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- W3125778071 abstract "Herein we report the multicomponent synthesis of the bis(indolyl)methane derivatives in a ball mill. The reaction was carried out under solvent-free conditions using only the Lewis acid-surfactant-SiO2 composite nanocatalyst (LASSC) prepared in situ. The unsymmetrical bis(indolyl) methane derivatives containing nitro or fluorine substitution with a yield of 72%–92% were obtained in a short reaction time. Within we verified that under the action of the combined catalyst of AlCl3·6H2O + SDS + SiO2, the method of preparing unsymmetrical bis(indolyl)methane by mechanical grinding without solvent has obvious advantages. Finally, we inspected that the catalysis system can be used eight times without a significant decrease in activity." @default.
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- W3125778071 date "2021-01-27" @default.
- W3125778071 modified "2023-09-24" @default.
- W3125778071 title "Solvent-free multi-component synthesis of unsymmetrical bis(indolyl)alkanes with Lewis acid-surfactant-SiO<sub>2</sub> as nanocatalyst" @default.
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- W3125778071 doi "https://doi.org/10.1080/00397911.2021.1874016" @default.
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