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• W3125528931 abstract "We performed a cross-sectional analysis in adult smokers enrolled from two prospective studies: A randomised controlled trial for tobacco cessation (ESTXENDS, [NCT03938298][1]) and the Swiss Idiopathic Interstitial Pneumonia cohort (Swiss-IIP) [8]. For both cohorts, participants were enrolled consecutively in the pulmonary outpatient clinic and by advertisement between 2016/10/27-2019/11/30. Inclusion criteria were: Age≥18 years, self-reported smoking≥5 cigarettes per day since at least 12 months. Individuals with chronic lung disease, any inhaler medication, or abnormal spirometry defined as FEV1/FVC<0.70 were excluded [9]. The Study was approved by the local ethics committee (KEK BE 246/15, Basec PB 2016-01524; KEK BE 2017-02332); written informed consent was obtained from all participants. Setting: pulmonary outpatient clinic, University Hospital, Bern, Switzerland.Footnotes This manuscript has recently been accepted for publication in the ERJ Open Research . It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: Kurz has nothing to disclose.Conflict of interest: Dr. Frey has nothing to disclose.Conflict of interest: Dr. Auer reports grants from Swiss National Science Foundation, grants from Tobacco Prevention Fund, grants from Swiss Cancer Research, during the conduct of the study.Conflict of interest: Dr. Rodonti has nothing to disclose.Conflict of interest: Dr. Nyilas has nothing to disclose.Conflict of interest: Dr. Pavlov has nothing to disclose.Conflict of interest: Dr. Funke reports grants from Boehringer Ingelheim, from Roche, outside the submitted work.Conflict of interest: Dr. Singer reports personal fees from Novartis, personal fees from Vertex, grants from Swiss Society of Cystic Fibrosis (CFCH), grants from Lungenliga Bern, outside the submitted work. [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03938298&atom=%2Ferjor%2Fearly%2F2021%2F01%2F14%2F23120541.00706-2020.atom" @default.
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• W3125528931 date "2021-01-01" @default.
• W3125528931 modified "2023-10-14" @default.
• W3125528931 title "Influence of ventilation inhomogeneity on diffusing capacity of carbon monoxide in smokers without COPD" @default.
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• W3125528931 doi "https://doi.org/10.1183/23120541.00706-2020" @default.
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