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- W3125662142 abstract "Abstract We conducted a systematic review of human trials examining the effects of dietary phytochemicals on Nrf2 activation. In accordance with the PRISMA guidelines, Medline, Embase and CAB abstracts were searched for articles from inception until March 2020. Studies in adult humans that measured Nrf2 activation (gene or protein expression changes) following ingestion of a phytochemical, either alone or in combination were included. The study was pre-registered on the Prospero database (Registration Number: CRD42020176121). Twenty-nine full-texts were retrieved and reviewed for analysis; of these, eighteen were included in the systematic review. Most of the included participants were healthy, obese or type 2 diabetics. Study quality was assessed using the Cochrane Collaboration Risk of Bias Assessment tool. Twelve different compounds were examined in the included studies: curcumin, resveratrol and sulforaphane were the most common ( n = 3 each). Approximately half of the studies reported increases in Nrf2 activation ( n = 10); however, many were of poor quality and had an unclear or high risk of bias. There is currently limited evidence that phytochemicals activate Nrf2 in humans. Well controlled human intervention trials are needed to corroborate the findings from in vitro and animal studies." @default.
- W3125662142 created "2021-02-01" @default.
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- W3125662142 date "2021-01-30" @default.
- W3125662142 modified "2023-10-15" @default.
- W3125662142 title "The effect of dietary phytochemicals on nuclear factor erythroid 2-related factor 2 (Nrf2) activation: a systematic review of human intervention trials" @default.
- W3125662142 cites W1587175009 @default.
- W3125662142 cites W1683287975 @default.
- W3125662142 cites W1964986597 @default.
- W3125662142 cites W1965743421 @default.
- W3125662142 cites W1967828638 @default.
- W3125662142 cites W1977920395 @default.
- W3125662142 cites W1978706288 @default.
- W3125662142 cites W1981184057 @default.
- W3125662142 cites W1981425406 @default.
- W3125662142 cites W1990364631 @default.
- W3125662142 cites W1991460472 @default.
- W3125662142 cites W1991631628 @default.
- W3125662142 cites W1999718232 @default.
- W3125662142 cites W2011093918 @default.
- W3125662142 cites W2023536393 @default.
- W3125662142 cites W2025837299 @default.
- W3125662142 cites W2026212248 @default.
- W3125662142 cites W2026711456 @default.
- W3125662142 cites W2036948472 @default.
- W3125662142 cites W2037299745 @default.
- W3125662142 cites W2042549883 @default.
- W3125662142 cites W2048536263 @default.
- W3125662142 cites W2049398364 @default.
- W3125662142 cites W2049578720 @default.
- W3125662142 cites W2053350368 @default.
- W3125662142 cites W2061142443 @default.
- W3125662142 cites W2061184965 @default.
- W3125662142 cites W2066472053 @default.
- W3125662142 cites W2068878269 @default.
- W3125662142 cites W2070531739 @default.
- W3125662142 cites W2072329234 @default.
- W3125662142 cites W2074132213 @default.
- W3125662142 cites W2075037447 @default.
- W3125662142 cites W2085516978 @default.
- W3125662142 cites W2091319093 @default.
- W3125662142 cites W2096099635 @default.
- W3125662142 cites W2098923148 @default.
- W3125662142 cites W2099808035 @default.
- W3125662142 cites W2105234557 @default.
- W3125662142 cites W2105778142 @default.
- W3125662142 cites W2113576996 @default.
- W3125662142 cites W2113605815 @default.
- W3125662142 cites W2114767658 @default.
- W3125662142 cites W2114927851 @default.
- W3125662142 cites W2115338196 @default.
- W3125662142 cites W2116537033 @default.
- W3125662142 cites W2124122523 @default.
- W3125662142 cites W2124569198 @default.
- W3125662142 cites W212489684 @default.
- W3125662142 cites W2126635195 @default.
- W3125662142 cites W2128473487 @default.
- W3125662142 cites W2134349613 @default.
- W3125662142 cites W2134669826 @default.
- W3125662142 cites W2136443800 @default.
- W3125662142 cites W2141033229 @default.
- W3125662142 cites W2163402696 @default.
- W3125662142 cites W2165201727 @default.
- W3125662142 cites W2207241376 @default.
- W3125662142 cites W2260123459 @default.
- W3125662142 cites W2275001158 @default.
- W3125662142 cites W2282124923 @default.
- W3125662142 cites W2283775419 @default.
- W3125662142 cites W2294952118 @default.
- W3125662142 cites W2315952767 @default.
- W3125662142 cites W2316568196 @default.
- W3125662142 cites W2323962882 @default.
- W3125662142 cites W2338551699 @default.
- W3125662142 cites W2342374551 @default.
- W3125662142 cites W2477967355 @default.
- W3125662142 cites W2491926929 @default.
- W3125662142 cites W2517253804 @default.
- W3125662142 cites W2517587753 @default.
- W3125662142 cites W2520217702 @default.
- W3125662142 cites W2521574223 @default.
- W3125662142 cites W2549382977 @default.
- W3125662142 cites W2553354647 @default.
- W3125662142 cites W2604612121 @default.
- W3125662142 cites W2625976727 @default.
- W3125662142 cites W2626441385 @default.
- W3125662142 cites W2727154980 @default.
- W3125662142 cites W2757737297 @default.
- W3125662142 cites W2767485891 @default.
- W3125662142 cites W2775355816 @default.
- W3125662142 cites W2784789637 @default.
- W3125662142 cites W2784922874 @default.
- W3125662142 cites W2790475021 @default.
- W3125662142 cites W2790931380 @default.
- W3125662142 cites W2794103257 @default.