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• W3126329361 abstract "Waterhouse-Friderichsen syndrome (WFS), defined as severe adrenal insufficiency due to bilateral adrenal gland haemorrhagic necrosis, occurred in a 59-year-old woman. An underlying serogroup Y Neisseria meningitidis (NM) infection was diagnosed, with a rapid progression to purpura fulminans, disseminated intravascular coagulation and WFS. Intensive treatment including fluid resuscitation, broad-spectrum antibiotic therapy, ventilatory support, platelet and factor replacement were administered. The meningococcaemia in the presence of WFS had a fulminant progression, leading to a fatal outcome within 24 hours of symptom onset. This case details the diagnosis and management challenges of the WFS, a rare complication of NM septicaemia, and describes the identification of a NM serogroup that is rare in Portugal in middle-aged patients." @default.
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• W3126329361 date "2021-02-01" @default.
• W3126329361 modified "2023-10-18" @default.
• W3126329361 title "Fatal Waterhouse-Friderichsen syndrome in an adult due to serogroup Y <i>Neisseria meningitidis</i>" @default.
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• W3126329361 doi "https://doi.org/10.1136/bcr-2020-238670" @default.
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