FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126690744> ?p ?o ?g. }

• W3126690744 endingPage "506" @default.
• W3126690744 startingPage "496" @default.
• W3126690744 abstract "Papillary thyroid carcinoma (PTC) is a differentiated type of thyroid malignancy with a high incidence. Long non-coding RNA (lncRNA) DUXAP8 has been reported to participate in the proliferation, migration, and invasion of several cancer types. However, its association with PTC has not yet been reported. The current study aimed to investigate the role of DUXAP8 in PTC and revealed the underlying mechanisms. The expression of DUXAP8 was knocked down in two PTC cell lines and the effects of DUXAP8 on the PTC biological behavior were examined by cell counting kit-8 (CCK-8), wound healing, and transwell invasion assays. Luciferase reporter assay was used to detect the binding activity between miR-223-3p and DUXAP8. We found that knockdown of DUXAP8 inhibited the proliferation, migration, and invasion of PTC cells. DUXAP8 could sponge miR-223-3p through the specific binding site. CXCR4 was a target of miR-223-3p. The malignant phenotypes of the PTC cells were suppressed by the over-expression of miR-223-3p. Moreover, miR-223-3p inhibition or CXCR4 over-expression partly restored the proliferation, migration, and invasion activities of DUXAP8-downregulated PTC cells. The results evidenced that DUXAP8 acted as an oncogene in PTC, these effects seemed to partly dependent on the miR-223-3p/CXCR4 axis." @default.
• W3126690744 created "2021-02-15" @default.
• W3126690744 creator A5021293751 @default.
• W3126690744 creator A5047725424 @default.
• W3126690744 creator A5051086590 @default.
• W3126690744 creator A5057161101 @default.
• W3126690744 creator A5072728710 @default.
• W3126690744 creator A5082753869 @default.
• W3126690744 creator A5087494135 @default.
• W3126690744 date "2021-01-01" @default.
• W3126690744 modified "2023-10-02" @default.
• W3126690744 title "Long non-coding RNA DUXAP8 promotes the cell proliferation, migration, and invasion of papillary thyroid carcinoma via miR-223-3p mediated regulation of CXCR4" @default.
• W3126690744 cites W1438161774 @default.
• W3126690744 cites W1965051557 @default.
• W3126690744 cites W2007222816 @default.
• W3126690744 cites W2023624246 @default.
• W3126690744 cites W2033882181 @default.
• W3126690744 cites W2040268038 @default.
• W3126690744 cites W2046387002 @default.
• W3126690744 cites W2059191987 @default.
• W3126690744 cites W2059357290 @default.
• W3126690744 cites W2069792474 @default.
• W3126690744 cites W2091161969 @default.
• W3126690744 cites W2292817566 @default.
• W3126690744 cites W2335889055 @default.
• W3126690744 cites W2337756535 @default.
• W3126690744 cites W2468216259 @default.
• W3126690744 cites W2489129184 @default.
• W3126690744 cites W2573592265 @default.
• W3126690744 cites W2612583081 @default.
• W3126690744 cites W2760884697 @default.
• W3126690744 cites W2762922351 @default.
• W3126690744 cites W2769834144 @default.
• W3126690744 cites W2782729374 @default.
• W3126690744 cites W2782830014 @default.
• W3126690744 cites W2793740075 @default.
• W3126690744 cites W2885548039 @default.
• W3126690744 cites W2896411726 @default.
• W3126690744 cites W2955825471 @default.
• W3126690744 cites W2956163246 @default.
• W3126690744 cites W2973985163 @default.
• W3126690744 cites W2978836141 @default.
• W3126690744 cites W2996078815 @default.
• W3126690744 cites W2996143563 @default.
• W3126690744 cites W3026496288 @default.
• W3126690744 cites W3044310140 @default.
• W3126690744 cites W3044857617 @default.
• W3126690744 cites W3044916628 @default.
• W3126690744 cites W3109810596 @default.
• W3126690744 cites W4236146633 @default.
• W3126690744 doi "https://doi.org/10.1080/21655979.2021.1882134" @default.
• W3126690744 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8291844" @default.
• W3126690744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33522355" @default.
• W3126690744 hasPublicationYear "2021" @default.
• W3126690744 type Work @default.
• W3126690744 sameAs 3126690744 @default.
• W3126690744 citedByCount "21" @default.
• W3126690744 countsByYear W31266907442021 @default.
• W3126690744 countsByYear W31266907442022 @default.
• W3126690744 countsByYear W31266907442023 @default.
• W3126690744 crossrefType "journal-article" @default.
• W3126690744 hasAuthorship W3126690744A5021293751 @default.
• W3126690744 hasAuthorship W3126690744A5047725424 @default.
• W3126690744 hasAuthorship W3126690744A5051086590 @default.
• W3126690744 hasAuthorship W3126690744A5057161101 @default.
• W3126690744 hasAuthorship W3126690744A5072728710 @default.
• W3126690744 hasAuthorship W3126690744A5082753869 @default.
• W3126690744 hasAuthorship W3126690744A5087494135 @default.
• W3126690744 hasBestOaLocation W31266907441 @default.
• W3126690744 hasConcept C104317684 @default.
• W3126690744 hasConcept C111335760 @default.
• W3126690744 hasConcept C129470790 @default.
• W3126690744 hasConcept C13373296 @default.
• W3126690744 hasConcept C134018914 @default.
• W3126690744 hasConcept C1491633281 @default.
• W3126690744 hasConcept C170493617 @default.
• W3126690744 hasConcept C173396325 @default.
• W3126690744 hasConcept C2781018059 @default.
• W3126690744 hasConcept C29537977 @default.
• W3126690744 hasConcept C2993294228 @default.
• W3126690744 hasConcept C502942594 @default.
• W3126690744 hasConcept C526584372 @default.
• W3126690744 hasConcept C54009773 @default.
• W3126690744 hasConcept C54355233 @default.
• W3126690744 hasConcept C62112901 @default.
• W3126690744 hasConcept C62203573 @default.
• W3126690744 hasConcept C67705224 @default.
• W3126690744 hasConcept C81885089 @default.
• W3126690744 hasConcept C86803240 @default.
• W3126690744 hasConceptScore W3126690744C104317684 @default.
• W3126690744 hasConceptScore W3126690744C111335760 @default.
• W3126690744 hasConceptScore W3126690744C129470790 @default.
• W3126690744 hasConceptScore W3126690744C13373296 @default.
• W3126690744 hasConceptScore W3126690744C134018914 @default.
• W3126690744 hasConceptScore W3126690744C1491633281 @default.
• W3126690744 hasConceptScore W3126690744C170493617 @default.
• W3126690744 hasConceptScore W3126690744C173396325 @default.
• W3126690744 hasConceptScore W3126690744C2781018059 @default.

• next