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• W3127239132 endingPage "122153" @default.
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• W3127239132 abstract "Since the interest in the biomedical applications of inorganic nanoparticles (NPs) has rapidly grown over the last decades, there is a need for a thorough characterization of bio-nano interactions. NPs introduced to the body (mostly intravenously) encounter plasma proteins, that instantly create a so-called “protein corona” on the NPs surface, giving the nanomaterial a new biological identity. Type of the proteins that interact with NPs may affect the in vivo fate of NPs. For that reason, it is particularly important to establish analytical methods capable of corona protein identification. Bottom-up proteomics is most often used for that purpose. A crucial part of the experiment is sample preparation, as it is already proven that different protocols may lead to distinct results. This review is aimed at providing a characterization of two main stages of sample preparation: separation of NPs with protein corona from the unbound proteins and the digestion of corona proteins. Separation techniques such as centrifugation, magnetic separation, and chromatography and three digestion methods (in-gel, in-solution, and on-particle) are described with special emphasis paid on their advantages and disadvantages as well as their influence on the result of identification. This paper also indicates the need for standardization of protein corona identification protocols, as some of the proteins may be preferentially detected while applying a particular digestion procedure." @default.
• W3127239132 created "2021-02-15" @default.
• W3127239132 creator A5012582994 @default.
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• W3127239132 date "2021-05-01" @default.
• W3127239132 modified "2023-10-17" @default.
• W3127239132 title "How to effectively prepare a sample for bottom-up proteomic analysis of nanoparticle protein corona? A critical review" @default.
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• W3127239132 cites W1975523244 @default.
• W3127239132 cites W1976724213 @default.
• W3127239132 cites W1981701278 @default.
• W3127239132 cites W1989090339 @default.
• W3127239132 cites W1990796256 @default.
• W3127239132 cites W2006806281 @default.
• W3127239132 cites W2006984831 @default.
• W3127239132 cites W2007018764 @default.
• W3127239132 cites W2016395055 @default.
• W3127239132 cites W2021876818 @default.
• W3127239132 cites W2034121060 @default.
• W3127239132 cites W2040806919 @default.
• W3127239132 cites W2052823596 @default.
• W3127239132 cites W2064811596 @default.
• W3127239132 cites W2065794292 @default.
• W3127239132 cites W2073371147 @default.
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• W3127239132 cites W2087543777 @default.
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• W3127239132 doi "https://doi.org/10.1016/j.talanta.2021.122153" @default.
• W3127239132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33676702" @default.
• W3127239132 hasPublicationYear "2021" @default.
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