Matches in SemOpenAlex for { <https://semopenalex.org/work/W3125433829> ?p ?o ?g. }
- W3125433829 endingPage "32" @default.
- W3125433829 startingPage "26" @default.
- W3125433829 abstract "BackgroundDaily chlorhexidine bathing has been associated with a reduction in central line-associated bloodstream infections (CLABSI). In the setting of an already established CLABSI surveillance system and an implemented CLABSI prevention bundle, we analysed the effect of daily chlorhexidine bathing in ICU patients on CLABSI incidence and its causative pathogens.MethodsThis was a before-and-after study in intensive care units (ICUs) at a tertiary-care centre in Switzerland. Prospective surveillance of CLABSIs and their aetiologies was established. The intervention consisted of daily chlorhexidine bathing of ICU patients with a central venous catheter. A baseline period of 19 months was followed by an intervention period of 9 months.FindingsA total of 5008 patients were included. In the baseline period a mean CLABSI rate of 2.45/1000 catheter days (95% confidence interval (CI) 1.93–3.07) was observed, followed by 1.00/1000 catheter days (95% CI 0.55–1.67; P<0.001) in the intervention period. Introduction of chlorhexidine bathing was independently associated with a reduced risk of CLABSI (adjusted odds ratio 0.47, 95% CI 0.26–0.84, P=0.011). We did not observe a significant change in aetiology except for an increase of Serratia marcescens in the intervention period.ConclusionsIntroduction of daily chlorhexidine bathing resulted in a decline in CLABSI incidence on ICUs. Starting from a baseline CLABSI rate that can be considered standard in a high-income setting and several measures for CLABSI prevention implemented, chlorhexidine bathing proved helpful for a further reduction. Daily chlorhexidine bathing has been associated with a reduction in central line-associated bloodstream infections (CLABSI). In the setting of an already established CLABSI surveillance system and an implemented CLABSI prevention bundle, we analysed the effect of daily chlorhexidine bathing in ICU patients on CLABSI incidence and its causative pathogens. This was a before-and-after study in intensive care units (ICUs) at a tertiary-care centre in Switzerland. Prospective surveillance of CLABSIs and their aetiologies was established. The intervention consisted of daily chlorhexidine bathing of ICU patients with a central venous catheter. A baseline period of 19 months was followed by an intervention period of 9 months. A total of 5008 patients were included. In the baseline period a mean CLABSI rate of 2.45/1000 catheter days (95% confidence interval (CI) 1.93–3.07) was observed, followed by 1.00/1000 catheter days (95% CI 0.55–1.67; P<0.001) in the intervention period. Introduction of chlorhexidine bathing was independently associated with a reduced risk of CLABSI (adjusted odds ratio 0.47, 95% CI 0.26–0.84, P=0.011). We did not observe a significant change in aetiology except for an increase of Serratia marcescens in the intervention period. Introduction of daily chlorhexidine bathing resulted in a decline in CLABSI incidence on ICUs. Starting from a baseline CLABSI rate that can be considered standard in a high-income setting and several measures for CLABSI prevention implemented, chlorhexidine bathing proved helpful for a further reduction." @default.
- W3125433829 created "2021-02-01" @default.
- W3125433829 creator A5004580216 @default.
- W3125433829 creator A5007238616 @default.
- W3125433829 creator A5013622355 @default.
- W3125433829 creator A5014481168 @default.
- W3125433829 creator A5018368535 @default.
- W3125433829 creator A5019900801 @default.
- W3125433829 creator A5022389576 @default.
- W3125433829 creator A5028463459 @default.
- W3125433829 creator A5084735510 @default.
- W3125433829 date "2021-04-01" @default.
- W3125433829 modified "2023-10-11" @default.
- W3125433829 title "Implementation of daily chlorhexidine bathing in intensive care units for reduction of central line-associated bloodstream infections" @default.
- W3125433829 cites W160168904 @default.
- W3125433829 cites W1995466415 @default.
- W3125433829 cites W2005564986 @default.
- W3125433829 cites W2010849449 @default.
- W3125433829 cites W2031288400 @default.
- W3125433829 cites W2044128618 @default.
- W3125433829 cites W2105157052 @default.
- W3125433829 cites W2136111108 @default.
- W3125433829 cites W2136184219 @default.
- W3125433829 cites W2165661384 @default.
- W3125433829 cites W2328890453 @default.
