Matches in SemOpenAlex for { <https://semopenalex.org/work/W3125082022> ?p ?o ?g. }
- W3125082022 endingPage "157" @default.
- W3125082022 startingPage "149" @default.
- W3125082022 abstract "SARS-CoV-2 infection (COVID-19) has caused a high number of hospitalizations and deaths. There are currently no approved antiviral drugs or vaccine options available for treatment. Patients with severe cases of COVID-19 are receiving supportive care to manage life-threatening symptoms of viral pneumonia and acute respiratory distress syndrome (ARDS). Clinical and pathological evidence suggests that patients with severe COVID-19 infections suffer from cytokine storm syndrome, which leads to unfavorable health outcomes. Unfortunately, the conventional pharmacotherapies for cytokine storm syndrome are associated with immunosuppression and various other side effects that may worsen the patients’ health status and healing capability. This study is to review the literature on how zinc status may affect susceptibility and outcomes of a viral infection, as well as to explore the possible beneficial effects of supplementing zinc to alleviate COVID-19 duration and severity. We propose zinc supplementation as a viable therapeutic approach when used alone or in combination with other drugs to combat cytokine storm syndrome in COVID-19 patients. The supplementation may be especially effective for elderly patients or patients with co-morbidity already deficient in zinc. More level I randomized controlled studies are needed to determine the clinical efficacy of zinc supplementation as a potential low-cost intervention to reduce morbidity and mortality due to pneumonia and ARDS in COVID-19 patients." @default.
- W3125082022 created "2021-02-01" @default.
- W3125082022 creator A5004476964 @default.
- W3125082022 creator A5005638984 @default.
- W3125082022 date "2021-01-13" @default.
- W3125082022 modified "2023-09-27" @default.
- W3125082022 title "Micronutrient zinc roles in adjunctive therapy for COVID-19 by enhancing patients immunoregulation and tolerance to the pathogen" @default.
- W3125082022 cites W139110967 @default.
- W3125082022 cites W1509086826 @default.
- W3125082022 cites W1603804386 @default.
- W3125082022 cites W1747551678 @default.
- W3125082022 cites W1793418802 @default.
- W3125082022 cites W1850016195 @default.
- W3125082022 cites W1925247835 @default.
- W3125082022 cites W1943607432 @default.
- W3125082022 cites W1951544708 @default.
- W3125082022 cites W1971861118 @default.
- W3125082022 cites W1972757665 @default.
- W3125082022 cites W1973409301 @default.
- W3125082022 cites W1976420445 @default.
- W3125082022 cites W1977425207 @default.
- W3125082022 cites W1978190433 @default.
- W3125082022 cites W1982814610 @default.
- W3125082022 cites W1984632019 @default.
- W3125082022 cites W1987682986 @default.
- W3125082022 cites W1988115640 @default.
- W3125082022 cites W1992974015 @default.
- W3125082022 cites W1994217603 @default.
- W3125082022 cites W2000097682 @default.
- W3125082022 cites W2002028073 @default.
- W3125082022 cites W2002419592 @default.
- W3125082022 cites W2005948700 @default.
- W3125082022 cites W2011136641 @default.
- W3125082022 cites W2013422007 @default.
- W3125082022 cites W2014454828 @default.
- W3125082022 cites W2015667478 @default.
- W3125082022 cites W2017530776 @default.
- W3125082022 cites W2019834610 @default.
- W3125082022 cites W2029558262 @default.
- W3125082022 cites W2029631026 @default.
- W3125082022 cites W2029795722 @default.
- W3125082022 cites W2035526149 @default.
- W3125082022 cites W2037868236 @default.
- W3125082022 cites W2039232770 @default.
- W3125082022 cites W2042783249 @default.
- W3125082022 cites W2047425163 @default.
- W3125082022 cites W2048657681 @default.
- W3125082022 cites W2051311307 @default.
- W3125082022 cites W2051432193 @default.
- W3125082022 cites W2055116911 @default.
- W3125082022 cites W2055776778 @default.
- W3125082022 cites W2057835720 @default.
- W3125082022 cites W2058465738 @default.
- W3125082022 cites W2063958461 @default.
- W3125082022 cites W2065405978 @default.
- W3125082022 cites W2068854215 @default.
- W3125082022 cites W2074662949 @default.
- W3125082022 cites W2081371688 @default.
- W3125082022 cites W2083759868 @default.
- W3125082022 cites W2086923184 @default.
- W3125082022 cites W2087356499 @default.
- W3125082022 cites W2088220499 @default.
- W3125082022 cites W2088262395 @default.
- W3125082022 cites W2089034956 @default.
- W3125082022 cites W2090527340 @default.
- W3125082022 cites W2091652649 @default.
- W3125082022 cites W2095915834 @default.
- W3125082022 cites W2096254377 @default.
- W3125082022 cites W2100249667 @default.
- W3125082022 cites W2101225862 @default.
- W3125082022 cites W2102050228 @default.
- W3125082022 cites W2104743514 @default.
- W3125082022 cites W2104773343 @default.
- W3125082022 cites W2107836548 @default.
- W3125082022 cites W2109444056 @default.
- W3125082022 cites W2109530552 @default.
- W3125082022 cites W2110652761 @default.
- W3125082022 cites W2112310296 @default.
- W3125082022 cites W2115394544 @default.
- W3125082022 cites W2115894981 @default.
- W3125082022 cites W2128559379 @default.
- W3125082022 cites W2128825612 @default.
- W3125082022 cites W2129239355 @default.
- W3125082022 cites W2137054533 @default.
- W3125082022 cites W2140877018 @default.
- W3125082022 cites W2141989396 @default.
- W3125082022 cites W2145709076 @default.
- W3125082022 cites W2146643957 @default.
- W3125082022 cites W2151138214 @default.
- W3125082022 cites W2152122395 @default.
- W3125082022 cites W2154552532 @default.
- W3125082022 cites W2159812564 @default.
- W3125082022 cites W2165984319 @default.
- W3125082022 cites W2171479677 @default.
- W3125082022 cites W2174270021 @default.
- W3125082022 cites W2186671145 @default.
- W3125082022 cites W2322226463 @default.
- W3125082022 cites W2324161020 @default.