FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126787427> ?p ?o ?g. }

• W3126787427 endingPage "148" @default.
• W3126787427 startingPage "136" @default.
• W3126787427 abstract "The aim of the present study was to identify the potential risk of circulating-HPV-DNA in non-small cell lung cancer (NSCLC) and to analyze abnormally expressed miRNAs in circulating HPV-DNA-positive NSCLC. HPV universal primers were used to detect the presence of HPV-DNA in the peripheral blood of 100 patients with NSCLC. The relationship between circulating-HPV-DNA and NSCLC patients characteristics was analyzed. Then, eight differentially expressed miRNAs in NSCLC were screened based on the TCGA database. The levels of miRNAs in circulating HPV-DNA-positive NSCLC patients were detected by real-time quantitative PCR. ROC curves were generated to evaluate the diagnostic performance. Circulating-HPV-DNA was found in 16 patients. The proportion of HPV-DNA-positive patients with poorly differentiated NSCLC, advanced lung cancer and lymph node metastasis was higher than that of HPV-DNA-negative patients. The levels of miR-183, miR-210 and miR-182 were significantly higher and miR-144 was significantly lower in HPV-DNA-positive NSCLC than those in HPV-DNA-negative NSCLC patients. When using a single miRNA to identify circulating HPV-DNA-positive NSCLC patients, miR-210 had a higher area under the ROC curve (AUC) than other miRNAs, and its sensitivity and specificity were also higher. In addition, the combination of two miRNAs was more effective than a single miRNA. Among them, miR-210+ miR-144 had the highest AUC value and showed the best prediction performance. Circulating-HPV-DNA may serve as a risk factor in NSCLC. Plasma miR-183, miR-210, miR-182 and miR-144 can be used as reliable biomarkers to identify circulating HPV-DNA-positive NSCLC." @default.
• W3126787427 created "2021-02-15" @default.
• W3126787427 creator A5000868340 @default.
• W3126787427 creator A5003518372 @default.
• W3126787427 creator A5004497930 @default.
• W3126787427 creator A5034903168 @default.
• W3126787427 creator A5058391948 @default.
• W3126787427 creator A5059942403 @default.
• W3126787427 creator A5065903112 @default.
• W3126787427 date "2021-02-01" @default.
• W3126787427 modified "2023-09-27" @default.
• W3126787427 title "Evaluation of microRNAs as potential biomarkers in circulating HPV-DNA-positive non-small cell lung cancer patients" @default.
• W3126787427 cites W1076271826 @default.
• W3126787427 cites W1569185746 @default.
• W3126787427 cites W1971310883 @default.
• W3126787427 cites W1980960740 @default.
• W3126787427 cites W1997133357 @default.
• W3126787427 cites W2001508508 @default.
• W3126787427 cites W2007240877 @default.
• W3126787427 cites W2010642040 @default.
• W3126787427 cites W2016534280 @default.
• W3126787427 cites W2035336344 @default.
• W3126787427 cites W2036178413 @default.
• W3126787427 cites W2051731996 @default.
• W3126787427 cites W2053855502 @default.
• W3126787427 cites W2057710111 @default.
• W3126787427 cites W2059633534 @default.
• W3126787427 cites W2081736014 @default.
• W3126787427 cites W2089467855 @default.
• W3126787427 cites W2093054447 @default.
• W3126787427 cites W2117712470 @default.
• W3126787427 cites W2153888645 @default.
• W3126787427 cites W2170449834 @default.
• W3126787427 cites W2222708997 @default.
• W3126787427 cites W2306942974 @default.
• W3126787427 cites W2336990224 @default.
• W3126787427 cites W2472014432 @default.
• W3126787427 cites W2477889876 @default.
• W3126787427 cites W2592748155 @default.
• W3126787427 cites W2607357461 @default.
• W3126787427 cites W2751872230 @default.
• W3126787427 cites W2760626914 @default.
• W3126787427 cites W2762033857 @default.
• W3126787427 cites W2770466820 @default.
• W3126787427 cites W2789605097 @default.
• W3126787427 cites W2800414687 @default.
• W3126787427 cites W2803223602 @default.
• W3126787427 cites W2893634359 @default.
• W3126787427 cites W2902120574 @default.
• W3126787427 cites W2906203576 @default.
• W3126787427 cites W2909909462 @default.
• W3126787427 cites W2951293788 @default.
• W3126787427 cites W2953740029 @default.
• W3126787427 cites W2965603616 @default.
• W3126787427 cites W2984985719 @default.
• W3126787427 cites W2999291727 @default.
• W3126787427 cites W320106238 @default.
• W3126787427 cites W4210738594 @default.
• W3126787427 doi "https://doi.org/10.1080/15384047.2021.1872155" @default.
• W3126787427 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7928039" @default.
• W3126787427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33535877" @default.
• W3126787427 hasPublicationYear "2021" @default.
• W3126787427 type Work @default.
• W3126787427 sameAs 3126787427 @default.
• W3126787427 citedByCount "4" @default.
• W3126787427 countsByYear W31267874272021 @default.
• W3126787427 countsByYear W31267874272022 @default.
• W3126787427 countsByYear W31267874272023 @default.
• W3126787427 crossrefType "journal-article" @default.
• W3126787427 hasAuthorship W3126787427A5000868340 @default.
• W3126787427 hasAuthorship W3126787427A5003518372 @default.
• W3126787427 hasAuthorship W3126787427A5004497930 @default.
• W3126787427 hasAuthorship W3126787427A5034903168 @default.
• W3126787427 hasAuthorship W3126787427A5058391948 @default.
• W3126787427 hasAuthorship W3126787427A5059942403 @default.
• W3126787427 hasAuthorship W3126787427A5065903112 @default.
• W3126787427 hasBestOaLocation W31267874271 @default.
• W3126787427 hasConcept C104317684 @default.
• W3126787427 hasConcept C121608353 @default.
• W3126787427 hasConcept C126322002 @default.
• W3126787427 hasConcept C143998085 @default.
• W3126787427 hasConcept C145059251 @default.
• W3126787427 hasConcept C2776256026 @default.
• W3126787427 hasConcept C48023723 @default.
• W3126787427 hasConcept C502942594 @default.
• W3126787427 hasConcept C54355233 @default.
• W3126787427 hasConcept C71924100 @default.
• W3126787427 hasConcept C86803240 @default.
• W3126787427 hasConceptScore W3126787427C104317684 @default.
• W3126787427 hasConceptScore W3126787427C121608353 @default.
• W3126787427 hasConceptScore W3126787427C126322002 @default.
• W3126787427 hasConceptScore W3126787427C143998085 @default.
• W3126787427 hasConceptScore W3126787427C145059251 @default.
• W3126787427 hasConceptScore W3126787427C2776256026 @default.
• W3126787427 hasConceptScore W3126787427C48023723 @default.
• W3126787427 hasConceptScore W3126787427C502942594 @default.
• W3126787427 hasConceptScore W3126787427C54355233 @default.
• W3126787427 hasConceptScore W3126787427C71924100 @default.

• next