Matches in SemOpenAlex for { <https://semopenalex.org/work/W3124832125> ?p ?o ?g. }
- W3124832125 endingPage "20.2020" @default.
- W3124832125 startingPage "ENEURO.0231" @default.
- W3124832125 abstract "Intracortical brain-computer interfaces (iBCIs) have the potential to restore hand grasping and object interaction to individuals with tetraplegia. Optimal grasping and object interaction require simultaneous production of both force and grasp outputs. However, since overlapping neural populations are modulated by both parameters, grasp type could affect how well forces are decoded from motor cortex in a closed-loop force iBCI. Therefore, this work quantified the neural representation and offline decoding performance of discrete hand grasps and force levels in two human participants with tetraplegia. Participants attempted to produce three discrete forces (light, medium, hard) using up to five hand grasp configurations. A two-way Welch ANOVA was implemented on multiunit neural features to assess their modulation to force and grasp Demixed principal component analysis (dPCA) was used to assess for population-level tuning to force and grasp and to predict these parameters from neural activity. Three major findings emerged from this work: (1) force information was neurally represented and could be decoded across multiple hand grasps (and, in one participant, across attempted elbow extension as well); (2) grasp type affected force representation within multiunit neural features and offline force classification accuracy; and (3) grasp was classified more accurately and had greater population-level representation than force. These findings suggest that force and grasp have both independent and interacting representations within cortex, and that incorporating force control into real-time iBCI systems is feasible across multiple hand grasps if the decoder also accounts for grasp type." @default.
- W3124832125 created "2021-02-01" @default.
- W3124832125 creator A5004430663 @default.
- W3124832125 creator A5007184945 @default.
- W3124832125 creator A5009856256 @default.
- W3124832125 creator A5017527968 @default.
- W3124832125 creator A5021306973 @default.
- W3124832125 creator A5027111764 @default.
- W3124832125 creator A5029850297 @default.
- W3124832125 creator A5032110460 @default.
- W3124832125 creator A5037890134 @default.
- W3124832125 creator A5043635179 @default.
- W3124832125 creator A5044559619 @default.
- W3124832125 creator A5048209005 @default.
- W3124832125 creator A5050366174 @default.
- W3124832125 creator A5064727312 @default.
- W3124832125 creator A5064750158 @default.
- W3124832125 creator A5069025834 @default.
- W3124832125 creator A5075564166 @default.
- W3124832125 date "2021-01-01" @default.
- W3124832125 modified "2023-09-25" @default.
- W3124832125 title "The Neural Representation of Force across Grasp Types in Motor Cortex of Humans with Tetraplegia" @default.
- W3124832125 cites W1278042599 @default.
- W3124832125 cites W1487392737 @default.
- W3124832125 cites W15228111 @default.
- W3124832125 cites W177112860 @default.
- W3124832125 cites W1799331832 @default.
- W3124832125 cites W180049700 @default.
- W3124832125 cites W1904024272 @default.
- W3124832125 cites W1964897554 @default.
- W3124832125 cites W1966679339 @default.
- W3124832125 cites W1969957364 @default.
- W3124832125 cites W1975093582 @default.
- W3124832125 cites W1976057548 @default.
- W3124832125 cites W1976902850 @default.
- W3124832125 cites W1977241384 @default.
- W3124832125 cites W1985279342 @default.
- W3124832125 cites W1988067967 @default.
- W3124832125 cites W1990636139 @default.
- W3124832125 cites W1997392514 @default.
- W3124832125 cites W2005617065 @default.
- W3124832125 cites W2007324434 @default.
- W3124832125 cites W2009146005 @default.
- W3124832125 cites W2009664245 @default.
- W3124832125 cites W2009700266 @default.
- W3124832125 cites W2010573942 @default.
- W3124832125 cites W2011527020 @default.
- W3124832125 cites W2011836546 @default.
- W3124832125 cites W2012435059 @default.
- W3124832125 cites W2014320934 @default.
- W3124832125 cites W2019662148 @default.
- W3124832125 cites W2019800929 @default.
- W3124832125 cites W2021264442 @default.
- W3124832125 cites W2025882496 @default.
- W3124832125 cites W2033144847 @default.
- W3124832125 cites W2038943721 @default.
- W3124832125 cites W2039105805 @default.
- W3124832125 cites W2040739363 @default.
- W3124832125 cites W2041248708 @default.
- W3124832125 cites W2042425362 @default.
- W3124832125 cites W2043338161 @default.
- W3124832125 cites W2044890387 @default.
- W3124832125 cites W2047679627 @default.
- W3124832125 cites W2055577402 @default.
- W3124832125 cites W2059185381 @default.
- W3124832125 cites W2062159891 @default.
- W3124832125 cites W2063431149 @default.
- W3124832125 cites W2067395123 @default.
- W3124832125 cites W2074378279 @default.
- W3124832125 cites W2079674350 @default.
- W3124832125 cites W2087704839 @default.
- W3124832125 cites W2089318762 @default.
- W3124832125 cites W2093100633 @default.
- W3124832125 cites W2098406191 @default.
- W3124832125 cites W2100483618 @default.
- W3124832125 cites W2101466543 @default.
- W3124832125 cites W2102800711 @default.
- W3124832125 cites W2106006415 @default.
- W3124832125 cites W2114004602 @default.
- W3124832125 cites W2118900276 @default.
- W3124832125 cites W2128945056 @default.
- W3124832125 cites W2135825876 @default.
- W3124832125 cites W2138562519 @default.
- W3124832125 cites W2138608253 @default.
- W3124832125 cites W2144910141 @default.
- W3124832125 cites W2145003473 @default.
- W3124832125 cites W2149331527 @default.
- W3124832125 cites W2152225095 @default.
- W3124832125 cites W2157094999 @default.
- W3124832125 cites W2173992505 @default.
- W3124832125 cites W2179805876 @default.
- W3124832125 cites W2184284293 @default.
- W3124832125 cites W2207462230 @default.
- W3124832125 cites W2271518742 @default.
- W3124832125 cites W2279056185 @default.
- W3124832125 cites W2295175700 @default.
- W3124832125 cites W2295561584 @default.
- W3124832125 cites W2296237976 @default.