FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3125529952> ?p ?o ?g. }

• W3125529952 endingPage "325" @default.
• W3125529952 startingPage "314" @default.
• W3125529952 abstract "Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic option for patients at risk of thrombosis. DOACs interfere with clot-based testing for the identification of lupus anticoagulant antibodies (LACs) in patients with antiphospholipid syndrome (APS), a common cause of acquired thrombotic disease. Objectives To evaluate a commercially available reagent DOAC-Stop for the removal of DOAC interference encountered in LAC testing. Patients/Methods We collected a cohort of 73 test samples from patients on DOAC therapy identified at a large institutional coagulation laboratory from March to December 2019, along with samples from 40 LAC positive and negative control patients not on therapy. Samples were treated with DOAC-Stop and tested for anti-Xa activity and thrombin time for the removal of apixaban, rivaroxaban, argatroban, and dabigatran activity from patient samples. Treated and untreated samples were tested using the activated partial thromboplastin time, silica clotting time, and dilute Russell’s viper venom time to evaluate the reliability and utility of DOAC-Stop. Results DOAC-Stop markedly reduced DOAC interference from test samples (P < .05). DOAC-Stop had no effect on LAC testing in the absence of DOAC therapy, permitting the identification of all LAC positive and negative controls. DOAC-Stop removed false positives and false negatives resulting from DOAC interference and allows the identification of patients meeting criteria for the diagnosis of APS by LAC testing, as well as the detection of patients on rivaroxaban who are triple positive for APS. Conclusions DOAC-Stop is an effective adjunct for the clinical laboratory faced with DOAC interference in LAC testing." @default.
• W3125529952 created "2021-02-01" @default.
• W3125529952 creator A5014659823 @default.
• W3125529952 creator A5043209053 @default.
• W3125529952 creator A5051947814 @default.
• W3125529952 creator A5082156574 @default.
• W3125529952 creator A5089651942 @default.
• W3125529952 date "2021-02-01" @default.
• W3125529952 modified "2023-10-10" @default.
• W3125529952 title "DOAC‐Stop in lupus anticoagulant testing: Direct oral anticoagulant interference removed in most samples" @default.
• W3125529952 cites W1920351484 @default.
• W3125529952 cites W1963838572 @default.
• W3125529952 cites W1964673028 @default.
• W3125529952 cites W1968663066 @default.
• W3125529952 cites W1970271209 @default.
• W3125529952 cites W1975074770 @default.
• W3125529952 cites W1997970906 @default.
• W3125529952 cites W2006990092 @default.
• W3125529952 cites W2017573410 @default.
• W3125529952 cites W2023929943 @default.
• W3125529952 cites W2035910249 @default.
• W3125529952 cites W2041919675 @default.
• W3125529952 cites W2043265749 @default.
• W3125529952 cites W2044043417 @default.
• W3125529952 cites W2054330426 @default.
• W3125529952 cites W2069797332 @default.
• W3125529952 cites W2098834735 @default.
• W3125529952 cites W2100680349 @default.
• W3125529952 cites W2101979147 @default.
• W3125529952 cites W2122953083 @default.
• W3125529952 cites W2160597832 @default.
• W3125529952 cites W2161749544 @default.
• W3125529952 cites W2198244152 @default.
• W3125529952 cites W2283366147 @default.
• W3125529952 cites W2467570418 @default.
• W3125529952 cites W2520740086 @default.
• W3125529952 cites W2563628618 @default.
• W3125529952 cites W2567538246 @default.
• W3125529952 cites W2615467629 @default.
• W3125529952 cites W2615580953 @default.
• W3125529952 cites W2616931588 @default.
• W3125529952 cites W2622826012 @default.
• W3125529952 cites W2769760280 @default.
• W3125529952 cites W2791992225 @default.
• W3125529952 cites W2792756092 @default.
• W3125529952 cites W2792792272 @default.
• W3125529952 cites W2805959260 @default.
• W3125529952 cites W2813643485 @default.
• W3125529952 cites W2901796260 @default.
• W3125529952 cites W2911868574 @default.
• W3125529952 cites W2943547532 @default.
• W3125529952 cites W2945715692 @default.
• W3125529952 cites W2973927174 @default.
• W3125529952 cites W2995572514 @default.
• W3125529952 cites W3015356890 @default.
• W3125529952 cites W3016995275 @default.
• W3125529952 cites W3024580285 @default.
• W3125529952 cites W3082829636 @default.
• W3125529952 cites W323010064 @default.
• W3125529952 doi "https://doi.org/10.1002/rth2.12472" @default.
• W3125529952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7938630" @default.
• W3125529952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33733031" @default.
• W3125529952 hasPublicationYear "2021" @default.
• W3125529952 type Work @default.
• W3125529952 sameAs 3125529952 @default.
• W3125529952 citedByCount "12" @default.
• W3125529952 countsByYear W31255299522021 @default.
• W3125529952 countsByYear W31255299522022 @default.
• W3125529952 countsByYear W31255299522023 @default.
• W3125529952 crossrefType "journal-article" @default.
• W3125529952 hasAuthorship W3125529952A5014659823 @default.
• W3125529952 hasAuthorship W3125529952A5043209053 @default.
• W3125529952 hasAuthorship W3125529952A5051947814 @default.
• W3125529952 hasAuthorship W3125529952A5082156574 @default.
• W3125529952 hasAuthorship W3125529952A5089651942 @default.
• W3125529952 hasBestOaLocation W31255299521 @default.
• W3125529952 hasConcept C126322002 @default.
• W3125529952 hasConcept C16124881 @default.
• W3125529952 hasConcept C2776301958 @default.
• W3125529952 hasConcept C2777292125 @default.
• W3125529952 hasConcept C2778261982 @default.
• W3125529952 hasConcept C2778382381 @default.
• W3125529952 hasConcept C2778661090 @default.
• W3125529952 hasConcept C2778810321 @default.
• W3125529952 hasConcept C2779161974 @default.
• W3125529952 hasConcept C2779612170 @default.
• W3125529952 hasConcept C2780022809 @default.
• W3125529952 hasConcept C2780638905 @default.
• W3125529952 hasConcept C2780868729 @default.
• W3125529952 hasConcept C71924100 @default.
• W3125529952 hasConcept C89560881 @default.
• W3125529952 hasConceptScore W3125529952C126322002 @default.
• W3125529952 hasConceptScore W3125529952C16124881 @default.
• W3125529952 hasConceptScore W3125529952C2776301958 @default.
• W3125529952 hasConceptScore W3125529952C2777292125 @default.
• W3125529952 hasConceptScore W3125529952C2778261982 @default.
• W3125529952 hasConceptScore W3125529952C2778382381 @default.
• W3125529952 hasConceptScore W3125529952C2778661090 @default.

• next