FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126533916> ?p ?o ?g. }

• W3126533916 abstract "Abstract Background Stereotactic radiosurgery (SRS) has been recognized as a first-line treatment option for small to moderate sized vestibular schwannoma (VS). Our aim is to evaluate the impact of SRS doses and other patient and disease characteristics on vestibular function in patients with VS. Methods Data on VS patients treated with single-fraction SRS to 12 Gy were retrospectively reviewed. No dose constraints were given to the vestibule during optimization in treatment planning. Patient and tumor characteristics, pre- and post-SRS vestibular examination results and patient-reported dizziness were assessed from patient records. Results Fifty-three patients were analyzed. Median follow-up was 32 months (range, 6–79). The median minimum, mean and maximum vestibular doses were 2.6 ± 1.6 Gy, 6.7 ± 2.8 Gy, and 11 ± 3.6 Gy, respectively. On univariate analysis, Koos grade ( p = 0.04; OR: 3.45; 95% CI 1.01–11.81), tumor volume (median 6.1 cm 3 ; range, 0.8–38; p = 0.01; OR: 4.85; 95% CI 1.43–16.49), presence of pre-SRS dizziness ( p = 0.02; OR: 3.98; 95% CI 1.19–13.24) and minimum vestibular dose ( p = 0.033; OR: 1.55; 95% CI 1.03–2.32) showed a significant association with patient-reported dizziness. On multivariate analysis, minimum vestibular dose remained significant ( p = 0.02; OR: 1.75; 95% CI 1.05–2.89). Patients with improved caloric function had received significantly lower mean (1.5 ± 0.7 Gy, p = 0.01) and maximum doses (4 ± 1.5 Gy, p = 0.01) to the vestibule. Conclusions Our results reveal that 5 Gy and above minimum vestibular doses significantly worsened dizziness. Additionally, mean and maximum doses received by the vestibule were significantly lower in patients who had improved caloric function. Further investigations are needed to determine dose-volume parameters and their effects on vestibular toxicity." @default.
• W3126533916 created "2021-02-15" @default.
• W3126533916 creator A5005906628 @default.
• W3126533916 creator A5009960539 @default.
• W3126533916 creator A5023232540 @default.
• W3126533916 creator A5027139745 @default.
• W3126533916 creator A5030272372 @default.
• W3126533916 creator A5030503449 @default.
• W3126533916 creator A5033862514 @default.
• W3126533916 creator A5055250459 @default.
• W3126533916 creator A5057875617 @default.
• W3126533916 creator A5076792042 @default.
• W3126533916 creator A5079126169 @default.
• W3126533916 creator A5085777557 @default.
• W3126533916 date "2021-03-26" @default.
• W3126533916 modified "2023-10-17" @default.
• W3126533916 title "Vestibular dose correlates with dizziness after radiosurgery for the treatment of vestibular schwannoma" @default.
• W3126533916 cites W1479828585 @default.
• W3126533916 cites W1516700919 @default.
• W3126533916 cites W1548611712 @default.
• W3126533916 cites W1557845873 @default.
• W3126533916 cites W1593463330 @default.
• W3126533916 cites W1727822242 @default.
• W3126533916 cites W1998372696 @default.
• W3126533916 cites W2000721890 @default.
• W3126533916 cites W2008945022 @default.
• W3126533916 cites W2010838822 @default.
• W3126533916 cites W2013483165 @default.
• W3126533916 cites W2015911277 @default.
• W3126533916 cites W2024900421 @default.
• W3126533916 cites W2027750478 @default.
• W3126533916 cites W2029018130 @default.
• W3126533916 cites W2041569058 @default.
• W3126533916 cites W2048418172 @default.
• W3126533916 cites W2050103314 @default.
• W3126533916 cites W2069352960 @default.
• W3126533916 cites W2116189216 @default.
• W3126533916 cites W2164463435 @default.
• W3126533916 cites W2332137791 @default.
• W3126533916 cites W2791906227 @default.
• W3126533916 cites W2804715948 @default.
• W3126533916 cites W2809241172 @default.
• W3126533916 cites W2888360922 @default.
• W3126533916 cites W347867241 @default.
• W3126533916 cites W4362066024 @default.
• W3126533916 doi "https://doi.org/10.1186/s13014-021-01793-7" @default.
• W3126533916 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7995572" @default.
• W3126533916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33771181" @default.
• W3126533916 hasPublicationYear "2021" @default.
• W3126533916 type Work @default.
• W3126533916 sameAs 3126533916 @default.
• W3126533916 citedByCount "5" @default.
• W3126533916 countsByYear W31265339162022 @default.
• W3126533916 countsByYear W31265339162023 @default.
• W3126533916 crossrefType "journal-article" @default.
• W3126533916 hasAuthorship W3126533916A5005906628 @default.
• W3126533916 hasAuthorship W3126533916A5009960539 @default.
• W3126533916 hasAuthorship W3126533916A5023232540 @default.
• W3126533916 hasAuthorship W3126533916A5027139745 @default.
• W3126533916 hasAuthorship W3126533916A5030272372 @default.
• W3126533916 hasAuthorship W3126533916A5030503449 @default.
• W3126533916 hasAuthorship W3126533916A5033862514 @default.
• W3126533916 hasAuthorship W3126533916A5055250459 @default.
• W3126533916 hasAuthorship W3126533916A5057875617 @default.
• W3126533916 hasAuthorship W3126533916A5076792042 @default.
• W3126533916 hasAuthorship W3126533916A5079126169 @default.
• W3126533916 hasAuthorship W3126533916A5085777557 @default.
• W3126533916 hasBestOaLocation W31265339161 @default.
• W3126533916 hasConcept C126322002 @default.
• W3126533916 hasConcept C126838900 @default.
• W3126533916 hasConcept C141071460 @default.
• W3126533916 hasConcept C144301174 @default.
• W3126533916 hasConcept C190041318 @default.
• W3126533916 hasConcept C2780387249 @default.
• W3126533916 hasConcept C2780858735 @default.
• W3126533916 hasConcept C2781447767 @default.
• W3126533916 hasConcept C2989005 @default.
• W3126533916 hasConcept C38180746 @default.
• W3126533916 hasConcept C452148 @default.
• W3126533916 hasConcept C509974204 @default.
• W3126533916 hasConcept C71924100 @default.
• W3126533916 hasConceptScore W3126533916C126322002 @default.
• W3126533916 hasConceptScore W3126533916C126838900 @default.
• W3126533916 hasConceptScore W3126533916C141071460 @default.
• W3126533916 hasConceptScore W3126533916C144301174 @default.
• W3126533916 hasConceptScore W3126533916C190041318 @default.
• W3126533916 hasConceptScore W3126533916C2780387249 @default.
• W3126533916 hasConceptScore W3126533916C2780858735 @default.
• W3126533916 hasConceptScore W3126533916C2781447767 @default.
• W3126533916 hasConceptScore W3126533916C2989005 @default.
• W3126533916 hasConceptScore W3126533916C38180746 @default.
• W3126533916 hasConceptScore W3126533916C452148 @default.
• W3126533916 hasConceptScore W3126533916C509974204 @default.
• W3126533916 hasConceptScore W3126533916C71924100 @default.
• W3126533916 hasFunder F4320320924 @default.
• W3126533916 hasIssue "1" @default.
• W3126533916 hasLocation W31265339161 @default.
• W3126533916 hasLocation W31265339162 @default.
• W3126533916 hasLocation W31265339163 @default.
• W3126533916 hasLocation W31265339164 @default.

• next