Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126183178> ?p ?o ?g. }
- W3126183178 abstract "After initial introduction for B-cell lymphomas as adjuvant therapies to established cancer treatments, immune checkpoint inhibitors and other immunotherapies are now integrated in mainstream regimens, both in adult and pediatric patients. We here provide an overview of the current status of combination therapies for B-cell lymphoma, by in-depth analysis of combination therapy trials registered between 2015-2020. Our analysis provides new insight into the rapid evolution in lymphoma treatment, as propelled by new additions to the treatment arsenal. We conclude with prospects on upcoming clinical trials which will likely use systematic testing approaches of more combinations of established chemotherapy regimens with new agents, as well as new combinations of immunotherapy and targeted therapy. Future trials will be set up as basket or umbrella-type trials to facilitate the evaluation of new drugs targeting specific genetic changes in the tumor or associated immune microenvironment. As such, lymphoma patients will benefit by receiving more tailored treatment that is based on synergistic effects of chemotherapy combined with new agents targeting specific aspects of tumor biology and the immune system." @default.
- W3126183178 created "2021-02-15" @default.
- W3126183178 creator A5036407951 @default.
- W3126183178 creator A5047787212 @default.
- W3126183178 creator A5049650517 @default.
- W3126183178 creator A5085549939 @default.
- W3126183178 date "2021-01-01" @default.
- W3126183178 modified "2023-10-02" @default.
- W3126183178 title "Upcoming immunotherapeutic combinations for B-cell lymphoma" @default.
- W3126183178 cites W1509384822 @default.
- W3126183178 cites W1516453481 @default.
- W3126183178 cites W1949313310 @default.
- W3126183178 cites W1954637983 @default.
- W3126183178 cites W1973091654 @default.
- W3126183178 cites W1986354050 @default.
- W3126183178 cites W1988855108 @default.
- W3126183178 cites W1990765152 @default.
- W3126183178 cites W1999088487 @default.
- W3126183178 cites W2000609012 @default.
- W3126183178 cites W2003262666 @default.
- W3126183178 cites W2011228017 @default.
- W3126183178 cites W2012228539 @default.
- W3126183178 cites W2012959199 @default.
- W3126183178 cites W2013909810 @default.
- W3126183178 cites W2026861011 @default.
- W3126183178 cites W2032166347 @default.
- W3126183178 cites W2041672829 @default.
- W3126183178 cites W2044352858 @default.
- W3126183178 cites W2049873925 @default.
- W3126183178 cites W2055352702 @default.
- W3126183178 cites W2059409197 @default.
- W3126183178 cites W2070487917 @default.
- W3126183178 cites W2075875145 @default.
- W3126183178 cites W2077481416 @default.
- W3126183178 cites W2090422859 @default.
- W3126183178 cites W2094958168 @default.
- W3126183178 cites W2096764404 @default.
- W3126183178 cites W2120426523 @default.
- W3126183178 cites W2120775216 @default.
- W3126183178 cites W2125616358 @default.
- W3126183178 cites W2127018518 @default.
- W3126183178 cites W2132258376 @default.
- W3126183178 cites W2140828776 @default.
- W3126183178 cites W2149436029 @default.
- W3126183178 cites W2153558008 @default.
- W3126183178 cites W2155256323 @default.
- W3126183178 cites W2163175900 @default.
- W3126183178 cites W2167355583 @default.
- W3126183178 cites W2171524684 @default.
- W3126183178 cites W2172960056 @default.
- W3126183178 cites W2187899653 @default.
- W3126183178 cites W2279127916 @default.
- W3126183178 cites W2321985702 @default.
- W3126183178 cites W2332991185 @default.
- W3126183178 cites W2335061472 @default.
- W3126183178 cites W2337659275 @default.
- W3126183178 cites W2347131556 @default.
- W3126183178 cites W2407407749 @default.
- W3126183178 cites W2416038770 @default.
- W3126183178 cites W2469555883 @default.
- W3126183178 cites W2476838381 @default.
- W3126183178 cites W2500482667 @default.
- W3126183178 cites W2536322725 @default.
- W3126183178 cites W2568946517 @default.
- W3126183178 cites W2591709377 @default.
- W3126183178 cites W2592133876 @default.
- W3126183178 cites W2598483496 @default.
- W3126183178 cites W2605009867 @default.
- W3126183178 cites W2611933383 @default.
- W3126183178 cites W2740576505 @default.
- W3126183178 cites W2761807003 @default.
- W3126183178 cites W2775803967 @default.
- W3126183178 cites W2794872274 @default.
- W3126183178 cites W2805632139 @default.
- W3126183178 cites W2805689516 @default.
- W3126183178 cites W2810840907 @default.
- W3126183178 cites W2889297222 @default.
- W3126183178 cites W2897167658 @default.
- W3126183178 cites W2898415660 @default.
- W3126183178 cites W2903281422 @default.
- W3126183178 cites W2903669497 @default.
- W3126183178 cites W2906255446 @default.
- W3126183178 cites W2909334052 @default.
- W3126183178 cites W2922163396 @default.
- W3126183178 cites W2938889495 @default.
- W3126183178 cites W2946486395 @default.
- W3126183178 cites W2950071015 @default.
- W3126183178 cites W2951100101 @default.
- W3126183178 cites W2951720456 @default.
- W3126183178 cites W2952129287 @default.
- W3126183178 cites W2953388521 @default.
- W3126183178 cites W2966190920 @default.
- W3126183178 cites W2969230807 @default.
- W3126183178 cites W2970124991 @default.
- W3126183178 cites W2984927918 @default.
- W3126183178 cites W2986196170 @default.
- W3126183178 cites W2995135436 @default.
- W3126183178 cites W2995841997 @default.
- W3126183178 cites W3000179278 @default.
- W3126183178 cites W3003316051 @default.