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- W3125126263 abstract "Abstract Background Adrenal incidentaloma (AI) is the term for any unsuspected lesion of the adrenal gland found by radiologic imaging, usually done for other indications. Although it is consistently recommended that hyper-functional tumor and suspicious malignancy need surgery, the management of patients with small benign non-functional adrenal incidentaloma remains controversial. Here we develop a detailed mathematical decision analysis model comparing the projected management costs for small benign non-functional adrenal incidentaloma. Methods A detailed model was developed that integrates projected costs for a few possible treatment outcomes. Starting values and probabilities were derived from a comprehensive meta-analysis of 1298 patients. Hypothesis testing was performed using sensitivity analysis. Results The model predicts a cost premium for follow-up compared with surgery. The tornado analysis identify the cost of follow-up for once as the most important variables for our model. One-way sensitivity analysis demonstrated that cost equivalence could be met with ¥4359.5 for once follow-up, keeping other factors constant. Conclusion Our models of treatment for small benign non-functional adrenal incidentaloma showed significant cost differences for follow-up vs immediate surgery. The cost of follow-up for once featured threshold values." @default.
- W3125126263 created "2021-02-01" @default.
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- W3125126263 date "2021-01-18" @default.
- W3125126263 modified "2023-09-23" @default.
- W3125126263 title "Modeling the Cost of Management Options for small benign non-functional adrenal incidentaloma: A Decision Tree Analysis" @default.
- W3125126263 doi "https://doi.org/10.21203/rs.3.rs-144432/v1" @default.
- W3125126263 hasPublicationYear "2021" @default.
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