FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3126799102> ?p ?o ?g. }

• W3126799102 abstract "Scope The consumption of red and processed meat, and not white meat, associates with the development of various Western diseases such as colorectal cancer and type 2 diabetes. This work aims at unraveling novel meat‐associated mechanisms that are involved in disease development. Methods and Results A non‐hypothesis driven strategy of untargeted metabolomics is applied to assess colon tissue from rats (fed a high dose of beef vs. white meat) and from pigs (fed red/processed meat vs. white meat), receiving a realistic human background diet. An increased carnitine metabolism is observed, which is reflected by higher levels of acylcarnitines and 3‐dehydroxycarnitine (rats and pigs) and trimethylamine‐ N ‐oxide (rats). While 3‐dehydroxycarnitine is higher in HT29 cells, incubated with colonic beef digests, acylcarnitine levels are reduced. This suggests an altered response from colon cancer cell line towards meat‐induced oxidative stress. Moreover, metabolic differences between rat and pigs are observed in N ‐glycolylneuraminic acid incorporation, prostaglandin, and fatty acid synthesis. Conclusion This study demonstrates elevated (acyl)carnitine metabolism in colon tissue of animals that follow a red meat‐based diet, providing mechanistic insights that may aid in explaining the nutritional‐physiological correlation between red/processed meat and Western diseases." @default.
• W3126799102 created "2021-02-15" @default.
• W3126799102 creator A5013848189 @default.
• W3126799102 creator A5029230958 @default.
• W3126799102 creator A5031907769 @default.
• W3126799102 creator A5044418194 @default.
• W3126799102 creator A5047656220 @default.
• W3126799102 creator A5054408108 @default.
• W3126799102 creator A5074888051 @default.
• W3126799102 creator A5077574177 @default.
• W3126799102 date "2021-03-01" @default.
• W3126799102 modified "2023-09-23" @default.
• W3126799102 title "Untargeted Metabolomics Reveals Elevated L‐Carnitine Metabolism in Pig and Rat Colon Tissue Following Red Versus White Meat Intake" @default.
• W3126799102 cites W1517711897 @default.
• W3126799102 cites W1531879407 @default.
• W3126799102 cites W157502360 @default.
• W3126799102 cites W1611854178 @default.
• W3126799102 cites W1811102606 @default.
• W3126799102 cites W1941284977 @default.
• W3126799102 cites W1968135196 @default.
• W3126799102 cites W1984112187 @default.
• W3126799102 cites W1996962547 @default.
• W3126799102 cites W2044175597 @default.
• W3126799102 cites W2044638285 @default.
• W3126799102 cites W2072090020 @default.
• W3126799102 cites W2078042320 @default.
• W3126799102 cites W2078599166 @default.
• W3126799102 cites W2092436074 @default.
• W3126799102 cites W2096073982 @default.
• W3126799102 cites W2101537600 @default.
• W3126799102 cites W2127151371 @default.
• W3126799102 cites W2130085747 @default.
• W3126799102 cites W2136482421 @default.
• W3126799102 cites W2149220733 @default.
• W3126799102 cites W2337352325 @default.
• W3126799102 cites W2468025180 @default.
• W3126799102 cites W2468206872 @default.
• W3126799102 cites W2513212958 @default.
• W3126799102 cites W2568083903 @default.
• W3126799102 cites W2580570975 @default.
• W3126799102 cites W2588513928 @default.
• W3126799102 cites W2601390445 @default.
• W3126799102 cites W2626783532 @default.
• W3126799102 cites W2765260670 @default.
• W3126799102 cites W2801490216 @default.
• W3126799102 cites W2810312055 @default.
• W3126799102 cites W2921005414 @default.
• W3126799102 cites W2940801579 @default.
• W3126799102 cites W2946414163 @default.
• W3126799102 cites W2971987844 @default.
• W3126799102 cites W2981643974 @default.
• W3126799102 doi "https://doi.org/10.1002/mnfr.202000463" @default.
• W3126799102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33550692" @default.
• W3126799102 hasPublicationYear "2021" @default.
• W3126799102 type Work @default.
• W3126799102 sameAs 3126799102 @default.
• W3126799102 citedByCount "3" @default.
• W3126799102 countsByYear W31267991022021 @default.
• W3126799102 countsByYear W31267991022023 @default.
• W3126799102 crossrefType "journal-article" @default.
• W3126799102 hasAuthorship W3126799102A5013848189 @default.
• W3126799102 hasAuthorship W3126799102A5029230958 @default.
• W3126799102 hasAuthorship W3126799102A5031907769 @default.
• W3126799102 hasAuthorship W3126799102A5044418194 @default.
• W3126799102 hasAuthorship W3126799102A5047656220 @default.
• W3126799102 hasAuthorship W3126799102A5054408108 @default.
• W3126799102 hasAuthorship W3126799102A5074888051 @default.
• W3126799102 hasAuthorship W3126799102A5077574177 @default.
• W3126799102 hasBestOaLocation W31267991022 @default.
• W3126799102 hasConcept C121608353 @default.
• W3126799102 hasConcept C134018914 @default.
• W3126799102 hasConcept C186151877 @default.
• W3126799102 hasConcept C21565614 @default.
• W3126799102 hasConcept C2776151105 @default.
• W3126799102 hasConcept C2778089274 @default.
• W3126799102 hasConcept C2778435403 @default.
• W3126799102 hasConcept C31903555 @default.
• W3126799102 hasConcept C526805850 @default.
• W3126799102 hasConcept C54355233 @default.
• W3126799102 hasConcept C60644358 @default.
• W3126799102 hasConcept C62231903 @default.
• W3126799102 hasConcept C86803240 @default.
• W3126799102 hasConceptScore W3126799102C121608353 @default.
• W3126799102 hasConceptScore W3126799102C134018914 @default.
• W3126799102 hasConceptScore W3126799102C186151877 @default.
• W3126799102 hasConceptScore W3126799102C21565614 @default.
• W3126799102 hasConceptScore W3126799102C2776151105 @default.
• W3126799102 hasConceptScore W3126799102C2778089274 @default.
• W3126799102 hasConceptScore W3126799102C2778435403 @default.
• W3126799102 hasConceptScore W3126799102C31903555 @default.
• W3126799102 hasConceptScore W3126799102C526805850 @default.
• W3126799102 hasConceptScore W3126799102C54355233 @default.
• W3126799102 hasConceptScore W3126799102C60644358 @default.
• W3126799102 hasConceptScore W3126799102C62231903 @default.
• W3126799102 hasConceptScore W3126799102C86803240 @default.
• W3126799102 hasFunder F4320321730 @default.
• W3126799102 hasIssue "7" @default.
• W3126799102 hasLocation W31267991021 @default.
• W3126799102 hasLocation W31267991022 @default.
• W3126799102 hasLocation W31267991023 @default.

• next