 hasConcept C46762472 @default.
• W3124756847 hasConcept C55493867 @default.
• W3124756847 hasConcept C71924100 @default.
• W3124756847 hasConcept C86803240 @default.
• W3124756847 hasConcept C90856448 @default.
• W3124756847 hasConcept C98274493 @default.
• W3124756847 hasConceptScore W3124756847C118303440 @default.
• W3124756847 hasConceptScore W3124756847C126322002 @default.
• W3124756847 hasConceptScore W3124756847C127413603 @default.
• W3124756847 hasConceptScore W3124756847C146978453 @default.
• W3124756847 hasConceptScore W3124756847C170493617 @default.
• W3124756847 hasConceptScore W3124756847C2776533618 @default.
• W3124756847 hasConceptScore W3124756847C2779300339 @default.
• W3124756847 hasConceptScore W3124756847C2779448229 @default.
• W3124756847 hasConceptScore W3124756847C3020806191 @default.
• W3124756847 hasConceptScore W3124756847C42219234 @default.
• W3124756847 hasConceptScore W3124756847C46762472 @default.
• W3124756847 hasConceptScore W3124756847C55493867 @default.
• W3124756847 hasConceptScore W3124756847C71924100 @default.
• W3124756847 hasConceptScore W3124756847C86803240 @default.
• W3124756847 hasConceptScore W3124756847C90856448 @default.
• W3124756847 hasConceptScore W3124756847C98274493 @default.
• W3124756847 hasFunder F4320321204 @default.
• W3124756847 hasFunder F4320322120 @default.
• W3124756847 hasIssue "1" @default.
• W3124756847 hasLocation W31247568471 @default.
• W3124756847 hasLocation W31247568472 @default.
• W3124756847 hasLocation W31247568473 @default.
• W3124756847 hasOpenAccess W3124756847 @default.
• W3124756847 hasPrimaryLocation W31247568471 @default.
• W3124756847 hasRelatedWork W1984287565 @default.
• W3124756847 hasRelatedWork W2023171805 @default.
• W3124756847 hasRelatedWork W2090039867 @default.
• W3124756847 hasRelatedWork W2184060541 @default.
• W3124756847 hasRelatedWork W2226231654 @default.
• W3124756847 hasRelatedWork W2370388957 @default.

• next