- W3125433829 cites W2346468312 @default.
- W3125433829 cites W2409575133 @default.
- W3125433829 cites W2560227189 @default.
- W3125433829 cites W2624416245 @default.
- W3125433829 cites W2725253141 @default.
- W3125433829 cites W2892397786 @default.
- W3125433829 cites W2916228011 @default.
- W3125433829 cites W2923334545 @default.
- W3125433829 cites W2936872952 @default.
- W3125433829 cites W2967643260 @default.
- W3125433829 cites W2980444694 @default.
- W3125433829 cites W3000709275 @default.
- W3125433829 cites W3001944039 @default.
- W3125433829 cites W3037613496 @default.
- W3125433829 cites W4230357700 @default.
- W3125433829 cites W4235487047 @default.
- W3125433829 doi "https://doi.org/10.1016/j.jhin.2021.01.007" @default.
- W3125433829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33482298" @default.
- W3125433829 hasPublicationYear "2021" @default.
- W3125433829 type Work @default.
- W3125433829 sameAs 3125433829 @default.
- W3125433829 citedByCount "2" @default.
- W3125433829 countsByYear W31254338292021 @default.
- W3125433829 countsByYear W31254338292022 @default.
- W3125433829 crossrefType "journal-article" @default.
- W3125433829 hasAuthorship W3125433829A5004580216 @default.
- W3125433829 hasAuthorship W3125433829A5007238616 @default.
- W3125433829 hasAuthorship W3125433829A5013622355 @default.
- W3125433829 hasAuthorship W3125433829A5014481168 @default.
- W3125433829 hasAuthorship W3125433829A5018368535 @default.
- W3125433829 hasAuthorship W3125433829A5019900801 @default.
- W3125433829 hasAuthorship W3125433829A5022389576 @default.
- W3125433829 hasAuthorship W3125433829A5028463459 @default.
- W3125433829 hasAuthorship W3125433829A5084735510 @default.
- W3125433829 hasBestOaLocation W31254338291 @default.
- W3125433829 hasConcept C120665830 @default.
- W3125433829 hasConcept C121332964 @default.
- W3125433829 hasConcept C126322002 @default.
- W3125433829 hasConcept C141071460 @default.
- W3125433829 hasConcept C142724271 @default.
- W3125433829 hasConcept C156957248 @default.
- W3125433829 hasConcept C166888038 @default.
- W3125433829 hasConcept C177713679 @default.
- W3125433829 hasConcept C188816634 @default.
- W3125433829 hasConcept C194828623 @default.
- W3125433829 hasConcept C199343813 @default.
- W3125433829 hasConcept C207103383 @default.
- W3125433829 hasConcept C2777084678 @default.
- W3125433829 hasConcept C2778446481 @default.
- W3125433829 hasConcept C2778826615 @default.
- W3125433829 hasConcept C2781267111 @default.
- W3125433829 hasConcept C2987404301 @default.
- W3125433829 hasConcept C44249647 @default.
- W3125433829 hasConcept C61511704 @default.
- W3125433829 hasConcept C71924100 @default.
- W3125433829 hasConceptScore W3125433829C120665830 @default.
- W3125433829 hasConceptScore W3125433829C121332964 @default.
- W3125433829 hasConceptScore W3125433829C126322002 @default.
- W3125433829 hasConceptScore W3125433829C141071460 @default.
- W3125433829 hasConceptScore W3125433829C142724271 @default.
- W3125433829 hasConceptScore W3125433829C156957248 @default.
- W3125433829 hasConceptScore W3125433829C166888038 @default.
- W3125433829 hasConceptScore W3125433829C177713679 @default.
- W3125433829 hasConceptScore W3125433829C188816634 @default.
- W3125433829 hasConceptScore W3125433829C194828623 @default.
- W3125433829 hasConceptScore W3125433829C199343813 @default.
- W3125433829 hasConceptScore W3125433829C207103383 @default.
- W3125433829 hasConceptScore W3125433829C2777084678 @default.
- W3125433829 hasConceptScore W3125433829C2778446481 @default.
- W3125433829 hasConceptScore W3125433829C2778826615 @default.
- W3125433829 hasConceptScore W3125433829C2781267111 @default.
- W3125433829 hasConceptScore W3125433829C2987404301 @default.
- W3125433829 hasConceptScore W3125433829C44249647 @default.