Matches in SemOpenAlex for { <https://semopenalex.org/work/W3127021000> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W3127021000 abstract "BACKGROUND AND PURPOSE To investigate the change in serum dehydroepiandrosterone sulfate (DHEAS) and androstenedione concentrations during childhood and to clarify the relationship between adrenarche and gonadarche. METHODS A cross-sectional study of 577 healthy children (297 boys and 280 girls), with ages ranging from 5 days to 12 years was conducted. After complete physical examination and recording of any sign of puberty, blood samples were drawn for the determination of serum DHEAS and androstenedione concentrations. For comparison, blood samples were also drawn from 39 normal adults, 23 men and 16 women. RESULTS In both genders, the DHEAS and androstenedione levels at birth were 3.0 +/- 1.3 mumol/L and 4.1 +/- 2.3 nmol/L, respectively. They fell rapidly within 6 months, and were maintained at a low level until 6 years of age. After the age of 6, the levels of both adrenal androgens were significantly increased (p < 0.05). Adrenarche occurred at the age of 7.7 +/- 1.1 years in boys and at the age of 7.7 +/- 1.0 years in girls. Gonadarche occurred at the age of 11.2 +/- 0.8 years in boys (n = 33) and at the age of 10.3 +/- 0.8 years in girls (n = 46). The onset of adrenarche occurred about 2 to 3 years earlier than the onset of puberty (p < 0.001). CONCLUSIONS Serum levels of adrenal androgens change dramatically during childhood. Serum concentration of DHEAS is a good marker for adrenal androgens production because gonadal androgens may interfere with serum concentration of androstenedione. For Taiwanese children, the onset of adrenarche occurred between the ages of 6 and 8 years, which was 2 to 3 years earlier than the onset of puberty." @default.
- W3127021000 created "2021-02-15" @default.
- W3127021000 creator A5013273626 @default.
- W3127021000 creator A5013622964 @default.
- W3127021000 creator A5080973459 @default.
- W3127021000 creator A5084845300 @default.
- W3127021000 date "2004-01-01" @default.
- W3127021000 modified "2023-09-25" @default.
- W3127021000 title "Physiological changes of adrenal androgens in childhood." @default.
- W3127021000 hasPublicationYear "2004" @default.
- W3127021000 type Work @default.
- W3127021000 sameAs 3127021000 @default.
- W3127021000 citedByCount "0" @default.
- W3127021000 crossrefType "journal-article" @default.
- W3127021000 hasAuthorship W3127021000A5013273626 @default.
- W3127021000 hasAuthorship W3127021000A5013622964 @default.
- W3127021000 hasAuthorship W3127021000A5080973459 @default.
- W3127021000 hasAuthorship W3127021000A5084845300 @default.
- W3127021000 hasConcept C121207290 @default.
- W3127021000 hasConcept C126322002 @default.
- W3127021000 hasConcept C134018914 @default.
- W3127021000 hasConcept C2776683971 @default.
- W3127021000 hasConcept C2776992908 @default.
- W3127021000 hasConcept C2777911890 @default.
- W3127021000 hasConcept C2778367240 @default.
- W3127021000 hasConcept C2779279991 @default.
- W3127021000 hasConcept C2780657110 @default.
- W3127021000 hasConcept C2910820727 @default.
- W3127021000 hasConcept C71315377 @default.
- W3127021000 hasConcept C71924100 @default.
- W3127021000 hasConceptScore W3127021000C121207290 @default.
- W3127021000 hasConceptScore W3127021000C126322002 @default.
- W3127021000 hasConceptScore W3127021000C134018914 @default.
- W3127021000 hasConceptScore W3127021000C2776683971 @default.
- W3127021000 hasConceptScore W3127021000C2776992908 @default.
- W3127021000 hasConceptScore W3127021000C2777911890 @default.
- W3127021000 hasConceptScore W3127021000C2778367240 @default.
- W3127021000 hasConceptScore W3127021000C2779279991 @default.
- W3127021000 hasConceptScore W3127021000C2780657110 @default.
- W3127021000 hasConceptScore W3127021000C2910820727 @default.
- W3127021000 hasConceptScore W3127021000C71315377 @default.
- W3127021000 hasConceptScore W3127021000C71924100 @default.
- W3127021000 hasLocation W31270210001 @default.
- W3127021000 hasOpenAccess W3127021000 @default.
- W3127021000 hasPrimaryLocation W31270210001 @default.
- W3127021000 hasRelatedWork W1810483250 @default.
- W3127021000 hasRelatedWork W2014097788 @default.
- W3127021000 hasRelatedWork W2030271794 @default.
- W3127021000 hasRelatedWork W2030617780 @default.
- W3127021000 hasRelatedWork W2031981194 @default.
- W3127021000 hasRelatedWork W2047298981 @default.
- W3127021000 hasRelatedWork W2055333124 @default.
- W3127021000 hasRelatedWork W2079673406 @default.
- W3127021000 hasRelatedWork W2115004603 @default.
- W3127021000 hasRelatedWork W2130731479 @default.
- W3127021000 hasRelatedWork W2171444920 @default.
- W3127021000 hasRelatedWork W2178183120 @default.
- W3127021000 hasRelatedWork W2352769814 @default.
- W3127021000 hasRelatedWork W2406675518 @default.
- W3127021000 hasRelatedWork W2414891872 @default.
- W3127021000 hasRelatedWork W2611912442 @default.
- W3127021000 hasRelatedWork W2810063969 @default.
- W3127021000 hasRelatedWork W2919688695 @default.
- W3127021000 hasRelatedWork W3014972337 @default.
- W3127021000 hasRelatedWork W57983311 @default.
- W3127021000 isParatext "false" @default.
- W3127021000 isRetracted "false" @default.
- W3127021000 magId "3127021000" @default.
- W3127021000 workType "article" @default.