Matches in SemOpenAlex for { <https://semopenalex.org/work/W3125868029> ?p ?o ?g. }
- W3125868029 abstract "Leaf morphogenesis involves cell division, expansion, and differentiation in the developing leaf, which take place at different rates and at different positions along the medio-lateral and proximal-distal leaf axes. The gene expression changes that control cell fate along these axes remain elusive due to difficulties in precisely isolating tissues. Here, we combined rigorous early leaf characterization, laser capture microdissection, and transcriptomic sequencing to ask how gene expression patterns regulate early leaf morphogenesis in wild-type tomato (Solanum lycopersicum) and the leaf morphogenesis mutant trifoliate. We observed transcriptional regulation of cell differentiation along the proximal-distal axis and identified molecular signatures delineating the classically defined marginal meristem/blastozone region during early leaf development. We describe the role of endoreduplication during leaf development, when and where leaf cells first achieve photosynthetic competency, and the regulation of auxin transport and signaling along the leaf axes. Knockout mutants of BLADE-ON-PETIOLE2 exhibited ectopic shoot apical meristem formation on leaves, highlighting the role of this gene in regulating margin tissue identity. We mapped gene expression signatures in specific leaf domains and evaluated the role of each domain in conferring indeterminacy and permitting blade outgrowth. Finally, we generated a global gene expression atlas of the early developing compound leaf." @default.
- W3125868029 created "2021-02-01" @default.
- W3125868029 creator A5012316187 @default.
- W3125868029 creator A5030752050 @default.
- W3125868029 creator A5053189630 @default.
- W3125868029 creator A5056172303 @default.
- W3125868029 creator A5073397759 @default.
- W3125868029 date "2020-12-02" @default.
- W3125868029 modified "2023-10-16" @default.
- W3125868029 title "Spatial transcriptional signatures define margin morphogenesis along the proximal–distal and medio-lateral axes in tomato (<i>Solanum lycopersicum</i>) leaves" @default.
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