Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126348530> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W3126348530 abstract "Abstract BackgrondWe aimed to describe 25-hydroxyvitamin D [25(OH) D] and carcinoembryonic antigen association levels in patients with locally advanced colorectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT).MethodsBetween July 2012 and September 2018, the records of 92 stage II/III colorectal cancer patients with treated with nCRT followed by radical surgery were reviewed retrospectively. Enzyme-linked immunosorbent assay (ELISA) and chemiluminescence immunoassay was used to analyze the patient’s carcinoembryonic antigen (CEA) and 25(OH) D concentrations in serum.ResultsThe serum levels of 25(OH) D in patients were significantly lower than healthy individuals, just like CEA levels were significantly higher than healthy individuals. The serum CEA in pre-nCRT was significantly lower than in post-nCRT patients, while the serum 25(OH) D from pre-nCRT patients was significantly higher than post-nCRT patients. Our results showed that the pre-nCRT CEA and 25(OH) D level is a risk factor of LARC. ConclusionsNeoadjuvant chemoradiotherapy induces a fall in circulating25(OH) D and carcinoembryonic antigen (CEA). Plasma 25 (OH) D levels is a prognostic biomarker with low 25(OH) D associated with poorer survival. Thus, serum 25(OH) D and CEA levels might be of value in evaluating the pathogenesis and risk of LARC in the future. Moreover, serum CEA or 25(OH) D levels were associated with patient's clinical and pathological features providing data for risk and prognostic prediction." @default.
- W3126348530 created "2021-02-15" @default.
- W3126348530 creator A5015825081 @default.
- W3126348530 creator A5016078546 @default.
- W3126348530 creator A5040019000 @default.
- W3126348530 creator A5045112676 @default.
- W3126348530 creator A5062780200 @default.
- W3126348530 creator A5079048148 @default.
- W3126348530 creator A5082329270 @default.
- W3126348530 creator A5084161888 @default.
- W3126348530 date "2021-02-08" @default.
- W3126348530 modified "2023-09-23" @default.
- W3126348530 title "The Association of Serum 25-Hydroxyvitamin D and Carcinoembryonic Antigen in Locally Advanced Colorectal Cancer With Neoadjuvant Chemoradiotherapy" @default.
- W3126348530 doi "https://doi.org/10.21203/rs.3.rs-165466/v1" @default.
- W3126348530 hasPublicationYear "2021" @default.
- W3126348530 type Work @default.
- W3126348530 sameAs 3126348530 @default.
- W3126348530 citedByCount "0" @default.
- W3126348530 crossrefType "posted-content" @default.
- W3126348530 hasAuthorship W3126348530A5015825081 @default.
- W3126348530 hasAuthorship W3126348530A5016078546 @default.
- W3126348530 hasAuthorship W3126348530A5040019000 @default.
- W3126348530 hasAuthorship W3126348530A5045112676 @default.
- W3126348530 hasAuthorship W3126348530A5062780200 @default.
- W3126348530 hasAuthorship W3126348530A5079048148 @default.
- W3126348530 hasAuthorship W3126348530A5082329270 @default.
- W3126348530 hasAuthorship W3126348530A5084161888 @default.
- W3126348530 hasBestOaLocation W31263485301 @default.
- W3126348530 hasConcept C121608353 @default.
- W3126348530 hasConcept C126322002 @default.
- W3126348530 hasConcept C143998085 @default.
- W3126348530 hasConcept C146357865 @default.
- W3126348530 hasConcept C151730666 @default.
- W3126348530 hasConcept C185592680 @default.
- W3126348530 hasConcept C2777387746 @default.
- W3126348530 hasConcept C2778424827 @default.
- W3126348530 hasConcept C2781197716 @default.
- W3126348530 hasConcept C526805850 @default.
- W3126348530 hasConcept C55493867 @default.
- W3126348530 hasConcept C71924100 @default.
- W3126348530 hasConcept C86803240 @default.
- W3126348530 hasConcept C90924648 @default.
- W3126348530 hasConceptScore W3126348530C121608353 @default.
- W3126348530 hasConceptScore W3126348530C126322002 @default.
- W3126348530 hasConceptScore W3126348530C143998085 @default.
- W3126348530 hasConceptScore W3126348530C146357865 @default.
- W3126348530 hasConceptScore W3126348530C151730666 @default.
- W3126348530 hasConceptScore W3126348530C185592680 @default.
- W3126348530 hasConceptScore W3126348530C2777387746 @default.
- W3126348530 hasConceptScore W3126348530C2778424827 @default.
- W3126348530 hasConceptScore W3126348530C2781197716 @default.
- W3126348530 hasConceptScore W3126348530C526805850 @default.
- W3126348530 hasConceptScore W3126348530C55493867 @default.
- W3126348530 hasConceptScore W3126348530C71924100 @default.
- W3126348530 hasConceptScore W3126348530C86803240 @default.
- W3126348530 hasConceptScore W3126348530C90924648 @default.
- W3126348530 hasLocation W31263485301 @default.
- W3126348530 hasOpenAccess W3126348530 @default.
- W3126348530 hasPrimaryLocation W31263485301 @default.
- W3126348530 hasRelatedWork W1959704305 @default.
- W3126348530 hasRelatedWork W1984008247 @default.
- W3126348530 hasRelatedWork W2381416288 @default.
- W3126348530 hasRelatedWork W2809905798 @default.
- W3126348530 hasRelatedWork W2810213317 @default.
- W3126348530 hasRelatedWork W2903758136 @default.
- W3126348530 hasRelatedWork W3025365092 @default.
- W3126348530 hasRelatedWork W3117991076 @default.
- W3126348530 hasRelatedWork W4321610511 @default.
- W3126348530 hasRelatedWork W4363648070 @default.
- W3126348530 isParatext "false" @default.
- W3126348530 isRetracted "false" @default.
- W3126348530 magId "3126348530" @default.
- W3126348530 workType "article" @default.